ORF Clones Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
Voluntary Physical Activity Abolishes the Proliferative Tumor Growth Microenvironment Created by Adipose Tissue in Animals Fed a High Fat Diet J. Appl. Physiol. May 2016 ORF Clones Custom plasmid
AKT3 An Akt3 splice variant lacking the serine 472 phosphorylation site promotes apoptosis and suppresses mammary tumorigenesis Cancer Res. 2017 ORF Clones RC221051
AR Mutational analysis of the androgen receptor (NR3C4) gene in patients with 46,XY DSD Gene 2017 ORF Clones RG215316
ARF6 β-Cryptoxanthin reduced lung tumor multiplicity and inhibited lung cancer cell motility by down-regulating nicotinic acetylcholine receptor α7 signaling Cancer Prev Res (Phila) 2016 ORF Clones RC203600
ARIH1 E6AP/UBE3A catalyzes encephalomyocarditis virus 3C protease polyubiquitylation and promotes its concentration reduction in virus-infected cells Biochem. Biophys. Res. Commun. 2017 ORF Clones MR207099
ARIH2 E6AP/UBE3A catalyzes encephalomyocarditis virus 3C protease polyubiquitylation and promotes its concentration reduction in virus-infected cells Biochem. Biophys. Res. Commun. 2017 ORF Clones MR207887
BECN1 CaMKII-mediated Beclin 1 phosphorylation regulates autophagy that promotes degradation of Id and neuroblastoma cell differentiation Nat Commun 2017 ORF Clones RC201629
CD86 Single-molecule diffusion-based estimation of GPCR activity bioRxiv 2017 ORF Clones RG217341
CDH1 MiR-23a promotes TGF-β1-induced EMT and tumor metastasis in breast cancer cells by directly targeting CDH1 and activating Wnt/β-catenin signaling Oncotarget 2017 ORF Clones RC220731
CKAP4 Overexpression of CKAP4 is Associated with Poor Prognosis in Clear Cell Renal Cell Carcinoma and Functions via Cyclin B Signaling Journal of Cancer 2017 ORF Clones RC210270
CTCFL Investigation of fusion gene expression in HCT116 cells Oncology Letters 2017 ORF Clones RC216042
DACT1 MiR-324-3p promotes tumor growth through targeting DACT1 and activation of Wnt/β-catenin pathway in hepatocellular carcinoma Oncotarget 2017 ORF Clones RC215557
EEF1A1 Proteomic analyses of signalling complexes associated with receptor tyrosine kinase identify novel members of fibroblast growth factor receptor 3 interactome Cell. Signal. 2017 ORF Clones RC209697
EGR1 Estrogen-induced transcription factor EGR1 regulates c-Kit transcription in the mouse uterus to maintain uterine receptivity for embryo implantation Mol. Cell. Endocrinol. 2017 ORF Clones RC209956
EPHA7 Ligand-dependent EphA7 signaling inhibits prostate tumor growth and progression Cell Death Dis 2017 ORF Clones RC226293
FIG4 Ebola virus requires phosphatidylinositol (3,5) bisphosphate production for efficient viral entry Virology 2017 ORF Clones RC207192
FKBP5 A regulatory role for the co-chaperone FKBP51s in PD-L1 expression in glioma Oncotarget 2017 ORF Clones RC210608
FUS HDAC6 inhibition reverses axonal transport defects in motor neurons derived from FUS-ALS patients Nat Commun 2017 ORF Clones RC201808
GATA3 NKL homeobox gene MSX1 acts like a tumor suppressor in NK-cell leukemia Oncotarget 2017 ORF Clones RC211904
GLI1 Data on peptides identified by mass spectrometry analysis of in vitro DYRK1A-mediated phosphorylation sites on GLI1 Data Brief 2017 ORF Clones RC201110
HHEX NKL homeobox gene MSX1 acts like a tumor suppressor in NK-cell leukemia Oncotarget 2017 ORF Clones RC204815
HSF1 Deregulated c-Myc requires a functional HSF1 for experimental and human hepatocarcinogenesis metabolism 2017 ORF Clones RC200314
IRF4 NKL homeobox gene MSX1 acts like a tumor suppressor in NK-cell leukemia Oncotarget 2017 ORF Clones RC204876
KLF14 Germline deletion of Krüppel-like factor 14 does not increase risk of diet induced metabolic syndrome in male C57BL/6 mice Biochim. Biophys. Acta 2017 ORF Clones MR221172
KLF4 MicroRNA-18a promotes proliferation and metastasis in hepatocellular carcinoma via targeting KLF4 Oncotarget 2017 ORF Clones RC206691
MAFF System modeling reveals the molecular mechanisms of HSC cell cycle alteration mediated by Maff and Egr3 under leukemia BMC Syst Biol 2017 ORF Clones MR201170
MSX1 NKL homeobox gene MSX1 acts like a tumor suppressor in NK-cell leukemia Oncotarget 2017 ORF Clones RC205682
MYC Downregulation of miR-16 via URGCP pathway contributes to glioma growth Sci Rep 2017 ORF Clones RC201611
NAPRT Novel NAPRT specific antibody identifies small cell lung cancer and neuronal cancers as promising clinical indications for a NAMPT inhibitor/niacin co-administration strategy Oncotarget 2017 ORF Clones RC204356
NKA Low dose ouabain stimulates NaK ATPase α1 subunit association with angiotensin II type 1 receptor in renal proximal tubule cells Biochim. Biophys. Acta 2016 ORF Clones RG214943
P4HB Endoplasmic reticulum chaperone prolyl 4-hydroxylase, beta polypeptide (P4HB) promotes malignant phenotypes in glioma via MAPK signaling Oncotarget 2017 ORF Clones RC202275
PATL2 Biallelic Mutations in PATL2 Cause Female Infertility Characterized by Oocyte Maturation Arrest The American Journal of Human Genetics 2017 ORF Clones MR212417
PRMT1 PRMT1 and JMJD6 dependent arginine methylation regulate HNF4α expression and hepatocyte proliferation Hepatology 2017 ORF Clones RC224239
PTGS2 Arsenic Induces p62 Expression to Form a Positive Feedback Loop with Nrf2 in Human Epidermal Keratinocytes: Implications for Preventing Arsenic-Induced Skin Cancer Molecules 2017 ORF Clones MG227684
RAB27A Rab27A overexpression promotes bladder cancer proliferation and chemoresistance through regulation of NF-κB signaling. Oncotarget 2017 ORF Clones RC217900
RAB27B Downregulation of serum RAB27B confers improved prognosis and is associated with hepatocellular carcinoma progression through PI3K-AKT-P21 signaling Oncotarget 2017 ORF Clones RC206519
RALY The hnRNP RALY regulates transcription and cell proliferation by modulating the expression of specific factors, including the proliferation-marker E2F1 J. Biol. Chem. 2017 ORF Clones RC210723
RELA Downregulation of miR-16 via URGCP pathway contributes to glioma growth Sci Rep 2017 ORF Clones RC220780
SCD1 An N-terminal di-proline motif is essential for fatty acid-dependent degradation of Δ9-desaturase in Drosophila J. Biol. Chem. 2017 ORF Clones MR225893
SHOX2 Proteomic analyses of signalling complexes associated with receptor tyrosine kinase identify novel members of fibroblast growth factor receptor 3 interactome Cell. Signal. 2017 ORF Clones RG219520
SLC29A1 Contribution of Equilibrative Nucleoside Transporter(s) to Intestinal Basolateral and Apical Transports of Anticancer Trifluridine Biopharm Drug Dispos 2017 ORF Clones RC201177
SPAG9 Effect of SPAG9 on migration, invasion and prognosis of prostate cancer Int J Clin Exp Patho 2017 ORF Clones RC226382
SPHK1 Sphingosine-1-phosphate suppresses chondrosarcoma metastasis by upregulation of tissue inhibitor of metalloproteinase 3 through suppressing miR-101 expression Mol Oncol 2017 ORF Clones RC203398
STAM Proteomic analyses of signalling complexes associated with receptor tyrosine kinase identify novel members of fibroblast growth factor receptor 3 interactome Cell. Signal. 2017 ORF Clones RC219230
STK33 STK33 promotes growth and progression of pancreatic cancer as a critical downstream mediator of HIF-1α Cancer Res. 2017 ORF Clones RC206910
STMN1 Overexpression of stathmin plays a pivotal role in the metastasis of esophageal squamous cell carcinoma Oncotarget 2017 ORF Clones RC205073
TMEM17 TMEM17 depresses invasion and metastasis in lung cancer cells via ERK signaling pathway Oncotarget 2017 ORF Clones RC208232
TRIM22 TRIM22 confers poor prognosis and promotes epithelial-mesenchymal transition through regulation of AKT/GSK3β/β-catenin signaling in non-small cell lung cancer Oncotarget 2017 ORF Clones RC207431
TSHR Periostin silencing suppresses the aggressive phenotype of thyroid carcinoma cells by suppressing the Akt/thyroid stimulating hormone receptor axis Cytotechnology 2017 ORF Clones RC220499
VPS37A HCRP1 downregulation confers poor prognosis and induces chemoresistance through regulation of EGFR-AKT pathway in human gastric cancer Virchows Arch. 2017 ORF Clones RC209716
WT1 The CUG-translated WT1, not AUG-WT1, is an oncogene Carcinogenesis 2017 ORF Clones RC220079
ZEB1 TLE1 inhibits anoikis and promotes tumorigenicity in human lung cancer cells through ZEB1-mediated E-cadherin repression Oncotarget 2017 ORF Clones RC217704
ZFPM2 Identification of ZFPM2 mutations in sporadic conotruncal heart defect patients Mol. Genet. Genomics 2017 ORF Clones RC214338
A2ML1 Integrating Functional Analysis in the Next-Generation Sequencing Diagnostic Pipeline of RASopathies Sci Rep 2018 ORF Clones RC219615
AAAS Loss of the nucleoporin Aladin in central nervous system and fibroblasts of Allgrove Syndrome Hum. Mol. Genet. 2019 ORF Clones RC200154
AADAT Improvement in detrusor-sphincter dyssynergia by bladder-wall injection of replication-defective herpes simplex virus vector-mediated gene delivery of kynurenine aminotransferase II in spinal cord injury rats Spinal Cord 2016 ORF Clones RG223277
Aadat Astrocytic and neuronal localization of kynurenine aminotransferase-2 in the adult mouse brain Brain Struct Funct 2016 ORF Clones MC200934
AADAT Effect of urethral wall injection of replication-defective herpes simplex virus-mediated gene transfer of kynurenine aminotransferase on urethral pressure in spinal cord-injured rats Neurourol. Urodyn. 2016 ORF Clones RG223277
AADAT Herpes simplex virus vector-mediated gene transfer of kynurenine aminotransferase improves detrusor overactivity in spinal cord-injured rats Gene Ther. Mar 2014 ORF Clones RG223277
AANAT Melatonin exerts by an autocrine loop antiproliferative effects in cholangiocarcinoma; its synthesis is reduced favoring cholangiocarcinoma growth Am J Physiol Gastrointest Liver Physiol, Oct 2011; 301: G623 - G633. ORF Clones RC210142
AATF Che1/AATF interacts with subunits of the histone acetyltransferase core module of SAGA complexes PLoS ONE 2017 ORF Clones RC200070
AATF Mitochondrial uncoupling protein (UCP2) gene expression is regulated by miR-2909 Blood Cells Mol. Dis. Jun 2015 ORF Clones RC200070
ABCA1 Protease-activated receptor 1 inhibits cholesterol efflux and promotes atherogenesis via cullin 3-mediated degradation of the ABCA1 transporter J. Biol. Chem. 2018 ORF Clones RC221861
ABCA4 The CFTR Corrector, VX-809 (Lumacaftor), Rescues ABCA4 Trafficking Mutants: a Potential Treatment for Stargardt Disease Cell. Physiol. Biochem. 2019 ORF Clones RG213827
ABCA4 Rescuing trafficking mutants of the ATP binding cassette protein, ABCA4, with small molecule correctors as a treatment for Stargardt eye disease J. Biol. Chem. Jun 2015 ORF Clones RG213827
ABCA5 ABCA5 Regulates Amyloid-ß Peptide Production and is Associated with Alzheimer's Disease Neuropathology J. Alzheimers Dis. Aug 2014 ORF Clones RC213865
ABCB1 Leveraging Mathematical Modeling to Quantify Pharmacokinetic and Pharmacodynamic Pathways: Equivalent Dose Metric Front. Physiol. 2019 ORF Clones RG216080
ABCB1 Doxorubicin-conjugated dexamethasone induced MCF-7 apoptosis without entering the nucleus and able to overcome MDR-1-induced resistance Drug Des Devel Ther 2018 ORF Clones RG216080
ABCB1 Variable Cell Line Pharmacokinetics Contribute to Non-Linear Treatment Response in Heterogeneous Cell Populations Ann Biomed Eng 2018 ORF Clones RG216080
ABCB1 Saikosaponins A, C and D enhance liver-targeting effects of anticancer drugs by modulating drug transporters Oncotarget 2017 ORF Clones RG216080
ABCB1 Clerosterol from vinegar-baked radix bupleuri modifies drug transport Oncotarget 2017 ORF Clones RG216080
ABCB1 Multiplicity of acquired cross-resistance in paclitaxel-resistant cancer cells is associated with feedback control of TUBB3 via FOXO3a-mediated ABCB1 regulation Oncotarget Apr 2016 ORF Clones RG216080
ABCB1 Temozolomide reverses doxorubicin resistance by inhibiting P-glycoprotein in malignant glioma cells J. Neurooncol. Nov 2015 ORF Clones RC216080
ABCB1 Multidrug resistance protein 1 reduces the aggregation of mutant huntingtin in neuronal cells derived from the Huntington's disease R6/2 model Sci Rep Nov 2015 ORF Clones RG216080
ABCB1 Temozolomide competes for P-glycoprotein and contributes to chemoresistance in glioblastoma cells Cancer Lett. Jul 2015 ORF Clones RG216080
ABCB1 Microchamber Device for Detection of Transporter Activity of Adherent Cells Frontiers in Bioengineering and Biotechnology Mar 2015 ORF Clones RG216080
ABCB1 A microwell device for measurement of membrane transport of adherent cells MEMS Jan 2015 ORF Clones RG216080
ABCB1 MDR1 Transporter Protects Against Paraquat-Induced Toxicity in Human and Mouse Proximal Tubule Cells Toxicol. Sci. July 2014 ORF Clones RC216080
ABCB10 Dimeric ferrochelatase bridges ABCB7 and ABCB10 homodimers in an architecturally defined molecular complex required for heme biosynthesis Haematologica 2019 ORF Clones RC209046
ABCB1A P-glycoprotein attenuates DNA repair activity in multidrug-resistant cells by acting through the Cbp-Csk-Src cascade Oncotarget 2017 ORF Clones MR227524
ABCB8 Identification of an ATP-sensitive potassium channel in mitochondria Nature 2019 ORF Clones RC224948
ABCB8 miR-504 regulates chemosensitivity in triple negative breast cancer (TNBC) cells via targeting ABCB8 Int J Clin Exp Pathol 2017 ORF Clones RC224948
ABCC1 Ursolic acid enhances the therapeutic effects of oxaliplatin in colorectal cancer by inhibition of drug resistance Cancer Sci.2017 ORF Clones RC218182
ABCC2 Structure affinity relationship and docking studies of flavonoids as substrates of multidrug-resistant associated protein 2 (MRP2) in MDCK/MRP2 cells Food Chemistry 2019 ORF Clones RC218976
ABCC4 An unexpected protein interaction promotes drug resistance in leukemia Nat Commun 2017 ORF Clones RG223032
ABCC8 A New Familial Form of a Late-onset, Persistent Hyperinsulinemic Hypoglycemia of Infancy caused by a Novel Mutation in KCNJ11 Channels (Austin)2017 ORF Clones RC215352
ABCG1 RAGE Suppresses ABCG1-Mediated Macrophage Cholesterol Efflux in Diabetes Diabetes Aug 2015 ORF Clones RG206478
ABCG2 Correlation Between Membrane Protein Concentrations and Transcellular Transport Activity for Breast Cancer Resistance Protein Drug Metabolism and Disposition 2017 ORF Clones MR209819
ABCG2 Correlation between Membrane Protein Expression Levels and Transcellular Transport Activity for Breast Cancer Resistance Protein Drug Metab. Dispos. 2017 ORF Clones MR209819
ABCG2 Correlation between Membrane Protein Expression Levels and Transcellular Transport Activity for Breast Cancer Resistance Protein Drug Metab. Dispos. 2017 ORF Clones RG205640
ABCG2 Loss of microRNA-27b contributes to breast cancer stem cell generation by activating ENPP1 Nat Commun Jun 2015 ORF Clones RC205640
ABHD6 Biochemical and Proteomic Characterization of Recombinant Human α/β Hydrolase Domain 6 Sci Rep 2019 ORF Clones RC200915
ABHD6 a/ß-Hydrolase Domain-6-Accessible Monoacylglycerol Controls Glucose-Stimulated Insulin Secretion Cell Metab. May 2014 ORF Clones RG200915
ABL1 Identification of fusion genes and characterization of transcriptome features in T-cell acute lymphoblastic leukemia Proc. Natl. Acad. Sci. U.S.A. 2017 ORF Clones RC220600
ABL2 ABL2 suppresses FLT3-ITD-induced cell proliferation through negative regulation of AKT signaling Oncotarget 2017 ORF Clones RC222989
ACAA2 H2A.Z-dependent and-independent recruitment of metabolic enzymes to chromatin required for histone modifications bioRxiv 2019 ORF Clones MG206222
ACACA Acetyl-CoA carboxylase a promotion of glucose-mediated fatty acid synthesis enhances survival of hepatocellular carcinoma in mice and patients Hepatology Dec 2015 ORF Clones RC218293
ACBD3 Enterovirus 3A facilitates viral replication by promoting PI4KB-ACBD3 interaction J. Virol. 2017 ORF Clones RC208434
ACBD3 The Golgi protein ACBD3 facilitates Enterovirus 71 replication by interacting with 3A Sci Rep 2017 ORF Clones RC208434
ACE2 Identification of residues controlling restriction versus enhancing activities of IFITM proteins on the entry of human coronaviruses J. Virol. 2017 ORF Clones RC208442
ACE2 microRNA-1246 mediates lipopolysaccharide-induced pulmonary endothelial cell apoptosis and acute lung injury by targeting angiotensin-converting enzyme 2 Am J Transl Res 2017 ORF Clones RC208442
ACE2 Inhibition of ER glucosidases impairs SARS-CoV and HCoV-NL63 spike protein-mediated entry by altering the glycan processing of ACE2 Antimicrob. Agents Chemother. Oct 2014 ORF Clones RC208442
ACKR3 CXCR7 expression in diffuse large B-cell lymphoma identifies a subgroup of CXCR4+ patients with good prognosis PLoS ONE 2018 ORF Clones RG206092
ACKR4 Loss of atypical chemokine receptor 4 facilitates C-C motif chemokine ligand 21-mediated tumor growth and invasion in nasopharyngeal carcinoma Exp Ther Med 2019 ORF Clones RC210172
ACKR4 Loss of atypical chemokine receptor 4 facilitates C‑C motif chemokine ligand 21‑mediated tumor growth and invasion in nasopharyngeal carcinoma Exp Ther Med 2018 ORF Clones RC210172
ACO1 An Investigation of the Effect of MN2+ on the FTH1 IRE-IRP Complex Thesis May 2015 ORF Clones RC201857
ACOT1 Acyl-CoA Thioesterase 1 (ACOT1) Regulates PPARα to Couple Fatty Acid Flux With Oxidative Capacity During Fasting Diabetes 2017 ORF Clones MR224801
ACOT1 Cardiomyocyte specific expression of Acyl-coA thioesterase 1 attenuates sepsis induced cardiac dysfunction and mortality Biochem. Biophys. Res. Commun. Oct 2015 ORF Clones RC221302
Acot11 Regulation of Fatty Acid Trafficking in Liver by Thioesterase Superfamily Member 1 J. Lipid Res. 2017 ORF Clones MG209248
ACOT7 Inflammatory Stimuli Induce Acyl-CoA Thioesterase 7 and Remodeling of Phospholipids Containing Unsaturated Long (≥C20)-Acyl Chains in Macrophages J. Lipid Res. 2017 ORF Clones MR216800
ACPT Testicular acid phosphatase induces odontoblast differentiation and mineralization Cell Tissue Res. Nov 2015 ORF Clones MR225986
ACSF2 Using CETSA assay and a mathematical model to reveal dual Bcl-2/Mcl-1 inhibition and on-target mechanism for ABT-199 and S1 Eur J Pharm Sci 2019 ORF Clones RC204368
ACSL4 Signature molecules expressed differentially in a liver disease stage-specific manner by HIV-1 and HCV co-infection PLoS ONE 2018 ORF Clones RC205356
Acta2 The role of a-smooth muscle actin in fibroblast-mediated matrix contraction and remodeling Biochim. Biophys. Acta 2016 ORF Clones MR205873
ACTB Actin Is Crucial for All Kinetically Distinguishable Forms of Endocytosis at Synapses Neuron 2016 ORF Clones RC203643
ACTB Actin Is Crucial for All Kinetically Distinguishable Forms of Endocytosis at Synapses Neuron 2016 ORF Clones RC201730
ACTB Chaperonin TRiC/CCT Modulates the Folding and Activity of Leukemogenic Fusion Oncoprotein AML1-ETO J. Biol. Chem. Dec 2015 ORF Clones RC203643
ACTB Experimental validation of predicted subcellular localizations of human proteins BMC Res Notes Dec 2014 ORF Clones RC100034
ACTG1 Spectrum of diverse genomic alterations define non-clear cell renal carcinoma subtypes Nat. Genet. Nov 2014 ORF Clones RC201730
ACTG2 ACTG2 variants impair actin polymerization in sporadic Megacystis Microcolon Intestinal Hypoperistalsis Syndrome Hum. Mol. Genet. Dec 2015 ORF Clones RC203151
ACTN2 a-Actinin-2 Mediates Spine Morphology and Assembly of the Post-Synaptic Density in Hippocampal Neurons PLoS ONE July 2014 ORF Clones RG208531
ACVRL1 The role of Alk-1 and Alk-5 in the mechanosensing of chondrocytes Cell. Mol. Biol. Lett. Dec 2014 ORF Clones RR205137
ACY1 Family-wide Annotation of Enzymatic Pathways by Parallel In Vivo Metabolomics Cell Chem Biol 2019 ORF Clones MR206415
ADAM10 An activated form of ADAM10 is tumor selective and regulates cancer stem-like cells and tumor growth J. Exp. Med. 2016 ORF Clones RC215457
ADAM11 Monoclonal Antibody DL11C8 Identifies ADAM23 as a Component of Lipid Raft Microdomains Neuroscience 2018 ORF Clones MR216099
ADAM22 Monoclonal Antibody DL11C8 Identifies ADAM23 as a Component of Lipid Raft Microdomains Neuroscience 2018 ORF Clones MR222778
ADAM22 ADAM22 and ADAM23 modulate the targeting of the Kv1 channel-associated protein LGI1 to the axon initial segment bioRxiv 2018 ORF Clones RC223610
ADAM22 Inhibitory axons are targeted in hippocampal cell culture by anti-Caspr2 autoantibodies associated with limbic encephalitis Front Cell Neurosci Jul 2015 ORF Clones RC223610
ADAM23 Monoclonal Antibody DL11C8 Identifies ADAM23 as a Component of Lipid Raft Microdomains Neuroscience 2018 ORF Clones MR223654
ADAM23 ADAM22 and ADAM23 modulate the targeting of the Kv1 channel-associated protein LGI1 to the axon initial segment bioRxiv 2018 ORF Clones RC222765
ADAM23 Inhibitory axons are targeted in hippocampal cell culture by anti-Caspr2 autoantibodies associated with limbic encephalitis Front Cell Neurosci Jul 2015 ORF Clones RC222765
ADAM33 Regulation of ectodomain shedding of ADAM33 in vitro and in vivo J. Allergy Clin. Immunol. 2019 ORF Clones MR217277
Adam33 Soluble ADAM33 initiates airway remodeling to promote susceptibility for allergic asthma in early life. JCI Insight 2016 ORF Clones MR217277
ADAM9 microRNA-590 suppresses the tumorigenesis and invasiveness of non-small cell lung cancer cells by targeting ADAM9 Mol. Cell. Biochem. 2016 ORF Clones RC222453
ADAMDEC1 Epidermal Growth Factor (EGF) Autocrine Activation of Human Platelets Promotes EGF Receptor-Dependent Oral Squamous Cell Carcinoma Invasion, Migration, and Epithelial Mesenchymal Transition J. Immunol. 2018 ORF Clones RC210181
ADAMDEC1 The soluble protease ADAMDEC1 released from activated platelets hydrolyzes platelet membrane pro-EGF to active high molecular weight EGF J. Biol. Chem. 2017 ORF Clones RC210181
ADAMTS1 Cleavage of Fibulin-2 by the aggrecanases ADAMTS-4 and ADAMTS-5 contributes to the tumorigenic potential of breast cancer cells Oncotarget 2017 ORF Clones RC205984
ADAMTS12 Neurocan is a New Substrate for the ADAMTS12 Metalloprotease: Potential Implications in Neuropathies Cell. Physiol. Biochem. 2019 ORF Clones MR224137
ADAMTS4 Astrocyte-selective AAV-ADAMTS4 gene therapy combined with hindlimb rehabilitation promotes functional recovery after spinal cord injury bioRxiv 2019 ORF Clones RC209226
ADAMTS4 Cleavage of Fibulin-2 by the aggrecanases ADAMTS-4 and ADAMTS-5 contributes to the tumorigenic potential of breast cancer cells Oncotarget 2017 ORF Clones RC209226
ADAMTS9 Mutations of ADAMTS9 Cause Nephronophthisis-Related Ciliopathy Am. J. Hum. Genet. 2019 ORF Clones RC217581
ADAMTS9 ADAMTS9 Regulates Skeletal Muscle Insulin Sensitivity Through Extracellular Matrix Alterations Diabetes 2019 ORF Clones RC217581
ADAR The Role of ADAR1 and ADAR2 in the Regulation of miRNA-21 in Idiopathic Pulmonary Fibrosis Lung 2018 ORF Clones RC207522
ADAR DEPDC5 and NPRL3 modulate cell size, filopodial outgrowth, and localization of mTOR in neural progenitor cells and neurons Neurobiol. Dis. 2018 ORF Clones MR21587
ADAR Adenosine-to-inosine RNA editing controls cathepsin S expression in atherosclerosis by enabling HuR-mediated post-transcriptional regulation Nat. Med. 2016 ORF Clones SC311326
ADARB1 The Role of ADAR1 and ADAR2 in the Regulation of miRNA-21 in Idiopathic Pulmonary Fibrosis Lung 2018 ORF Clones RC209073
ADAT2 Formation of tRNA Wobble Inosine in Humans Is Disrupted by a Millennia-Old Mutation Causing Intellectual Disability Mol. Cell. Biol. 2019 ORF Clones RC212395
ADAT2 Formation of tRNA wobble inosine in humans is perturbed by a millennia-old mutation linked to intellectual disability bioRxiv 2018 ORF Clones RC212395
ADCY1 Neomorphic effects of recurrent somatic mutations in Yin Yang 1 in insulin-producing adenomas Proc. Natl. Acad. Sci. U.S.A. Mar 2015 ORF Clones RC222738
ADCY10 Identification and Functional Analysis of Alternatively Spliced Isoforms of Soluble Adenylyl Cyclase in Human Bronchial Epithelial Cells Thesis Dec 2014 ORF Clones RC214876
ADCY6 Neomorphic effects of recurrent somatic mutations in Yin Yang 1 in insulin-producing adenomas Proc. Natl. Acad. Sci. U.S.A. Mar 2015 ORF Clones RC214902
ADCY7 Auto-regulation of Secretory Flux by Sensing and Responding to the Folded Cargo Protein Load in the Endoplasmic Reticulum Cell 2019 ORF Clones RC214351
Add3 Knockdown of Add3 Impairs the Myogenic Response of Renal Afferent Arterioles and Middle Cerebral Arteries Am. J. Physiol. Renal Physiol 2016 ORF Clones RR207822
ADGRL4 Identification of key structural motifs involved in 7TM signalling of adhesion GPCRs ACS Pharmacol. Transl. Sci. 2019 ORF Clones RC223172
ADK Dynamic compartmentalization of purine nucleotide metabolic enzymes at leading edge in highly motile renal cell carcinoma Biochem. Biophys. Res. Commun. 2019 ORF Clones RC200628
ADNP Interaction between FMDV L(pro) and transcription factor ADNP is required for optimal viral replication Virology 2017 ORF Clones RC209788
ADORA1 Diminished Adenosine A1 Receptor Expression in Pancreatic a-Cells May Contribute to the Pathology of Type 1 Diabetes Diabetes 4208-19 Nov 2013 ORF Clones RG222013
ADORA3 Probing structure-activity relationship in β-arrestin2 recruitment of diversely substituted adenosine derivatives Biochem. Pharmacol. 2018 ORF Clones RC206508
ADPGK ADP-dependent glucokinase regulates energy metabolism via ER-localized glucose sensing Sci Rep 2019 ORF Clones RG202965
Adra1d Pannexin 1 Channels as an Unexpected New Target of the Anti-Hypertensive Drug Spironolactone Circ. Res. 2017 ORF Clones MR222643
ADRA1D A quantized mechanism for activation of pannexin channels Nat Commun 2017 ORF Clones MR222643
ADRA1D A molecular signature in the pannexin1 intracellular loop confers channel activation by the a1 adrenoreceptor in smooth muscle cells Sci Signal Feb 2015 ORF Clones MR222643
ADRB2 Acoustofluidic Chemical Waveform Generator and Switch Anal. Chem. Nov 2014 ORF Clones RG204499
ADRB2 Divergent Label-free Cell Phenotypic Pharmacology of Ligands at the Overexpressed β2-Adrenergic Receptors Sci Rep, Jan 2014. ORF Clones SC116997
ADRB3 Adipocyte β-arrestin-2 is essential for maintaining whole body glucose and energy homeostasis Nat Commun 2019 ORF Clones MR225687
ADRB3 β3 -adrenergic receptor activation plays an important role in the depressed myocardial contractility via both elevated levels of cellular free Zn2+ and reactive nitrogen species J. Cell. Physiol. 2019 ORF Clones RR205205
ADRB3 Differential S-palmitoylation of the human and rodent β3-adrenergic receptor J. Biol. Chem. 2018 ORF Clones RC210428
ADRBK1 Agonist-selective NOP receptor phosphorylation correlates in vitro and in vivo and reveals differential post-activation signaling by chemically diverse agonists Sci Signal 2019 ORF Clones RC210327
ADRBK1 The ubiquitin ligase Mdm2 controls oligodendrocyte maturation by intertwining mTOR with G protein-coupled receptor kinase 2 in the regulation of GPR17 receptor desensitization Glia Jul 2015 ORF Clones RC210327
ADRM1 Single Live Cell Monitoring of Protein Turnover Reveals Intercellular Variability and Cell-Cycle Dependence of Degradation Rates Mol. Cell 2018 ORF Clones MR206404
AEBP1 Aortic carboxypeptidase-like protein, a WNT ligand, exacerbates nonalcoholic steatohepatitis J. Clin. Invest. 2018 ORF Clones MR211674
AFF3 Combined transcriptome studies identify AFF3 as a mediator of the oncogenic effects of ß-catenin in adrenocortical carcinoma Oncogenesis Jul 2015 ORF Clones RC221621
AFF4 Clinical and molecular spectrum of CHOPS syndrome Am. J. Med. Genet. A 2019 ORF Clones RC217692
AFF4 Germline gain-of-function mutations in AFF4 cause a developmental syndrome functionally linking the super elongation complex and cohesin Nat. Genet. Apr 2015 ORF Clones RC217692
AFP Modulation of miR-29 expression by alpha-fetoprotein is linked to the hepatocellular carcinoma epigenome Hepatology May 2014 ORF Clones RC206622
AGAP2 Role of AGAP2 in the profibrogenic effects induced by TGFβ in LX-2 hepatic stellate cells Biochim Biophys Acta Mol Cell Res 2019 ORF Clones RC206993
AGBL2 Tumor suppressor RARRES1 links tubulin deglutamylation to mitochondrial metabolism and cell survival Oncotarget 2019 ORF Clones RC206949
Ager Defective Interplay Between mTORC1 Activity and Endoplasmic Reticulum Stress-Unfolded Protein Response in Uremic Vascular Calcification Am. J. Physiol. Renal Physiol. 2018 ORF Clones MR206306
AGER Nitration and glycation turn mature NGF into a toxic factor for motor neurons: a role for p75NTR and RAGE signaling in ALS Antioxid. Redox Signal. 2017 ORF Clones RC204664
AGO1 Dysregulation of a family of short noncoding RNAs, tsRNAs, in human cancer Proc. Natl. Acad. Sci. U.S.A. Apr 2016 ORF Clones RC209163
AGO2 An alternative microRNA-mediated post-transcriptional regulation of GADD45A by p53 in human non-small-cell lung cancer cells Sci Rep 2017 ORF Clones RC218078
AGO2 Dysregulation of a family of short noncoding RNAs, tsRNAs, in human cancer Proc. Natl. Acad. Sci. U.S.A. Apr 2016 ORF Clones RC218078
AGPAT1 The role of N-terminal segment and membrane association in MyD88-mediated signaling Biochem. Biophys. Res. Commun.2017 ORF Clones RC210304
AGR2 RAD9A promotes metastatic phenotypes through transcriptional regulation of Anterior Gradient 2 (AGR2) Carcinogenesis 2018 ORF Clones RC202023
AGRN Ephrin-B3 binds both cell-associated and secreted proteoglycans Biochem. Biophys. Res. Commun. 2018 ORF Clones RC212203
AGT Molecular mechanisms of brain-ras hyperactivity upon fluid balance, and sufficiency of angiotensin production from the subfornical organ to affect fluid balance Thesis May 2015 ORF Clones RC203768
AGTR1 Differential Contribution of Transmembrane Domains IV, V, VI, and VII to Human Angiotensin II Type 1 Receptor Homomer Formation J. Biol. Chem 2017 ORF Clones RC209773
AGTR1 The renin angiotensin system (RAS) mediates bifunctional growth regulation in melanoma and is a novel target for therapeutic intervention Oncogene 2018 ORF Clones RC209773
AGTR1 Intracrine action of angiotensin II in mesangial cells: subcellular distribution of angiotensin II receptor subtypes AT1and AT2 Mol. Cell. Biochem. 2018 ORF Clones RC209773
AGTR1 Trichostatin A Modulates Angiotensin II-induced Vasoconstriction and Blood Pressure Via Inhibition of p66shc Activation Korean J. Physiol. Pharmacol. Sep 2015 ORF Clones RC209773
AGTR1 The Angiotensin II Type 1 Receptor (AT1R) Closely Interacts with BK Channels and Inhibits their Activity Independent of G-protein Activation J. Biol. Chem. July 2014 ORF Clones RC212008
AGTR1A Sniffer cells for the detection of neural Angiotensin II in vitro Sci Rep 2019 ORF Clones RR215252
Agtr1a Caveolin-1 Prevents Sustained Angiotensin II-induced Resistance Artery Constriction and Obesity-induced High Blood Pressure Am. J. Physiol. Heart Circ. Physiol. Dec 2014 ORF Clones RR215252
AGTR1A Proximal tubule-dominant transfer of AT1a receptors induces blood pressure responses to intracellular angiotensin II in AT1a receptor-deficient mice Am J Physiol Regulatory Integrative Comp Physiol, Apr 2013; 304: R588 - R598. ORF Clones MG205480
AGTR2 Intracrine action of angiotensin II in mesangial cells: subcellular distribution of angiotensin II receptor subtypes AT1and AT2 Mol. Cell. Biochem. 2018 ORF Clones RC223317
AGTR2 Trichostatin A Modulates Angiotensin II-induced Vasoconstriction and Blood Pressure Via Inhibition of p66shc Activation Korean J. Physiol. Pharmacol. Sep 2015 ORF Clones RC223317
AGTRAP The Angiotensin Receptor-associated Protein Atrap is a Stimulator of the Cardiac Ca2+-ATPase SERCA2a Cardiovasc. Res. Mar 2016 ORF Clones RC212155
AHR The aryl hydrocarbon receptor is a novel negative regulator of interleukin-17-mediated signaling and inflammation in vitro FEBS Lett. 2019 ORF Clones RC209832
AHR DNA methyltransferase inhibitor 5'-azacytidine ameliorates autoimmune arthritis in mice Arthritis & rheumatology (Hoboken, N.J.) 2019 ORF Clones RC209832
AHR A splicing mutation in Aryl Hydrocarbon Receptor associated with retinitis pigmentosa Hum. Mol. Genet. 2018 ORF Clones RC209832
AHR Tumor-Repopulating Cells Induce PD-1 Expression in CD8+T Cells by Transferring Kynurenine and AhR Activation Cancer Cell 2018 ORF Clones MR227590
AHR Blockade of IDO-kynurenine-AhR metabolic circuitry abrogates IFN-γ-induced immunologic dormancy of tumor-repopulating cells Nat Commun 2017 ORF Clones RC209832
AHR Methylated Pentavalent Arsenic Metabolites are Bifunctional Inducers as they Induce Cytochrome P450 1A1 (CYP1A1) and NAD(P)H: quinone oxidoreductase (NQO1) through AhR and Nrf2 dependent mechanisms Free Radic Biol Med. 2013 Oct 24. pii: S0891-5849(13)01477-9 ORF Clones RG209832
AHSA1 Hsp90 C-terminal Inhibitors Exhibit Anti-migratory Activity by Disrupting the Hsp90a/Aha1 Complex in PC3-MM2 Cells ACS Chem. Biol. Nov 2014 ORF Clones RG201782
AICDA The RNA-binding protein ROD1/PTBP3 cotranscriptionally defines AID-loading sites to mediate antibody class switch in mammalian genomes Cell Res. 2018 ORF Clones MR227286
AICDA Krüppel Like Factor 4 Promoter Undergoes Active Demethylation during Monocyte/Macrophage Differentiation PLoS ONE e93362 9 4. April 2014 ORF Clones RC202949
AIF1 The Role of Allograft Inflammatory Factor-1 in the Effects of Experimental Diabetes on B Cell Functions in the Heart Front Cardiovasc Med 2018 ORF Clones RG203154
AIF1L AIF1L regulates actomyosin contractility and filopodial extensions in human podocytes PLoS ONE 2018 ORF Clones RC215825
AIFM1 [PROVISIONAL] Whole exome sequencing identifies a novel variant in an apoptosis-inducing factor gene associated with X-linked recessive hearing loss in a Chinese Family Genet. Mol. Biol. 2019 ORF Clones RG224064
AIM2 Differential Roles for the Interferon-Inducible IFI16 and AIM2 Innate Immune Sensors for Cytosolic DNA in Cellular Senescence of Human Fibroblasts Mol. Cancer Res., May 2011; 9: 589 - 602 ORF Clones RC203120
AIRE PRKDC mutations associated with immunodeficiency, granuloma, and autoimmune regulator-dependent autoimmunity J. Allergy Clin. Immunol. Apr 2015 ORF Clones RC213497
AJAP1 MiR-552 promotes the proliferation, migration and EMT of hepatocellular carcinoma cells by inhibiting AJAP1 expression J. Cell. Mol. Med. 2019 ORF Clones RC223102
AJUBA Ajuba overexpression regulates mitochondrial potential and glucose uptake through YAP/Bcl-xL/GLUT1 in human gastric cancer Gene 2019 ORF Clones RC215384
AKAP1 Depletion of dAKAP1-protein kinase A signaling islands from the outer mitochondrial membrane alters breast cancer cell metabolism and motility J. Biol. Chem. 2018 ORF Clones RC200506
AKAP12 SSeCKS/Gravin/AKAP12 Inhibits PKCζ-Mediated Reduction of ERK5 Transactivation to Prevent Endotoxin-Induced Vascular dysfunction Cardiovasc. Toxicol. 2019 ORF Clones MR216222
AKAP4 A-Kinase Anchoring Protein 4 (AKAP4) is an ERK1/2 substrate and a switch molecule between cAMP/PKA and PKC/ERK1/2 in human spermatozoa Sci Rep 2016 ORF Clones RG221765
AKAP6 Human muscle-specific A-kinase anchoring protein (mAKAP) polymorphisms modulate the susceptibility to cardiovascular diseases by altering cAMP/ PKA signaling Am. J. Physiol. Heart Circ. Physiol. 2018 ORF Clones RC215986
AKAP6 SRY-box 9 (SOX9): A Novel Binding Partner of Cardiac Muscle-specific A-Kinase Anchoring Protein (mAKAP) Signalosome The FASEB Journal 2017 ORF Clones RC215986
AKIRIN2 A critical role for the nuclear protein Akirin2 in the formation of mammalian muscle in vivo Genesis 2019 ORF Clones MR219891
AKR1A1 Pathways of retinoid synthesis in mouse macrophages and bone marrow cells J. Leukoc. Biol. Jan 2016 ORF Clones MR204727
AKR1B1 Asthma and allergic rhinitis associate with the rs2229542 variant that induces a p.Lys90Glu mutation and compromises AKR1B1 protein levels Hum. Mutat. 2018 ORF Clones RC200504
AKR1B8 The Evf2 Ultraconserved Enhancer lncRNA Functionally and Spatially Organizes Megabase Distant Genes in the Developing Forebrain Mol. Cell 2018 ORF Clones MR204542
AKR1B8 Pathways of retinoid synthesis in mouse macrophages and bone marrow cells J. Leukoc. Biol. Jan 2016 ORF Clones MR204542
AKR1C1 The roles of AKR1C1 and AKR1C2 in ethyl-3,4-dihydroxybenzoate induced esophageal squamous cell carcinoma cell death Oncotarget 2016 ORF Clones RC207278
AKR1C2 Up-Regulated AKR1C2 is correlated with favorable prognosis in thyroid carcinoma journal of cancer 2019 ORF Clones RC213538
AKR1C2 Hydroxytriazole derivatives as potent and selective aldo-keto reductase 1C3 inhibitors discovered by bioisosteric scaffold hopping approach European Journal of Medicinal Chemistry 2017 ORF Clones RC213538
AKT1 Akt Protein Kinase, miR-200/miR-182 Expression and Epithelial-Mesenchymal Transition Proteins in Hibernating Ground Squirrels Front Mol Neurosci 2018 ORF Clones RC220257
AKT1 SIRT1 contributes to neuroendocrine differentiation of prostate cancer Oncotarget 2018 ORF Clones RC220257
AKT1 The enhancement of combination of berberine and metformin in inhibition of DNMT1 gene expression through interplay of SP1 and PDPK1 J. Cell. Mol. Med. 2017 ORF Clones RG220257
AKT1 Dissection and integration of the autophagy signaling network initiated by bluetongue virus infection: crucial candidates ERK1/2, Akt and AMPK Sci Rep Mar 2016 ORF Clones MR207696
AKT1 Concurrent Targeting of KRAS and AKT by MiR-4689 Is a Novel Treatment Against Mutant KRAS Colorectal Cancer Mol Ther Nucleic Acids Mar 2015 ORF Clones RC220257
AKT1 AKT1E17K mutations cluster with meningothelial and transitional meningiomas and can be detected by SFRP1 immunohistochemistry Acta Neuropathol. 2013 Nov;126(5):757-62 ORF Clones RC400163
AKT2 Akt Protein Kinase, miR-200/miR-182 Expression and Epithelial-Mesenchymal Transition Proteins in Hibernating Ground Squirrels Front Mol Neurosci 2018 ORF Clones RC217733
AKT3 Upregulation of miR-582-5p regulates cell proliferation and apoptosis by targeting AKT3 in human endometrial carcinoma Saudi Journal of Biological Sciences 2018 ORF Clones RC224750
AKTIP The telomeric protein AKTIP interacts with A- and B-type lamins and is involved in regulation of cellular senescence Open Biol 2016 ORF Clones RC210569
AKTIP AKTIP/Ft1, a New Shelterin-Interacting Factor Required for Telomere Maintenance PLoS Genet. Jun 2015 ORF Clones RC210569
ALAD Involvement of ALAD-20S Proteasome Complexes in Ubiquitination and Acetylation of Proteasomal a2 Subunits J. Cell. Biochem 2016 ORF Clones RC201545
ALDH1A1 Complex Behavior of ALDH1A1 and IGFBP1 in Liver Metastasis from a Colorectal Cancer PLoS ONE May 2016 ORF Clones RC200723
ALDH1A2 Tracing Tumor Evolution in Sarcoma Reveals Clonal Origin of Advanced Metastasis Cell Rep 2019 ORF Clones MR208298
ALDH3A2 Exosomes mediate the cell-to-cell transmission of IFN-a-induced antiviral activity Nature Immunology 14, 793-803 doi:10.1038/ni.2647 ORF Clones RC200648
ALDH3B1 Pathways of retinoid synthesis in mouse macrophages and bone marrow cells J. Leukoc. Biol. Jan 2016 ORF Clones MR207483
ALDH7A1 Pathways of retinoid synthesis in mouse macrophages and bone marrow cells J. Leukoc. Biol. Jan 2016 ORF Clones MR208207
ALDH8A1 Pathways of retinoid synthesis in mouse macrophages and bone marrow cells J. Leukoc. Biol. Jan 2016 ORF Clones MR207802
ALDH9A1 Pathways of retinoid synthesis in mouse macrophages and bone marrow cells J. Leukoc. Biol. Jan 2016 ORF Clones MR207926
ALDOB Aldolase B-Mediated Fructose Metabolism Drives Metabolic Reprogramming of Colon Cancer Liver Metastasis Cell Metabolism 2018 ORF Clones RG220062
ALDOC Two Chronic Stress Models Based on Movement Restriction in Rats Respond Selectively to Antidepressant Drugs: Aldolase C As a Potential Biomarker Int. J. Neuropsychopharmacol. Mar 2015 ORF Clones RR200828
ALDOC Two chronic stress models based on movement restriction in rats respond selectively toantidepressant drugs: Aldolase C as a potential biomarker International Journal of Neuropsychopharmacology Mar 2015 ORF Clones RR200828
ALG1 ALG1-CDG: Clinical and Molecular Characterization of 39 Unreported Patients Hum. Mutat. Mar 2016 ORF Clones RC206343
ALG2 O-GlcNAcylation regulates endoplasmic reticulum exit sites through Sec31A modification in conventional secretory pathway The FASEB Journal 2018 ORF Clones RC204766
ALKBH3 Human ALKBH3-induced m1A demethylation increases the CSF-1 mRNA stability in breast and ovarian cancer cells Biochim Biophys Acta Gene Regul Mech 2018 ORF Clones RC212873
ALOX12 12-Lipoxygenase Regulates Cold Adaptation and Glucose Metabolism by Producing the Omega-3 Lipid 12-HEPE from Brown Fat Cell Metab. 2019 ORF Clones MR227302
ALOX5 GSDMB induces an asthma phenotype characterized by increased airway responsiveness and remodeling without lung inflammation Proc. Natl. Acad. Sci. U.S.A. 2016 ORF Clones RG217259
ALOX5 MerTK cleavage limits proresolving mediator biosynthesis and exacerbates tissue inflammation Proc. Natl. Acad. Sci. U.S.A. May 2016 ORF Clones RG217259
ALPPL2 Anastrozole Aromatase Inhibitor Plasma Drug Concentration Genome-Wide Association Study: Functional Epistatic Interaction between SLC38A7 and ALPPL2 Clin. Pharmacol. Ther. 2019 ORF Clones RC204330
ALPPL2 Identification of a Metabolizing Enzyme in Human Kidney by Proteomic Correlation Profiling Mol. Cell. Proteomics, Aug 2013; 12: 2313 - 2323. ORF Clones RC204330
ALYREF The chromatin remodeling complex NURF localizes to gene bodies and is required for mRNA processing J. Biol. Chem. 2018 ORF Clones MR220236
ALYREF 5-methylcytosine promotes mRNA export - NSUN2 as the methyltransferase and ALYREF as an m(5)C reader Cell Res. 2017 ORF Clones RC229136
ALYREF 5-methylcytosine promotes mRNA export - NSUN2 as the methyltransferase and ALYREF as an m(5)C reader Cell Res. 2017 ORF Clones RG229136
AMBRA1 HIV-host interactome revealed directly from infected cells Nat Microbiol 2016 ORF Clones RC206255
AMBRA1 HIV–host interactome revealed directly from infected cells Nature microbiology May 2016 ORF Clones RC206255
AMELX Surf4 (Erv29p) binds amino-terminal tripeptide motifs of soluble cargo proteins with different affinities, enabling prioritization of their exit from the endoplasmic reticulum PLoS Biol. 2018 ORF Clones RC215582
AMFR Melanoblast transcriptome analysis reveals novel pathways promoting melanoma metastasis bioRxiv 2019 ORF Clones RG209639
AMFR SVIP regulates Z variant alpha-1 antitrypsin retro-translocation by inhibiting ubiquitin ligase gp78 PLoS ONE 2017 ORF Clones RC209639
AMMECR1 AMMECR1: a single point mutation causes developmental delay, midface hypoplasia and elliptocytosis J. Med. Genet. 2016 ORF Clones RG212378
AMN Amnionless-mediated glycosylation is crucial for cell surface targeting of cubilin in renal and intestinal cells Sci Rep 2018 ORF Clones RC219248
AMOT Conditional knockout of TFPI-1 in VSMCs of mice accelerates atherosclerosis by enhancing AMOT/YAP pathway Int. J. Cardiol. 2016 ORF Clones RC226319
AMOT Angiomotin decreases lung cancer progression by sequestering oncogenic YAP/TAZ and decreasing Cyr61 expression Oncogene Nov 2014 ORF Clones RC226319
AMOTL1 Using human sequencing to guide craniofacial research. bioRxiv 2018 ORF Clones RC207693
AMOTL2 Phosphorylation of the Hippo Pathway Component AMOTL2 by mTORC2 Promotes YAP Signaling Resulting in Enhanced Glioblastoma Growth and Invasiveness J. Biol. Chem. May 2015 ORF Clones RC219781
AMPD1 Dynamic compartmentalization of purine nucleotide metabolic enzymes at leading edge in highly motile renal cell carcinoma Biochem. Biophys. Res. Commun. 2019 ORF Clones MR220907
AMPK2 Fyn phosphorylates AMPK to inhibit AMPK activity and AMP-dependent activation of autophagy Oncotarget 2016 ORF Clones RC210226
AMY2B Experimental validation of predicted subcellular localizations of human proteins BMC Res Notes Dec 2014 ORF Clones RG203812
ANG Stress-induced tRNA cleavage and tiRNA generation in rat neuronal PC12 cells J. Neurochem. 2018 ORF Clones RC208874
ANGPT1 Angiopoietin-1 haploinsufficiency affects the endothelial barrier and causes hereditary angioedema Clin. Exp. Allergy 2019 ORF Clones RC219398
ANGPT1 Structural basis for angiopoietin-1–mediated signaling initiation PNAS, Apr 2013; 110: 7205 - 7210. ORF Clones RC219398
ANGPT2 Structural basis for angiopoietin-1–mediated signaling initiation PNAS, Apr 2013; 110: 7205 - 7210. ORF Clones RC225727
ANGPTL1 The effects of farnesoid X receptor activation on arachidonic acid metabolism, NF-kB signaling and hepatic inflammation Mol. Pharmacol. 2018 ORF Clones MR20784
ANGPTL2 Angiopoietin Like Protein 2 (ANGPTL2) Promotes Adipose Tissue Macrophage and T lymphocyte Accumulation and Leads to Insulin Resistance PLoS ONE Jul 2015 ORF Clones RC201917
ANGPTL7 CD11b(+) myeloid cells support hepatic metastasis through downregulation of Angiopoietin-like 7 in cancer cells Hepatology Apr 2015 ORF Clones MR205028
ANKLE2 LEM4 confers tamoxifen resistance to breast cancer cells by activating cyclin D-CDK4/6-Rb and ERα pathway Nat Commun 2018 ORF Clones RC216867
ANKRD1 ANKRD1 regulates innate immune responses against herpes simplex virus 1: A potential role in eczema herpeticum J. Allergy Clin. Immunol. 2018 ORF Clones RC205609
ANKRD1 ANKRD1 modulates inflammatory responses IN C2C12 myoblasts through feedback inhibition OF NF-?B signaling activity Biochem. Biophys. Res. Commun. Jun 2015 ORF Clones RC205609
ANKRD1 Inhibition of ANKRD1 sensitizes human ovarian cancer cells to endoplasmic reticulum stress-induced apoptosis Oncogene, Feb 2014. ORF Clones RC205609
ANKRD22 ANKRD22 is involved in the progression of prostate cancer Oncol Lett 2019 ORF Clones RC204797
ANKRD55 Interactome of the Autoimmune Risk Protein ANKRD55 Front. Immunol. 2019 ORF Clones RC221211
ANKS3 Crystal Structure of Bicc1 SAM Polymer and Mapping of Interactions between the Ciliopathy-Associated Proteins Bicc1, ANKS3, and ANKS6 Structure 2017 ORF Clones RC223862
ANKZF1 MISTERMINATE Mechanistically Links Mitochondrial Dysfunction with Proteostasis Failure bioRxiv 2019 ORF Clones RC201054
ANKZF1 Vms1 and ANKZF1 peptidyl-tRNA hydrolases release nascent chains from stalled ribosomes Nature 2018 ORF Clones RC201054
ANO1 CLCA2 is a positive regulator of store-operated calcium entry and TMEM16A PLoS ONE 2018 ORF Clones RC229400
ANO1 TMEM16A mediates the hypersecretion of mucus induced by Interleukin-13 Exp. Cell Res. Mar 2015 ORF Clones RC229400
ANO1 TMEM16A protein attenuates lipopolysaccharide-mediated inflammatory response of human lung epithelial cell line A549 Exp. Lung Res. Jun 2014 ORF Clones RC229400
ANO2 Ani9, A Novel Potent Small-Molecule ANO1 Inhibitor with Negligible Effect on ANO2 PLoS ONE May 2016 ORF Clones RC222601
ANPEP Identification of residues controlling restriction versus enhancing activities of IFITM proteins on the entry of human coronaviruses J. Virol. 2017 ORF Clones RC208950
ANXA1 Genetic modifiers of muscular dystrophy act on sarcolemmal resealing and recovery from injury PLoS Genet. 2017 ORF Clones RG201569
ANXA1 Intermittent Glucocorticoid Dosing Improves Muscle Repair and Function in Mice with Limb Girdle Muscular Dystrophy Am. J. Pathol. 2017 ORF Clones RG201569
Anxa1 An actin-dependent annexin complex mediates plasma membrane repair in muscle J. Cell Biol. Jun 2016 ORF Clones MG205210
ANXA1 Annexin A1 Complex Mediates Oxytocin Vesicle Transport J Neuroendocrinol. 2013 Oct 3 ORF Clones RG201569
ANXA10 Cul4A Modulates Invasion and Metastasis of Lung Cancer Through Regulation of ANXA10 Cancers (Basel) 2019 ORF Clones RG200268
ANXA10 ANXA10 induction by interaction with tumor-associated macrophages promotes the growth of esophageal squamous cell carcinoma Pathol. Int. 2019 ORF Clones RC200268
ANXA10 Simvastatin Up-Regulates Annexin A10 That Can Inhibit the Proliferation, Migration, and Invasion in Androgen-Independent Human Prostate Cancer Cells The Prostate 2016 ORF Clones RC200268
Anxa11 An actin-dependent annexin complex mediates plasma membrane repair in muscle J. Cell Biol. Jun 2016 ORF Clones MG225524
ANXA2 Curvature- and Phase-Induced Protein Sorting Quantified in Transfected Cell-Derived Giant Vesicles ACS Nano 2019 ORF Clones RG205081
ANXA2 Cancer-associated fibroblasts promote epithelial-mesenchymal transition and EGFR-TKI resistance of non-small cell lung cancers via HGF/IGF-1/ANXA2 signaling Biochim. Biophys. Acta 2017 ORF Clones RC205081
Anxa2 An actin-dependent annexin complex mediates plasma membrane repair in muscle J. Cell Biol. Jun 2016 ORF Clones MG205064
ANXA4 Curvature- and Phase-Induced Protein Sorting Quantified in Transfected Cell-Derived Giant Vesicles ACS Nano 2019 ORF Clones RG203229
ANXA5 Annexin A5 regulates surface αvβ5 integrin for retinal clearance phagocytosis J. Cell. Sci. 2019 ORF Clones RC205619
ANXA5 Curvature- and Phase-Induced Protein Sorting Quantified in Transfected Cell-Derived Giant Vesicles ACS Nano 2019 ORF Clones RG205619
ANXA5 Annexin A5 inhibits diffuse large B-cell lymphoma cell invasion and chemoresistance through phosphatidylinositol 3-kinase signaling Oncol. Rep. Dec 2014 ORF Clones RC205619
ANXA5 Annexin A5 promotes invasion and chemoresistance to temozolomide in glioblastoma multiforme cells Tumour Biol. Sep 2014 ORF Clones RC205619
ANXA5 An SRF/miR-1 axis regulates NCX1 and Annexin A5 protein levels in the normal and failing heart Cardiovasc Res, Jun 2013; 98: 372 - 380. ORF Clones RG205619
ANXA6 Inhibition of somatosensory mechanotransduction by annexin A6 Sci Signal 2018 ORF Clones RC202086
ANXA6 Liprotides kill cancer cells by disrupting the plasma membrane Sci Rep 2017 ORF Clones RG202086
ANXA6 Human Annexin A6 Interacts with Influenza A Virus Protein M2 and Negatively Modulates Infection J. Virol., Feb 2012; 86: 1789 - 1801. ORF Clones RC202086
AP1M1 Murine leukemia virus glycosylated Gag reduces murine SERINC5 protein expression at steady-state levels via endosome/lysosome pathway to counteract the SERINC5 antiretroviral activity J. Virol. 2018 ORF Clones RC202366
AP1M1 HIV-1 Nef antagonizes SERINC5 restriction by downregulation of SERINC5 via the endosome/lysosome system J. Virol. 2018 ORF Clones RC202366
AP2A1 µ2-Dependent Endocytosis of N-cadherin Is Regulated by ß-Catenin to Facilitate Neurite Outgrowth Traffic 2017 ORF Clones RR208798
AP2B1 µ2-Dependent Endocytosis of N-cadherin Is Regulated by ß-Catenin to Facilitate Neurite Outgrowth Traffic 2017 ORF Clones RR209156
AP2M1 µ2-Dependent Endocytosis of N-cadherin Is Regulated by ß-Catenin to Facilitate Neurite Outgrowth Traffic 2017 ORF Clones RR212640
AP2S1 Targeting F-Box Protein Fbxo3 Attenuates Lung Injury Induced by Ischemia-Reperfusion in Rats Front Pharmacol 2019 ORF Clones RG223424
AP2S1 ASTN2 modulates synaptic strength by trafficking and degradation of surface proteins bioRxiv 2018 ORF Clones MR200768
APAF1 MicroRNA-23a/b and microRNA-27a/b suppress Apaf-1 protein and alleviate hypoxia-induced neuronal apoptosis Cell Death Dis Mar 2014 ORF Clones RC213433
APBB1 Fe65 Is Phosphorylated on Ser289 after UV-Induced DNA Damage PLoS ONE May 2016 ORF Clones RC202003
APBB1 Fe65 Ser228 is Phosphorylated by ATM/ATR and Inhibits Fe65-APP-Mediated Gene Transcription Biochem. J. Nov 2014 ORF Clones RC202003
APC Molecular Characterization of Somatic Alterations in Dukes' B and C Colorectal Cancers by Targeted Sequencing Front Pharmacol 2017 ORF Clones RC226492
APC MicroRNA-210 Enhances Fibrous Cap Stability in Advanced Atherosclerotic Lesions Circ. Res 2016 ORF Clones RG226492
APLN Apelin promotes hepatic fibrosis through ERK signaling in LX-2 cells Mol. Cell. Biochem. 2019 ORF Clones RC205832
APLNR MicroRNA 139-5p coordinates APLNR-CXCR4 crosstalk during vascular maturation Nat Commun Apr 2016 ORF Clones RG207576
APLP1 APLP1 and APLP2, members of the app family of proteins, behave similarly to app in that they associate with nmda receptors and enhance nmda receptor surface expression J. Neurochem. Feb 2015 ORF Clones RC215282
APLP2 APLP1 and APLP2, members of the app family of proteins, behave similarly to app in that they associate with nmda receptors and enhance nmda receptor surface expression J. Neurochem. Feb 2015 ORF Clones RC226552
APOBEC1 A Novel RNA Editing Sensor Tool and a Specific Agonist Determine Neuronal Protein Expression of RNA-Edited Glycine Receptors and Identify a Genomic APOBEC1 Dimorphism as a New Genetic Risk Factor of Epilepsy Front Mol Neurosci 2017 ORF Clones RC215744
APOBEC3A Transient overexpression of exogenous APOBEC3A causes C-to-U RNA editing of thousands of genes RNA Biol May 2016 ORF Clones RC220995
APOBEC3A APOBEC3A cytidine deaminase induces RNA editing in monocytes and macrophages Nat Commun Apr 2015 ORF Clones RC220995
APOBEC3A APOBEC3A Is Implicated in a Novel Class of G-to-A mRNA Editing in WT1 Transcripts PLoS ONE Mar 2015 ORF Clones RG220995
APOC3 A human APOC3 missense variant and monoclonal antibody accelerate apoC-III clearance and lower triglyceride-rich lipoprotein levels Nat. Med.2017 ORF Clones RC206566
APOD Apolipoprotein D Upregulation in Alzheimer's Disease but Not Frontotemporal Dementia J. Mol. Neurosci. 2018 ORF Clones RC200503
APOE SFRS11 Loss Leads to Aging-Associated Cognitive Decline by Modulating LRP8 and ApoE Cell Rep 2019 ORF Clones RC200395
APOE Human ApoE Isoforms Differentially Modulate Brain Glucose and Ketone Body Metabolism: Implications for Alzheimer's Disease Risk Reduction and Early Intervention J. Neurosci. 2018 ORF Clones RC200395
APOL1 Recruitment of APOL1 kidney disease risk variants to lipid droplets attenuates cell toxicity Proc. Natl. Acad. Sci. U.S.A. 2019 ORF Clones RC211114
APOL1 APOL1-G1 in Nephrocytes Induces Hypertrophy and Accelerates Cell Death J. Am. Soc. Nephrol. 2016 ORF Clones RC211114
APOL1 Regulation of Fluid-phase Uptake in Podocytes by Albumin-associated Lipids Thesis Sep 2014 ORF Clones RG211114
APP IRX5 regulates adipocyte amyloid precursor protein and mitochondrial respiration in obesity Int J Obes (Lond) 2018 ORF Clones MR210090
APP Kinesin-1 proteins KIF5A, 5B and 5C promote anterograde transport of herpes simplex virus enveloped virions in axons J. Virol. 2018 ORF Clones RG215147
APP Human Umbilical Cord Blood Serum-derived α-Secretase: Functional Testing in Alzheimer's Disease Mouse Models Cell Transplant 2018 ORF Clones RC215147
APP HIV-1 counteracts an innate restriction by amyloid precursor protein resulting in neurodegeneration Nat Commun 2017 ORF Clones RC209575
APP Excess APP O-glycosylation by GalNAc-T6 decreases Aß production The Journal of Biochemistry 2016 ORF Clones RC215147
Appl1 The E3 ubiquitin ligase RNF114 and TAB1 degradation are required for maternal-to-zygotic transition EMBO Rep 2017 ORF Clones MR210175
APPL1 Loss-of-Function Mutations in APPL1 in Familial Diabetes Mellitus AJHG Jul 2015 ORF Clones RC206021
APQ4 Anti-aquaporin-1 autoantibodies in patients with neuromyelitis optica spectrum disorders PLoS One. 2013 Sep 23;8(9):e74773 ORF Clones RG204693
APRT Dynamic compartmentalization of purine nucleotide metabolic enzymes at leading edge in highly motile renal cell carcinoma Biochem. Biophys. Res. Commun. 2019 ORF Clones RC216874
APTX XRCC1 phosphorylation affects aprataxin recruitment and DNA deadenylation activity DNA Repair (Amst.) 2018 ORF Clones MG218020
AQP1 Genome Engineering Renal Epithelial Cells for Enhanced Volume Transport Function Cellular and Molecular Bioengineering 2019 ORF Clones RC205304
AQP1 Non-invasive imaging using reporter genes altering cellular water permeability Nat Commun 2016 ORF Clones RC205304
AQP1 Comparative Analysis for the Presence of IgG Anti-Aquaporin-1 in Patients with NMO-Spectrum Disorders Int J Mol Sci 2016 ORF Clones RG205304
AQP1 Anti-aquaporin-1 autoantibodies in patients with neuromyelitis optica spectrum disorders PLoS One. 2013 Sep 23;8(9):e74773 ORF Clones RG205304
AQP11 Human aquaporin-11 guarantees efficient transport of H2O2 across the endoplasmic reticulum membrane Redox Biol 2019 ORF Clones RC208083
AQP11 A persulfidation-based mechanism controls aquaporin-8 conductance Sci Adv 2018 ORF Clones RC208083
AQP3 Identification of Estrogen Response Element in Aquaporin-3 Gene that Mediates Estrogen-induced Cell Migration and Invasion in Estrogen Receptor-positive Breast Cancer Sci Rep Jul 2015 ORF Clones RC201856
AQP4 Non-invasive imaging using reporter genes altering cellular water permeability Nat Commun 2016 ORF Clones RC204693
AQP4 Detection of aquaporin-4 antibody status of Thai patients with neuromyelitis optica spectrum disorders using a recombinant Escherichia coli aquaporin-4 enzyme-linked immunosorbent assay Clinical and Experimental Neuroimmunology Oct 2014 ORF Clones RG204693
AQP4 Detection of NMO-IgG Antibodies in Thai NMO Patients Using a Recombinant E. coli AQP4-M23 ELISA J Physiol July 2014 ORF Clones RG204693
AQP4 Oligodendrocytes are damaged by neuromyelitis optica immunoglobulin G via astrocyte injury Brain, Sep 2010; 133: 2578 - 2591 ORF Clones RC204693
AQP5 Pre- and Post-synaptic Effects of Botulinum Toxin A on Submandibular Glands J. Dent. Res. Jun 2015 ORF Clones RG206069
AQP8 A persulfidation-based mechanism controls aquaporin-8 conductance Sci Adv 2018 ORF Clones RG219668
AR Discovery and biological evaluation of novel androgen receptor antagonist for castration-resistant prostate cancer Eur J Med Chem 2019 ORF Clones RC235415
AR Strategy for Tumor Selective Disruption of Androgen Receptor Function in the Spectrum of Prostate Cancer Clin. Cancer Res. 2018 ORF Clones MR226737
AR Plexin-B1 signalling promotes androgen receptor translocation to the nucleus Oncogene May 2015 ORF Clones RG235415
ARAF Somatic activating ARAF mutations in Langerhans cell histiocytosis Blood Mar 2014 ORF Clones RC200737
Arc Chemogenomic analysis reveals key role for lysine acetylation in regulating Arc stability Nat Commun 2017 ORF Clones MR206218
ARD1 Acetylation and deacetylation of Cdc25A constitutes a novel mechanism for modulating Cdc25A functions with implications for cancer Oncotarget 2016 ORF Clones RC201354
ARF1 Phospholipase D2 Is Involved in the Formation of Golgi Tubules and ArfGAP1 Recruitment PLoS ONE Oct 2014 ORF Clones RG201240
ARF4 Class II ADP-ribosylation Factors Are Required for Efficient Secretion of Dengue Viruses J. Biol. Chem., Jan 2012; 287: 767 - 777. ORF Clones RC204984
ARF5 Class II ADP-ribosylation Factors Are Required for Efficient Secretion of Dengue Viruses J. Biol. Chem., Jan 2012; 287: 767 - 777. ORF Clones RC201363
Arf6 Small GTPase ARF6 Regulates Endocytic Pathway Leading to Degradation of ATP-Binding Cassette Transporter A1 Arterioscler. Thromb. Vasc. Biol. 2016 ORF Clones MG201520
Arf6 ß-Cryptoxanthin reduced lung tumor multiplicity and inhibited lung cancer cells motility by down-regulating nicotinic acetylcholine receptor a7 expression Cancer Prev Res (Phila) 2016 ORF Clones MR201520
ARG1 Arginase-I enhances vascular endothelial inflammation and senescence through eNOS-uncoupling BMC Res Notes 2017 ORF Clones MR204674
ARG1 Homoarginine and inhibition of human arginase activity: kinetic characterization and biological relevance Sci Rep 2018 ORF Clones RC204649
ARG1 Strategies to rescue the consequences of inducible arginase-1 deficiency in mice PLoS ONE May 2015 ORF Clones MG204674
ARG2 Homoarginine and inhibition of human arginase activity: kinetic characterization and biological relevance Sci Rep 2018 ORF Clones RC206756
ARHGAP24 Glucose Transporter 4 (GLUT4) is Not Necessary for Overload-Induced Glucose Uptake or Hypertrophic Growth in Mouse Skeletal Muscle Diabetes 2017 ORF Clones MR209791
ARHGAP29 Exome sequencing provides additional evidence for the involvement of ARHGAP29 in Mendelian orofacial clefting and extends the phenotypic spectrum to isolated cleft palate Birth Defects Res. Part A Clin. Mol. Teratol 2016 ORF Clones RC210830
ARHGAP30 ArhGAP30 promotes p53 acetylation and function in colorectal cancer Nat Commun Aug 2014 ORF Clones RC208825
ARHGDIA EphrinB1 promotes cancer cell migration and invasion through the interaction with RhoGDI1 Oncogene 2017 ORF Clones RC200902
ARHGDIA Differentially Expressed Proteins in ER+ MCF7 and ER- MDA- MB-231 Human Breast Cancer Cells by RhoGDI-a Silencing and Overexpression Asian Pac. J. Cancer Prev. May 2014 ORF Clones RG200902
ARHGDIB EphrinB1 promotes cancer cell migration and invasion through the interaction with RhoGDI1 Oncogene 2017 ORF Clones RC203496
ARHGEF11 HGAL, a germinal center specific protein, decreases lymphoma cell motility by modulation of the RhoA signaling pathway Blood, Dec 2010; 116: 5217 - 5227 ORF Clones RC208729
ARHGEF19 miR-503 regulates metastatic function through Rho guanine nucleotide exchanger factor 19 in hepatocellular carcinoma Journal of Surgical Research Dec 2013. ORF Clones RG202273
ARHGEF2 Microbial recognition by GEF-H1 controls IKKε mediated activation of IRF5 Nat Commun 2019 ORF Clones RC204546
ARHGEF37 ArhGEF37 assists dynamin 2 during clathrin-mediated endocytosis J. Cell. Sci. 2019 ORF Clones MG222459
ARID1A Identification and functional characterization of a novel bipartite nuclear localization sequence in ARID1A Biochem. Biophys. Res. Commun. Nov 2015 ORF Clones RC218151
ARID1A Decreased ARID1A expression facilitates cell proliferation and inhibits 5-fluorouracil-induced apoptosis in colorectal carcinoma Tumour Biol. May 2014 ORF Clones RC218151
ARID5A Profiling the Gene Expression and DNA Methylation in the Mouse Brain after Ischemic Preconditioning Neuroscience 2019 ORF Clones MR219216
ARID5A IL-17 integrates multiple self-reinforcing, feed-forward mechanisms through the RNA binding protein Arid5a Sci Signal 2018 ORF Clones MR216827
ARID5B Transposon mutagenesis reveals fludarabine-resistance mechanisms in chronic lymphocytic leukemia Clin. Cancer Res. Mar 2016 ORF Clones RC211454
ARL11 Arl11 regulates lipopolysacchride-stimulated macrophage activation by promoting MAPK signaling J. Biol. Chem. 2018 ORF Clones RC203868
ARL13B Arl13b Interacts With Vangl2 to Regulate Cilia and Photoreceptor Outer Segment Length in Zebrafish Invesitgate Ophthalmology & Visual Science 2016 ORF Clones RG221949
ARL13B Arl13b Interacts With Vangl2 to Regulate Cilia and Photoreceptor Outer Segment Length in Zebrafish Invest. Ophthalmol. Vis. Sci. 2016 ORF Clones RC221949
ARL13B A novel role for Rab23 in the trafficking of Kif17 to the primary cilium J. Cell. Sci. Jul 2015 ORF Clones MG206808
ARL15 ADP-ribosylation factor-like GTPase 15 enhances insulin-induced AKT phosphorylation in the IR/IRS1/AKT pathway by interacting with ASAP2 and regulating PDPK1 activity Biochem. Biophys. Res. Commun 2017 ORF Clones RC205610
ARL6IP6 Identification of new transmembrane proteins concentrated at the nuclear envelope using organellar proteomics of mesenchymal cells Nucleus 2019 ORF Clones MR202673
ARL6IP6 Identification of new transmembrane proteins concentrated at the nuclear envelope using organellar proteomics of mesenchymal cells bioRxiv 2018 ORF Clones MR202673
Armc10 The Armc10/SVH gene: genome context, regulation of mitochondrial dynamics and protection against Aß-induced mitochondrial fragmentation Cell Death Dis e1163 5 . April 2014 ORF Clones MR204310
ARMC5 The role of ARMC5 in human cell cultures from nodules of primary macronodular adrenocortical hyperplasia (PMAH) Mol. Cell. Endocrinol. 2017 ORF Clones RC226267
ARNT2 Integrated Systems Biology Approach Identifies Novel Maternal and Placental Pathways of Preeclampsia Front Immunol 2018 ORF Clones RG211966
Arntl The Circadian Clock Regulates Adipogenesis by a Per3 Crosstalk Pathway to Klf15 Cell Rep 2017 ORF Clones MR209553
Aro Impact of R264C and R264H polymorphisms in human aromatase function J. Steroid Biochem. Mol. Biol. 2016 ORF Clones RC205890
ARP3 Actin related protein 3 (ARP3) promotes apoptosis of intestinal epithelial cells in ulcerative colitis Pathol. Res. Pract. 2019 ORF Clones RC208460
ARPC2 ARPC2 promotes breast cancer proliferation and metastasis Oncol. Rep. 2019 ORF Clones RC200319
ARPC5 Interaction between microRNAs and actin-associated protein Arpc5 regulates translational suppression during male germ cell differentiation PNAS, Mar 2012; 10.1073/pnas.1117837109. ORF Clones RC212631
ARPIN Restoration of Arpin suppresses aggressive phenotype of breast cancer cells Biomed. Pharmacother. 2017 ORF Clones RC208793
ARRB1 miR-374a-5p promotes tumor progression by targeting ARRB1 in triple negative breast cancer Cancer Lett. 2019 ORF Clones RC201279
ARRB1 Beta-Arrestin1 Prevents Preeclampsia by Downregulation of Mechanosensitive AT1-B2 Receptor Heteromers Cell 2019 ORF Clones RC201279
ARRB1 ß-Arrestin 1-dependent regulation of Rap2 is required for fMLP-stimulated chemotaxis in neutrophil-like HL-60 cells J. Leukoc. Biol. 2016 ORF Clones RG201279
ARRB2 β-Arrestins regulate stem cell-like phenotype and response to chemotherapy in bladder cancer Mol. Cancer Ther. 2019 ORF Clones RC201168
ARRB2 Probing structure-activity relationship in β-arrestin2 recruitment of diversely substituted adenosine derivatives Biochem. Pharmacol. 2018 ORF Clones RC201168
ARRB2 Activity-Based Concept to Screen Biological Matrices for Opiates and (Synthetic) Opioids Clin. Chem. 2018 ORF Clones RC201168
ARSB Chondroitin sulfatases differentially regulate Wnt signaling in prostate stem cells through effects on SHP2, phospho-ERK1/2, and Dickkopf Wnt signaling pathway inhibitor (DKK3) Oncotarget 2017 ORF Clones RC214604
ARSG A canine Arylsulfatase G (ARSG) mutation leading to a sulfatase deficiency is associated with neuronal ceroid lipofuscinosis PNAS, Aug 2010; 107: 14775 - 14780 ORF Clones RC201967
ART3 ART3 regulates triple-negative breast cancer cell function via activation of Akt and ERK pathways Oncotarget 2016 ORF Clones RC225592
ARTN Artemin regulates CXCR4 expression to induce migration and invasion in pancreatic cancer cells through activation of NF-κB signaling Exp. Cell Res. 2018 ORF Clones RC209122
ARTN Neurotrophin selectivity in organizing topographic regeneration of nociceptive afferents Exp. Neurol. Jun 2015 ORF Clones RN209126
ARX Ascl1 and Helt act combinatorially to specify thalamic neuronal identity by repressing Dlxs activation Dev. Biol. Dec 2014 ORF Clones MG208926
ASAH1 Complete Acid Ceramidase ablation prevents cancer-initiating cell formation in melanoma cells Sci Rep 2017 ORF Clones RG212434
ASAH2 Enhanced Sphingomyelinase Activity Contributes to the Apoptotic Capacity of Electronegative Low-Density Lipoprotein J. Med. Chem. Feb 2016 ORF Clones RC215027
ASAP2 Selenoprotein K regulation of palmitoylation and calpain cleavage of ASAP2 is required for efficient Fc?R-mediated phagocytosis J. Leukoc. Biol. 2016 ORF Clones MR211308
ASCL1 Combinatorial programming of human neuronal progenitors using magnetically-guided stoichiometric mRNA delivery Elife 2018 ORF Clones RC201123
ASGR1 Inhibition of Ebola virus glycoprotein-mediated cytotoxicity by targeting its transmembrane domain and cholesterol Nat Commun Jul 2015 ORF Clones RC205686
ASIC1 Dual actions of Psalmotoxin at ASIC1a and ASIC2a heteromeric channels (ASIC1a/2a) Sci Rep 2018 ORF Clones RR207637
ASIC1 SPX-101 is a Novel ENaC-targeted Therapeutic for Cystic Fibrosis that Restores Mucus Transport Am. J. Respir. Crit. Care Med. 2017 ORF Clones RC217623
ASIC2 Dual actions of Psalmotoxin at ASIC1a and ASIC2a heteromeric channels (ASIC1a/2a) Sci Rep 2018 ORF Clones RR200428
ASIC2 SPX-101 is a Novel ENaC-targeted Therapeutic for Cystic Fibrosis that Restores Mucus Transport Am. J. Respir. Crit. Care Med. 2017 ORF Clones RC210409
ASL Silencing of argininosuccinate lyase inhibits colorectal cancer formation Oncol. Rep. 2016 ORF Clones RC201568
ASNS The GCN2-ATF4 pathway is critical for tumour cell survival and proliferation in response to nutrient deprivation The EMBO Journal (14 May 2010) doi:10.1038/emboj.2010.81 Article ORF Clones RC201297
ASPH Aspartate β-hydroxylase disrupts mitochondrial DNA stability and function in hepatocellular carcinoma Oncogenesis 2017 ORF Clones RC216796
ASPN The dual role of asporin in breast cancer progression Oncotarget 2016 ORF Clones RC209353
ASS1 Efficacy of arginine depletion by ADI-PEG20 in an intracranial model of GBM Cell Death Dis 2018 ORF Clones MR206472
ASS1 Argininosuccinate Synthetase 1 Loss in Invasive Bladder Cancer Regulates Survival through General Control Nonderepressible 2 Kinase-Mediated Eukaryotic Initiation Factor 2a Activity and Is Targetable by Pegylated Arginine Deiminase Am. J. Pathol 2016 ORF Clones RC223189
ASS1 Argininosuccinate Synthetase 1 Loss in Invasive Bladder Cancer Regulates Survival through General Control Nonderepressible 2 Kinase-Mediated Eukaryotic Initiation Factor 2α Activity and Is Targetable by Pegylated Arginine Deiminase The American Journal of Pathology 2016 ORF Clones RC223189
ASS1 Reduced argininosuccinate synthetase expression in refractory sarcomas: Impacts on therapeutic potential and drug resistance Oncotarget 2016 ORF Clones RC223189
ASS1 Argininosuccinate synthetase 1 suppression and arginine restriction inhibit cell migration in gastric cancer cell lines Sci Rep May 2015 ORF Clones RC223189
ASS1 ASS1 as a Novel Tumor Suppressor Gene in Myxofibrosarcomas: Aberrant Loss via Epigenetic DNA Methylation Confers Aggressive Phenotypes, Negative Prognostic Impact, and Therapeutic Relevance Clin. Cancer Res., Jun 2013; 19: 2861 - 2872. ORF Clones RC223189
AT1R Phosphorylation at distinct subcellular locations underlies specificity in mTORC2 activation of SGK1 and Akt J. Cell. Sci. 2019 ORF Clones MR205480
ATAD2 ATAD2 expression increases [18F]Fluorodeoxyglucose uptake value in lung adenocarcinoma via AKT-GLUT1/HK2 pathway BMB Rep 2019 ORF Clones RC218291
ATAD2 Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination Genes Dev. Jan 2015 ORF Clones RG218291
ATAT1 Ac-SDKP increases α-TAT 1 and promotes the apoptosis in lung fibroblasts and epithelial cells double-stimulated with TGF-β1 and silica Toxicol. Appl. Pharmacol. 2019 ORF Clones RC208373
ATAT1 ATAT1 is essential for regulation of homeostasis-retaining cellular responses in corticotrophs along hypothalamic-pituitary-adrenal axis Cell Tissue Res. 2017 ORF Clones RG208373
ATAT1 Intracellular localization of a-tubulin acetyltransferase ATAT1 in rat ciliated cells Med Mol Morphol Dec 2015 ORF Clones RC229162
Atf3 Activated transcription factor-3 in association with histone deacetylase-6 negatively regulates miR-199a2 transcription by chromatin remodeling and reduces endothelin-1 expression Mol. Cell. Biol. 2016 ORF Clones MR201634
ATF4 A novel autoregulatory loop between the Gcn2-Atf4 pathway and L-Proroline metabolism controls stem cell identity Cell Death Differ. Apr 2015 ORF Clones MR205957
ATF4 CCAAT/enhancer-binding protein ß promotes receptor activator of nuclear factor-kappa-B ligand (RANKL) expression and osteoclast formation in the synovium in rheumatoid arthritis Arthritis Research & Therapy Feb 2015 ORF Clones RG222709
ATG12 microRNA-146a relieves smoking relative chronic obstructive pulmonary disease through targeting ATG12 Int J Clin Exp Med 2019 ORF Clones RC202012
ATG12 Mir505-3p regulates axonal development via inhibiting the autophagy pathway by targeting Atg12 Autophagy 2017 ORF Clones MG200886
ATG4B Rab7b modulates autophagic flux by interacting with Atg4B EMBO Rep. 2017 ORF Clones RC200289
ATG5 RACK1 is an Interaction Partner of ATG5 and a Novel Regulator of Autophagy J. Biol. Chem. Jun 2016 ORF Clones RC235557
ATG7 APF lncRNA regulates autophagy and myocardial infarction by targeting miR-188-3p Nat Commun Apr 2015 ORF Clones MR210108
ATG9A Molecular determinants that mediate the sorting of human ATG9A from the endoplasmic reticulum Biochim. Biophys. Acta Jun 2016 ORF Clones RC222513
ATG9A ATG9A loss confers resistance to trastuzumab via c-Cbl mediated Her2 degradation Oncotarget 2016 ORF Clones RC222568
ATG9A SLC33A1/AT-1 Protein Regulates the Induction of Autophagy Downstream of IRE1/XBP1 Pathway J. Biol. Chem., Aug 2012; 287: 29921 - 29930. ORF Clones RC222513
ATOH1 Molecular cloning and functional characterization of chicken Atonal homologue 1: a comparison with human Atoh1 Biol. Cell Nov 2014 ORF Clones RC210192
ATOH1 Transcription Factors with Conserved Binding Sites Near ATOH1 on the POU4F3 Gene Enhance the Induction of Cochlear Hair Cells Mol. Neurobiol. July 2014 ORF Clones RG210192
ATOH8 Hepcidin suppression in β-thalassemia is associated with the down-regulation of atonal homolog 8 Int. J. Hematol. 2017 ORF Clones RC203005
ATOH8 The transcription factor ATOH8 is regulated by erythropoietic activity and regulates HAMP transcription and cellular pSMAD1,5,8 levels Br. J. Haematol. Nov 2013 ORF Clones RC203005
ATP11C ATP11C T418N, a gene mutation causing congenital hemolytic anemia, reduces flippase activity due to improper membrane trafficking Biochem. Biophys. Res. Commun. 2019 ORF Clones RC222893
ATP13A2 Mutant Atp13a2 proteins involved in parkinsonism are degraded by ER-associated degradation and sensitize cells to ER-stress induced cell death Hum. Mol. Genet., Sep 2011; 20: 3565 - 3577. ORF Clones RC227980
ATP1A1 GPR35 promotes glycolysis, proliferation, and oncogenic signaling by engaging with the sodium potassium pump Sci Signal 2019 ORF Clones RC201009
ATP1A1 Identification of Tumor Antigen AF20 as Glycosylated Transferrin Receptor 1 in Complex with Heat Shock Protein 90 and/or Transporting ATPase PloS one 2016 ORF Clones RC201009
ATP1A1 A Role for Na+,K+-ATPase a1 in Regulating Rab27a Localisation on Melanosomes PLoS ONE July 2014 ORF Clones RG201009
ATP1A2 Altered function of the glutamate aspartate transporter GLAST in glioblastoma bioRxiv 2018 ORF Clones RC208606
ATP1A3 GPR35 promotes glycolysis, proliferation, and oncogenic signaling by engaging with the sodium potassium pump Sci Signal 2019 ORF Clones RC203198
ATP1B2 Altered function of the glutamate aspartate transporter GLAST in glioblastoma bioRxiv 2018 ORF Clones RC220004
ATP2A2 Parkinson's disease-associated LRRK2-G2019S mutant acts through regulation of SERCA activity to control ER stress in astrocytes Acta Neuropathol Commun 2019 ORF Clones MR211518
ATP2B2 Neuroplastin and Basigin Are Essential Auxiliary Subunits of Plasma Membrane Ca(2+)-ATPases and Key Regulators of Ca(2+) Clearance Neuron 2017 ORF Clones MG223661
ATP5A1 The mitochondrial complex V-associated large-conductance inner membrane current is regulated by cyclosporine and dexpramipexole Mol. Pharmacol. Oct 2014 ORF Clones RC214840
ATP5B Parkinson's disease protein DJ-1 regulates ATP synthase protein components to increase neuronal process outgrowth Cell Death Dis 2019 ORF Clones RC201638
ATP5B The mitochondrial complex V-associated large-conductance inner membrane current is regulated by cyclosporine and dexpramipexole Mol. Pharmacol. Oct 2014 ORF Clones RC201638
ATP5C1 The mitochondrial complex V-associated large-conductance inner membrane current is regulated by cyclosporine and dexpramipexole Mol. Pharmacol. Oct 2014 ORF Clones RC201687
ATP5D The mitochondrial complex V-associated large-conductance inner membrane current is regulated by cyclosporine and dexpramipexole Mol. Pharmacol. Oct 2014 ORF Clones RC211715
ATP5E The mitochondrial complex V-associated large-conductance inner membrane current is regulated by cyclosporine and dexpramipexole Mol. Pharmacol. Oct 2014 ORF Clones RC210456
ATP5F1 The mitochondrial complex V-associated large-conductance inner membrane current is regulated by cyclosporine and dexpramipexole Mol. Pharmacol. Oct 2014 ORF Clones RC205088
ATP5G1 The mitochondrial permeability transition pore is a dispensable element for mitochondrial calcium efflux Cell Calcium. April 2014 ORF Clones RC200292
ATP5H The mitochondrial complex V-associated large-conductance inner membrane current is regulated by cyclosporine and dexpramipexole Mol. Pharmacol. Oct 2014 ORF Clones RC207908
ATP5MC1 TMEM70 facilitates biogenesis of mammalian ATP synthase by promoting subunit c incorporation into the rotor structure of the enzyme FASEB J. 2019 ORF Clones RC200292
ATP5O The mitochondrial complex V-associated large-conductance inner membrane current is regulated by cyclosporine and dexpramipexole Mol. Pharmacol. Oct 2014 ORF Clones RC204991
ATP5PD Mitochondrial reprogramming via ATP5H loss promotes multimodal cancer therapy resistance J. Clin. Invest. 2018 ORF Clones RC207908
ATP6AP1 Loss of TMEM106B Ameliorates Lysosomal and Frontotemporal Dementia-Related Phenotypes in Progranulin-Deficient Mice Neuron 2017 ORF Clones RC200394
ATP6V0C Loss of TMEM106B Ameliorates Lysosomal and Frontotemporal Dementia-Related Phenotypes in Progranulin-Deficient Mice Neuron 2017 ORF Clones RC203652
ATP6V0D1 Loss of TMEM106B Ameliorates Lysosomal and Frontotemporal Dementia-Related Phenotypes in Progranulin-Deficient Mice Neuron 2017 ORF Clones RC203498
ATP6V1A Specific autoantigens identified by sera obtained from mice that are immunized with testicular germ cells alone Sci Rep 2016 ORF Clones MR209449
ATR Colonic Lysine Homocysteinylation Induced by High-Fat Diet Suppresses DNA Damage Repair Cell Rep 2018 ORF Clones RC224837
ATRIP Colonic Lysine Homocysteinylation Induced by High-Fat Diet Suppresses DNA Damage Repair Cell Rep 2018 ORF Clones RC223562
ATRIP Identification of a BRCA1-mRNA Splicing Complex Required for Efficient DNA Repair and Maintenance of Genomic Stability Mol. Cell. April 2014 ORF Clones RC223562
ATXN1 Laminin signals initiate the reciprocal loop that informs breast-specific gene expression and homeostasis by activating NO, p53 and microRNAs Elife 2018 ORF Clones RC222862
AU022751 EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells Nat Commun 2019 ORF Clones MG214772
AU022751 GPIF constrains Polycomb Repressive Complex 2 activity in germ cells bioRxiv 2019 ORF Clones MG214772
AURKA MiR-26a-5p Inhibits Cell Proliferation and Enhances Doxorubicin Sensitivity in HCC Cells via Targeting AURKA Technol. Cancer Res. Treat. 2019 ORF Clones RC212018
AURKA Opposing roles for JNK and Aurora A in regulating WD40-Repeat Protein 62 association with spindle microtubules J. Cell. Sci. Dec 2014 ORF Clones RC212018
AUTS2 Deregulation of polycomb repressor complex 1 modifier AUTS2 in T-cell leukemia Oncotarget 2016 ORF Clones RC218943
AVP Viral rescue of magnocellular vasopressin cells in adolescent Brattleboro rats ameliorates diabetes insipidus, but not the hypoaroused phenotype Sci Rep 2019 ORF Clones RR211162
AVPR1A Subtle modifications to oxytocin produce ligands that retain potency and improved selectivity across species Sci Signal 2017 ORF Clones RC210436
AVPR1B Subtle modifications to oxytocin produce ligands that retain potency and improved selectivity across species Sci Signal 2017 ORF Clones RG215919
Awat2 Allosteric modulation of the substrate specificity of acyl-CoA wax alcohol acyltransferase 2 (AWAT2) J. Lipid Res 2017 ORF Clones MR219385
AXIN2 Functional analysis of a novel missense mutation in AXIN2 associated with non-syndromic tooth agenesis Eur. J. Oral Sci. Apr 2016 ORF Clones RC210931
AXIN2 Nuclear AXIN2 represses MYC gene expression Biochem. Biophys. Res. Commun. Dec 2013. ORF Clones RC210931
AXL ATP-binding cassette member B5 (ABCB5) promotes tumor cell invasiveness in human colorectal cancer J. Biol. Chem. 2018 ORF Clones RC206431
AXL Hepatitis C Virus Driven AXL Expression Suppresses the Hepatic Type I Interferon Response PLoS ONE Aug 2015 ORF Clones RC206431
AXL The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells Nature, Feb 2014. ORF Clones RC206431
AXL An Epithelial–Mesenchymal Transition Gene Signature Predicts Resistance to EGFR and PI3K Inhibitors and Identifies Axl as a Therapeutic Target for Overcoming EGFR Inhibitor Resistance Clin. Cancer Res., Jan 2013; 19: 279 - 290. ORF Clones RC206431
AZGP1 Abnormal Junctions and Permeability of Myelin in PMP22 Deficient Nerves Ann. Neurol. Dec 2013. ORF Clones RC207625
AZGP1 Glycosylation of closely spaced acceptor sites in human glycoproteins J Cell Sci. 2013 Oct 8 ORF Clones RC207625
B2M Development of a label-free FcRn-mediated transcytosis assay for in vitro characterization of FcRn interactions with therapeutic antibodies and Fc-fusion proteins J. Immunol. Methods 2018 ORF Clones RC207587
B2M Evidence of activation of the Nrf2 pathway in multiple sclerosis patients treated with delayed-release dimethyl fumarate in the Phase 3 DEFINE and CONFIRM studies Mult. Scler 2017 ORF Clones RC207587
B2M Key Residues at Third CDR3ß Position Impact Structure and Antigen Recognition of Human Invariant NK TCRs J. Immunol 2016 ORF Clones RC207587
B3GALT6 The spatial separation of processing and transport functions to the interior and periphery of the Golgi stack Elife 2018 ORF Clones MR204731
B3GALT6 A B3GALT6 variant in patient originally described as Al-Gazali syndrome and implicating the ER quality control in the mechanism of some β3GalT6-pathy mutations Clin. Genet. 2018 ORF Clones RC223942
B4GalT1 Proteomic analysis of the Simkania-containing vacuole: The central role of retrograde transport Mol. Microbiol. Sep 2015 ORF Clones RC100121
B4GALT7 Expansion of B4GALT7 linkeropathy phenotype to include perinatal lethal skeletal dysplasia Eur. J. Hum. Genet. 2019 ORF Clones RC200258
B4GALT7 The spatial separation of processing and transport functions to the interior and periphery of the Golgi stack Elife 2018 ORF Clones RC200258
BACE1 MicroRNA-200a-3p Mediates Neuroprotection in Alzheimer-Related Deficits and Attenuates Amyloid-Beta Overproduction and Tau Hyperphosphorylation via Coregulating BACE1 and PRKACB Front Pharmacol 2019 ORF Clones RC219054
BACE1 Direct imaging of APP proteolysis in living cells PeerJ Preprints 2017 ORF Clones RC209115
BACE1 Chemoproteomic profiling reveals that cathepsin D off-target activity drives ocular toxicity of ß-secretase inhibitors Nat Commun 2016 ORF Clones RC209115
BACE1 Presumed LRP1-targeting transport peptide delivers ß-secretase inhibitor to neurons in vitro with limited efficiency Sci Rep 2016 ORF Clones RG209115
BACE2 Design and Synthesis of Clinical Candidate PF-06751979: A Potent, Brain Penetrant, β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitor Lacking Hypopigmentation J. Med. Chem. 2018 ORF Clones RC204860
BACH1 Identification of a BRCA1-mRNA Splicing Complex Required for Efficient DNA Repair and Maintenance of Genomic Stability Mol. Cell. April 2014 ORF Clones RC224085
BACH2 microRNA-142 is upregulated by tumor necrosis factor-alpha and triggers apoptosis in human gingival epithelial cells by repressing BACH2 expression Am J Transl Res 2017 ORF Clones RC214061
BAG1 Mass spectrometry analyses of normal and polyglutamine expanded ataxin-3 reveal novel interaction partners involved in mitochondrial function Neurochemistry International 2017 ORF Clones RC201272
BAG3 BAG3-dependent expression of Mcl-1 confers resistance of mutant KRAS colon cancer cells to the HSP90 inhibitor AUY922 Mol. Carcinog.2017 ORF Clones RG202860
BAG6 Chaperone BAG6 is dispensable for MHC class I antigen processing and presentation Mol. Immunol. Nov 2015 ORF Clones RC201122
BAK1 Using CETSA assay and a mathematical model to reveal dual Bcl-2/Mcl-1 inhibition and on-target mechanism for ABT-199 and S1 Eur J Pharm Sci 2019 ORF Clones RC201216
BAMBI Downregulation of the TGFß Pseudoreceptor BAMBI in Non-Small Cell Lung Cancer Enhances TGFß Signaling and Invasion. Cancer Res. 2016 ORF Clones RG200195
BAMBI LPS/TLR4 Signaling Enhances TGF-ß Response Through Downregulating BAMBI During Prostatic Hyperplasia Sci Rep Jun 2016 ORF Clones RC200195
BAMBI Downregulation of the TGF-ß pseudoreceptor BAMBI in non-small cell lung cancer enhances TGF-ß signaling and invasion Cancer Res. May 2016 ORF Clones RG200195
BANF Dephosphorylation of barrier-to-autointegration-factor by protein phosphatase 4 and its role in cell mitosis J. Biol. Chem. Nov 2013 ORF Clones RG203270
BANK1 The BANK1 SLE-risk variants are associated with alterations in peripheral B cell signaling and development in humans Clin. Immunol. 2016 ORF Clones RC206985
BAP1 EZH2 Expression is increased in BAP1-mutant renal clear cell carcinoma and is related to poor prognosis J. Cancer 2018 ORF Clones RC200378
BARHL2 BARHL2 Methylation Using Gastric Wash DNA or Gastric Juice Exosomal DNA is a Useful Marker For Early Detection of Gastric Cancer in an H. pylori-Independent Manner. Clin Transl Gastroenterol 2016 ORF Clones RC217326
BARX1 The Polycomb-Dependent Epigenome Controls β Cell Dysfunction, Dedifferentiation, and Diabetes Cell Metab. 2018 ORF Clones MR222169
BATF Inflammation-induced Id2 promotes plasticity in regulatory T cells Nat Commun 2018 ORF Clones MR222114
BATF IRF4 haploinsufficiency in a family with Whipple's disease Elife 2018 ORF Clones RC207104
BATF2 BATF2 activates DUSP2 gene expression and upregulates NF-κB activity via phospho-STAT3 dephosphorylation Int. Immunol. 2018 ORF Clones MR203728
BATF2 Antitumor effect of Batf2 through IL-12 p40 up-regulation in tumor-associated macrophages Proc. Natl. Acad. Sci. U.S.A. 2017 ORF Clones MR203728
BAX Secreted frizzled-related protein 5 protects against oxidative stress-induced apoptosis in human aortic endothelial cells via downregulation of Bax J. Biochem. Mol. Toxicol. 2017 ORF Clones RC204369
BAZ1B Loss of WSTF results in spontaneous fluctuations of heterochromatin formation and resolution, combined with substantial changes to gene expression BMC Genomics. 2013 Oct 29;14(1):740 ORF Clones RC216159
BBC3 α7 nicotinic acetylcholine receptor upregulation by anti-apoptotic Bcl-2 proteins Nat Commun 2019 ORF Clones RC213203
BC017643 Eros is a novel transmembrane protein that controls the phagocyte respiratory burst and is essential for innate immunity J. Exp. Med 2017 ORF Clones MG201751
BCAR1 Activation of oncogenic tyrosine kinase signaling promotes insulin receptor-mediated cone photoreceptor survival Oncotarget 2016 ORF Clones MR231304
Bcl-2 Survivin inhibitor YM155 induces mitochondrial dysfunction, autophagy, DNA damage and apoptosis in BclxL silenced glioma cell lines Molecular carcinogenesis 2016 ORF Clones RC204498
BCL10 Impaired RASGRF1/ERK-mediated GM-CSF response characterizes CARD9 deficiency in French-Canadians J. Allergy Clin. Immunol. Oct 2015 ORF Clones RC208752
BCL2 Extra-mitochondrial prosurvival BCL-2 proteins regulate gene transcription by inhibiting the SUFU tumour suppressor Nat. Cell Biol. 2017 ORF Clones RC204498
BCL2 microRNA-143 acts as a suppressor of hemangioma growth by targeting Bcl-2 Gene 2017 ORF Clones RC204498
BCL2 Lemur tyrosine kinase 2 (LMTK2) is a determinant of cell sensitivity to apoptosis by regulating the levels of the BCL2 family members. Cancer Lett 2016 ORF Clones RC204498
BCL2 The RNA-binding protein LARP1 is a post-transcriptional regulator of survival and tumorigenesis in ovarian cancer Nucleic Acids Res. Dec 2015 ORF Clones RC204498
BCL2 Waltonitone induces apoptosis through mir-663-induced Bcl-2 downregulation in non-small cell lung cancer Tumour Biol. Oct 2014 ORF Clones RC204498
BCL2A1 Intrinsic Resistance to 5-Fluorouracil in a Brain Metastatic Variant of Human Breast Cancer Cell Line, MDA-MB-231BR PLoS ONE 2016 ORF Clones RC201965
BCL2L1 Novel tumor suppressor role of miRNA-876 in cholangiocarcinoma Oncogenesis 2019 ORF Clones RC201314
BCL2L1 Distinct modes of cell competition shape mammalian tissue morphogenesis Nature 2019 ORF Clones RC201314
BCL2L1 Extra-mitochondrial prosurvival BCL-2 proteins regulate gene transcription by inhibiting the SUFU tumour suppressor Nat. Cell Biol. 2017 ORF Clones RC201314
BCL2L1 Lemur tyrosine kinase 2 (LMTK2) is a determinant of cell sensitivity to apoptosis by regulating the levels of the BCL2 family members. Cancer Lett 2016 ORF Clones RC201314
BCL2L10 PNAS Plus: Ubiquitination, localization, and stability of an anti-apoptotic BCL2-like protein, BCL2L10/BCLb, are regulated by Ubiquilin1 PNAS, Jan 2012; 109: E119 - E126. ORF Clones RC211604
BCL2L11 Antitumor activity of S116836, a novel tyrosine kinase inhibitor, against imatinib-resistant FIP1L1-PDGFRa-expressing cells Oncotarget Jun 2014 ORF Clones RC207559
BCL2L11 Role for the Proapoptotic Factor BIM in Mediating Imatinib-induced Apoptosis in a c-KIT-dependent Gastrointestinal Stromal Tumor Cell Line J. Biol. Chem., May 2010; 285: 14109 - 14114 ORF Clones RC207559
BCL2L2 Extra-mitochondrial prosurvival BCL-2 proteins regulate gene transcription by inhibiting the SUFU tumour suppressor Nat. Cell Biol. 2017 ORF Clones RC211152
BCL3 Bcl3: a regulator of NF-κB inducible by TWEAK in acute kidney injury with anti-inflammatory and antiapoptotic properties in tubular cells Exp. Mol. Med. 2017 ORF Clones RC209116
BCL6 Integrated Systems Biology Approach Identifies Novel Maternal and Placental Pathways of Preeclampsia Front Immunol 2018 ORF Clones RG226102
BCL9 Genomic Profiling of Adult and Pediatric B-cell Acute Lymphoblastic Leukemia EBioMedicine 2016 ORF Clones RC219304
BCMA An anti-BCMA RNA aptamer for miRNA intracellular delivery Molecular Therapy - Nucleic Acids 2019 ORF Clones RC208851
Bcr Huntingtin-associated protein 1 interacts with breakpoint cluster region protein to regulate neuronal differentiation PLoS ONE Feb 2015 ORF Clones MR222863
BDH2 Downregulation of BDH2 modulates iron homeostasis and promotes DNA demethylation in CD4+ T cells of systemic lupus erythematosus. Clin. Immunol.2017 ORF Clones RC210586
BDLF3.5 The Epstein-Barr Virus Immunoevasins BCRF1 and BPLF1 Are Expressed by a Mechanism Independent of the Canonical Late Pre-initiation Complex PLoS Pathog. 2016 ORF Clones VC101185
BDLF4 The Epstein-Barr Virus Immunoevasins BCRF1 and BPLF1 Are Expressed by a Mechanism Independent of the Canonical Late Pre-initiation Complex PLoS Pathog. 2016 ORF Clones VC101065
BDNF N-Glycosylation is required for secretion of the precursor to brain-derived neurotrophic factor (proBDNF) carrying sulfated LacdiNAc structures J. Biol. Chem. 2019 ORF Clones RC212882
BDNF Sustained adrenergic signaling promotes intratumoral innervation through BDNF induction Cancer Res. 2018 ORF Clones RC217190
BDNF Noninvasive, targeted gene therapy for acute spinal cord injury using LIFU-mediated BDNF-loaded cationic nanobubble destruction Biochem. Biophys. Res. Commun. 2018 ORF Clones RR210837
BDNF MicroRNA‑744 inhibits tumor cell proliferation and invasion of gastric cancer via targeting brain‑derived neurotrophic factor Mol Med Rep 2017 ORF Clones RC217190
BDNF In vitro bioassay model for screening non-viral neurotrophic factor gene delivery systems for glaucoma treatment Drug Deliv Transl Res 2016 ORF Clones RC217190
BEND5 Hypermethylation of BEND5 contributes to cell proliferation and is a prognostic marker of colorectal cancer Oncotarget 2017 ORF Clones RG203968
BGLAP An isozyme-specific redox switch in human brain glycogen phosphorylase modulates its allosteric activation by AMP J. Biol. Chem. 2016 ORF Clones RC221096
BGLF3 The Epstein-Barr Virus Immunoevasins BCRF1 and BPLF1 Are Expressed by a Mechanism Independent of the Canonical Late Pre-initiation Complex PLoS Pathog. 2016 ORF Clones VC101064
BHLHA9 Mutations Affecting the BHLHA9 DNA-Binding Domain Cause MSSD, Mesoaxial Synostotic Syndactyly with Phalangeal Reduction, Malik-Percin Type American Journal of Human Genetics Nov 2014 ORF Clones RC228166
BIN1 BIN1 favors the spreading of Tau via extracellular vesicles Sci Rep 2019 ORF Clones MR207643
BIN1 Phosphodiesterase 5 inhibition improves contractile function and restores transverse tubule loss and catecholamine responsiveness in heart failure Sci Rep 2019 ORF Clones RC220616
BIN1 PDE5 inhibition improves symptom-free survival and restores transverse tubule loss and catecholamine responsiveness in heart failure bioRxiv 2018 ORF Clones RC220616
BIRC5 Dominant-negative ATF5 rapidly depletes survivin in tumor cells Cell Death Dis 2019 ORF Clones RC205935
BIRC5 Cloning, expression, and purification of the recombinant pro-apoptotic dominant-negative survivin T34A-C84A protein in Escherichia coli Protein Expr. Purif. 2019 ORF Clones RG205935
BIRC5 YM155 sensitizes non-small cell lung cancer cells to EGFR-tyrosine kinase inhibitors through the mechanism of autophagy induction Biochim Biophys Acta Mol Basis Dis 2018 ORF Clones RC205935
BIRC5 Survivin Monoclonal Antibodies Detect Survivin Cell Surface Expression and Inhibit Tumor Growth in vivo Clin. Cancer Res. 2018 ORF Clones RC205935
BIRC5 YM155 exerts potent cytotoxic activity against quiescent (G0/G1) multiple myeloma and bortezomib resistant cells via inhibition of survivin and Mcl-1 Oncotarget 2017 ORF Clones RG205935
BIRC5 Delivery of a survivin promoter-driven antisense survivin-expressing plasmid DNA as a cancer therapeutic: a proof-of-concept study Onco Targets Ther May 2016 ORF Clones RG205935
BIRC5 Polysaccharide from Lentinus edodes combined with oxaliplatin possesses the synergy and attenuation effect in hepatocellular carcinoma Cancer Lett. Apr 2016 ORF Clones RC205935
BIRC5 INVESTIGATIONS OF YM155, AN INHIBITOR OF SURVIVIN, AS A MOLECULAR MULTI-TARGETED AGENT FOR RENAL CELL CARCINOMA Thesis Jan 2016 ORF Clones RG205935
BIRC5 AMPK/mTOR-Mediated Inhibition of Survivin Partly Contributes to Metformin-Induced Apoptosis in Human Gastric Cancer Cell Cancer Biol. Ther. Dec 2014 ORF Clones RC205935
BIRC5 Survivin depletion inhibits tumor growth and enhances chemosensitivity in hepatocellular carcinoma Molecular MedicineReports July 2014 ORF Clones RG215858
BIRC5 ERK and AKT signaling cooperate to translationally regulate survivin expression for metastatic progression of colorectal cancer Oncogene doi:10.1038/onc.2013.122 ORF Clones RC205935
BIRC7 Livin/BIRC7 expression as malignancy marker in adrenocortical tumors Oncotarget 2016 ORF Clones RC204906
BMI1 Regulation of the Potential Marker for Intestinal Cells, Bmi1, by ß-Catenin and the Zinc Finger Protein KLF4: IMPLICATIONS FOR COLON CANCER J. Biol. Chem., Feb 2012; 287: 3760 - 3768. ORF Clones RC202871
BMP1 Cross-talk between miR-29 and Transforming Growth Factor-Betas in Trabecular Meshwork Cells Invest. Ophthalmol. Vis. Sci., Jun 2011; 52: 3567 - 3572 ORF Clones RC212538
BMP10 Furin Is the Major Processing Enzyme of the Cardiac-specific Growth Factor Bone Morphogenetic Protein 10 J. Biol. Chem., Jul 2011; 286: 22785 - 22794. ORF Clones RC215695
BMP2 Novel Synthesized Nanofibrous Scaffold Efficiently Delivered hBMP-2 Encoded in Adenoviral Vector to Promote Bone Regeneration Journal of Biomedical Nanotechnology 2017 ORF Clones RC214586
BMP2 Delivery of rhBMP-2 Plasmid DNA Complexes via a PLLA/Collagen Electrospun Scaffold Induces Ectopic Bone Formation Journal of Biomedical Nanotechnology Jun 2016 ORF Clones RC214586
BMP2 Bioreducible Cationic Poly (amido amine) s for Enhanced Gene Delivery and Osteogenic Differentiation of Tonsil-Derived Mesenchymal Stem Cells Journal of Biomedical Nanotechnology Mar 2016 ORF Clones RC214586
BMP2 Nanoplex-Mediated Codelivery of Fibroblast Growth Factor and Bone Morphogenetic Protein Genes Promotes Osteogenesis in Human Adipocyte-Derived Mesenchymal Stem Cells Mol. Pharm. Aug 2015 ORF Clones RC214586
BMP2 Inactivation of bone morphogenetic protein 2 may predict clinical outcome and poor overall survival for renal cell carcinoma through epigenetic pathways Oncotarget Apr 2015 ORF Clones RC214586
BMP2K Multivariate proteomic profiling identifies novel accessory proteins of coated vesicles J. Cell Biol., Apr 2012; 197: 141 - 160. ORF Clones RC215795
BMP4 Use of PTC124 for nonsense suppression therapy targeting BMP4 nonsense variants in vitro and the bmp4st72 allele in zebrafish PLoS ONE 2019 ORF Clones RC204473
BMP6 Heterozygous Mutations in BMP6 Pro-peptide Lead to Inappropriate Hepcidin Synthesis and Moderate Iron Overload in Humans Gastroenterology Nov 2015 ORF Clones RC212307
BMP7 Up-regulation of Bone Morphogenetic Protein 7 by 2-Hydroxycinnamaldehyde Attenuates HNSCC Cell Invasion Anticancer Res. 2018 ORF Clones RC203813
BMP7 Calcium oxalate crystals and oxalate induce an epithelial-to-mesenchymal transition in the proximal tubular epithelial cells: Contribution to oxalate kidney injury. Sci Rep 2017 ORF Clones RG203813
BMPR1A Heparan sulfate antagonism alters bone morphogenetic protein signaling and receptor dynamics, suggesting a mechanism in Hereditary Multiple Exostoses J. Biol. Chem. 2018 ORF Clones MR227586
BMPR2 CLIC4/Arf6 Pathway-A New Lead in BMPRII Inhibition in Pulmonary Hypertension Circulation Research 2018 ORF Clones RG208673
BMPR2 Heparan sulfate antagonism alters bone morphogenetic protein signaling and receptor dynamics, suggesting a mechanism in Hereditary Multiple Exostoses J. Biol. Chem. 2018 ORF Clones MR226598
BMX Hypoxia-induced upregulation of BMX kinase mediates therapeutic resistance in acute myeloid leukemia J. Clin. Invest. 2017 ORF Clones RC202002
BNIP3L Nix restores mitophagy and mitochondrial function to protect against PINK1/Parkin-related Parkinson's disease Sci Rep 2017 ORF Clones RC203315
BNIP3L Mitochondrial NIX Promotes Tumor Survival in the Hypoxic Niche of Glioblastoma Cancer Res. 2019 ORF Clones RC203315
BNIP3L FGF-2 Transcriptionally Down-Regulates the Expression of BNIP3L via PI3K/Akt/FoxO3a Signaling and Inhibits Necrosis and Mitochondrial Dysfunction Induced by High Concentrations of Hydrogen Peroxide in H9c2 Cells Cell. Physiol. Biochem 2016 ORF Clones RR215204
BOK Role of B-Cell Lymphoma 2 Ovarian Killer (BOK) in Acute Toxicity of Human Lung Epithelial Cells Caused by Cadmium Chloride Med. Sci. Monit. 2019 ORF Clones RC222963
BOLL Oncogenic Role of BOLL in Colorectal Cancer Dig. Dis. Sci. Jan 2015 ORF Clones RC223217
BP1 Electronegative low-density lipoprotein of patients with metabolic syndrome induces pathogenesis of aorta via disruption of STRA6 cascade J Diabetes Investig 2019 ORF Clones RG214515
BPTF BPTF transduces MITF-driven prosurvival signals in melanoma cells Proc. Natl. Acad. Sci. U.S.A. May 2016 ORF Clones RC217011
BRAF Acquired BRAF G469A Mutation as a Resistance Mechanism to First-Line Osimertinib Treatment in NSCLC Cell Lines Harboring an EGFR Exon 19 Deletion Target Oncol 2019 ORF Clones RC211013
BRAF A new GTF2I-BRAF fusion mediating MAPK pathway activation in pilocytic astrocytoma PLoS ONE 2017 ORF Clones RC211013
BRAF Common Oncogene Mutations and Novel SND1-BRAF Transcript Fusion in Lung Adenocarcinoma from Never Smokers Sci Rep May 2015 ORF Clones RG211013
Braf New BRAF knockin mice provide a pathogenetic mechanism of developmental defects and a therapeutic approach in cardio-facio-cutaneous syndrome Hum. Mol. Genet. July 2014 ORF Clones MR223023
BRAF Ring Finger Protein 149 Is an E3 Ubiquitin Ligase Active on Wild-type v-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF) J. Biol. Chem., Jul 2012; 287: 24017 - 24025. ORF Clones RC211013
BRCA1 USP9X stabilizes BRCA1 and confers resistance to DNA-damaging agents in human cancer cells Cancer Med 2019 ORF Clones RC219679
BRD7 Bromodomain protein 7 interacts with PRMT5 and PRC2, and is involved in transcriptional repression of their target genes Nucleic Acids Res., Jul 2011; 39: 5424 - 5438. ORF Clones RC208734
BRDT Whole-exome sequencing identified a homozygous BRDT mutation in a patient with acephalic spermatozoa Oncotarget 2017 ORF Clones RC222276
BRMS1 A pro-apoptotic function of iASPP by stabilizing p300 and CBP through inhibition of BRMS1 E3 ubiquitin ligase activity Cell Death Dis Feb 2015 ORF Clones RG203428
Brn3b Bcl-2, Bcl-xL, and p-AKT are involved in neuroprotective effects of transcription factor Brn3b in an ocular hypertension rat model of glaucoma. Mol. Vis. 2016 ORF Clones MR223071
BRS3 Novel chiral-diazepines function as specific, selective receptor agonists with variable coupling and species variability in human, mouse and rat BRS-3 receptor cells Peptides Oct 2015 ORF Clones MR221973
BRS3 Novel chiral-diazepines function as specific, selective receptor agonists with variable coupling and species variability in human, mouse and rat BRS-3 receptor cells Peptides Oct 2015 ORF Clones RN209450
BSG Membrane-anchored carbonic anhydrase IV interacts with monocarboxylate transporters via their chaperones CD147 and GP70 J. Biol. Chem. 2018 ORF Clones RC203894
BSG Neuroplastin and Basigin Are Essential Auxiliary Subunits of Plasma Membrane Ca(2+)-ATPases and Key Regulators of Ca(2+) Clearance Neuron 2017 ORF Clones MR225905
BSG Apolipoprotein D internalization is a basigin dependent mechanism J. Biol. Chem. Apr 2015 ORF Clones RC203894
BST2 Japanese encephalitis virus counteracts BST2 restriction via its envelope protein E. Virology 2017 ORF Clones RC207540
BST2 HSV-2 glycoprotein gD targets the CC domain of tetherin and promotes tetherin degradation via lysosomal pathway Virol. J. 2016 ORF Clones RC207540
BST2 Ebola Virus Glycoprotein Counteracts BST-2/Tetherin Restriction in a Sequence-Independent Manner That Does Not Require Tetherin Surface Removal J. Virol., Jul 2010; 84: 7243 - 7255. ORF Clones RC207540
BST2 Ebola glycoprotein counteracts BST-2/tetherin restriction in a sequence independent manner that does not require tetherin surface removal. J. Virol., May 2010; 10.1128/JVI.02636-09 ORF Clones RC207540
BTD Effect of BTD gene variants on in vitro biotinidase activity Mol. Genet. Metab. 2019 ORF Clones RC204153
BTG3 MicroRNA-519c-3p promotes tumor growth and metastasis of hepatocellular carcinoma by targeting BTG3 Biomed. Pharmacother. 2019 ORF Clones RC221056
BTG3 Control of PD-L1 expression by miR-140/142/340/383 and oncogenic activation of the OCT4-miR-18a pathway in cervical cancer Oncogene 2018 ORF Clones RC221056
BTK BTK modulates p73 activity to induce apoptosis independently of p53 Cell Death Discov 2018 ORF Clones RG211582
BTK WDR1 is a novel EYA3 substrate and its dephosphorylation induces modifications of the cellular actin cytoskeleton Sci Rep 2018 ORF Clones RC211582
BTK Dual SYK/JAK inhibition overcomes ibrutinib resistance in chronic lymphocytic leukemia: Cerdulatinib, but not ibrutinib, induces apoptosis of tumor cells protected by the microenvironment Oncotarget 2017 ORF Clones RC211582
BTK Identification of a structurally novel BTK mutation that drives ibrutinib resistance in CLL Oncotarget 2016 ORF Clones RC211582
BTK BTK Modulates p53 Activity to Enhance Apoptotic and Senescent Responses Cancer Res. 2016 ORF Clones RG211582
BTN3A1 Critical Roles for Coiled-Coil Dimers of Butyrophilin 3A1 in the Sensing of Prenyl Pyrophosphates by Human Vγ2Vδ2 T Cells J. Immunol. 2019 ORF Clones RC216344
Bub1b Lack of Diaph3 relaxes the spindle checkpoint causing the loss of neural progenitors Nat Commun 2016 ORF Clones MR211540
BVLF1 The Epstein-Barr Virus Immunoevasins BCRF1 and BPLF1 Are Expressed by a Mechanism Independent of the Canonical Late Pre-initiation Complex PLoS Pathog. 2016 ORF Clones VC101092
c-Jun Targeting EP4 downstream c-Jun through ERK1/2-mediated reduction of DNMT1 reveals novel mechanism of solamargine-inhibited growth of lung cancer cells J. Cell. Mol. Med. 2016 ORF Clones MG227043
c-myc Cip2a promotes cell cycle progression in triple-negative breast cancer cells by regulating the expression and nuclear export of p27Kip1 Oncogene 2016 ORF Clones SC112715
C10ORF90 A functional genetic variant in fragile-site gene FATS modulates the risk of breast cancer in triparous women BMC Cancer Jul 2015 ORF Clones RC223255
C19ORF12 Mutations of C19orf12, coding for a transmembrane glycine zipper containing mitochondrial protein, cause mis-localization of the protein, inability to respond to oxidative stress and increased mitochondrial Ca2+ Frontiers in Genetics May 2015 ORF Clones RG216851
C1QBP A novel small molecule inhibitor of p32 mitochondrial protein overexpressed in glioma J Transl Med 2017 ORF Clones RC201742
C1QC ASTN2 modulates synaptic strength by trafficking and degradation of surface proteins bioRxiv 2018 ORF Clones MR203092
C1QL3 Complement 1q like-3 protein inhibits insulin secretion from pancreatic β-cells via the cell adhesion G protein-coupled receptor BAI3 J. Biol. Chem. 2018 ORF Clones MR203279
C1QTNF4 De novo mutations implicate novel genes in systemic lupus erythematosus Hum. Mol. Genet. 2018 ORF Clones RC207458
C22orf32 EMRE Is a Matrix Ca(2+) Sensor that Governs Gatekeeping of the Mitochondrial Ca(2+) Uniporter Cell Rep Jan 2016 ORF Clones RC205947
C2ORF40 Open reading frame mining identifies a TLR4 binding domain in the primary sequence of ECRG4 Cell. Mol. Life Sci. 2019 ORF Clones SC104814
C4A Increased expression of schizophrenia-associated gene C4 leads to hypoconnectivity of prefrontal cortex and reduced social interaction bioRxiv 2019 ORF Clones RC235329
C5AR1 Primary squamous cell carcinoma of the extrahepatic bile duct: A case report Gastroenterol Hepatol 2019 ORF Clones MR225064
C5AR1 RP S19 C-terminal peptide trimer acts as a C5a receptor antagonist Biochemistry and Biophysics Reports May 2016 ORF Clones RG203784
C6 Differential contribution of C5aR and C5b-9 pathways to renal thrombic microangiopathy and macrovascular thrombosis in mice carrying an atypical hemolytic syndrome-related factor H mutation Kidney International 2019 ORF Clones MR210555
C6ORF106 C6orf106 accelerates pancreatic cancer cell invasion and proliferation via activating ERK signaling pathway Mol. Cell. Biochem. 2018 ORF Clones RC209929
C6ORF106 A novel biomarker C6orf106 promotes the malignant progression of breast cancer Tumour Biol. May 2015 ORF Clones RC209929
C6ORF106 C6orf106 enhances NSCLC cell invasion by upregulating vimentin, and downregulating E-cadherin and P120ctn Tumour Biol. Mar 2015 ORF Clones RC209929
C9 Differential contribution of C5aR and C5b-9 pathways to renal thrombic microangiopathy and macrovascular thrombosis in mice carrying an atypical hemolytic syndrome-related factor H mutation Kidney International 2019 ORF Clones MR208897
C9orf119 The Role of the Human SWI5-MEI5 Complex in Homologous Recombination Repair J. Biol. Chem., Mar 2011; 286: 9888 - 9893 ORF Clones RC211457
C9ORF72 C9orf72 Proteins Regulate Autophagy and Undergo Autophagosomal or Proteasomal Degradation in a Cell Type-Dependent Manner Cells 2019 ORF Clones RG209700
C9ORF72 Novel antibodies reveal presynaptic localization of C9orf72 protein and reduced protein levels in C9orf72 mutation carriers Acta Neuropathol Commun 2018 ORF Clones RC222418
C9ORF72 Novel antibodies reveal presynaptic localization of C9orf72 protein and reduced protein levels in C9orf72 mutation carriers Acta Neuropathol Commun 2018 ORF Clones RC209700
C9ORF72 Novel antibodies reveal presynaptic localization of C9orf72 protein and reduced protein levels in C9orf72 mutation carriers Acta Neuropathol Commun 2018 ORF Clones MR214022
C9ORF72 Novel antibodies reveal presynaptic localization of C9orf72 protein and reduced protein levels in C9orf72 mutation carriers Acta Neuropathol Commun 2018 ORF Clones MR204567
C9ORF72 Interrelationship between the Levels of C9orf72 and Amyloid-β Protein Precursor and Amyloid-β in Human Cells and Brain Samples J. Alzheimers Dis. 2018 ORF Clones RG222418
C9ORF72 Interrelationship between the Levels of C9orf72 and Amyloid-β Protein Precursor and Amyloid-β in Human Cells and Brain Samples J. Alzheimers Dis. 2018 ORF Clones RC209700
C9orf72 Increased expression of the frontotemporal dementia risk factor TMEM106B causes C9orf72-dependent alterations in lysosomes Hum. Mol. Genet. Apr 2016 ORF Clones RC209700
C9ORF72 C9ORF72 Regulates Stress Granule Formation and Its Deficiency Impairs Stress Granule Assembly, Hypersensitizing Cells to Stress Mol. Neurobiol. Apr 2016 ORF Clones RC222418
C9ORF72 C9ORF72 Regulates Stress Granule Formation and Its Deficiency Impairs Stress Granule Assembly, Hypersensitizing Cells to Stress Mol. Neurobiol. Apr 2016 ORF Clones RC209700
C9ORF72 C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking Hum. Mol. Genet., Feb 2014. ORF Clones RG209700
C9orf72 Targeting RNA Foci in iPSC-Derived Motor Neurons from ALS Patients with a C9ORF72 Repeat Expansion Sci Transl Med. 2013 Oct 23;5(208):208ra149 ORF Clones RC209700
C9orf72 Targeting RNA Foci in iPSC-Derived Motor Neurons from ALS Patients with a C9ORF72 Repeat Expansion Sci Transl Med. 2013 Oct 23;5(208):208ra149 ORF Clones RC222418
CA12 Governing effect of regulatory proteins for Cl(-)/HCO3(-) exchanger 2 activity Channels (Austin) Dec 2015 ORF Clones RC204810
CA8 Profound analgesia is associated with a truncated peptide resulting from tissue specific alternative splicing of DRG CA8-204 regulated by an exon-level cis-eQTL PLoS Genet. 2019 ORF Clones RC210228
CA8 Human carbonic anhydrase-8 AAV8 gene therapy inhibits nerve growth factor signaling producing prolonged analgesia and anti-hyperalgesia in mice Gene Ther. 2018 ORF Clones RC210228
CA9 Tumor antigen glycosaminoglycan modification regulates antibody-drug conjugate delivery and cytotoxicity Oncotarget 2017 ORF Clones RC204839
CACHD1 CACHD1 is an α2δ-like protein that modulates CaV3 voltage-gated calcium channel activity J. Neurosci. 2018 ORF Clones RC224006
CACNA1A Absence-like seizures and their pharmacological profile in tottering-6j mice Biochem. Biophys. Res. Commun. May 2015 ORF Clones MG227166
CACNA1G Mechanism of direct Cav2.2 channel block by the ?-opioid receptor agonist U50488H. Neuropharmacology May 2016 ORF Clones RG219695
CACNA1H Recurrent gain of function mutation in calcium channel CACNA1H causes early-onset hypertension with primary aldosteronism Elife Apr 2015 ORF Clones RC212772
CACNA1I A rare schizophrenia risk variant of CACNA1I disrupts CaV3.3 channel activity Sci Rep 2016 ORF Clones RC219179
CACNA1S Na leak with gating pore properties in hypokalemic periodic paralysis V876E mutant muscle Ca channel J. Gen. Physiol.2017 ORF Clones RG223574
CACNA2D1 Discovering the pharmacodynamics of conolidine and cannabidiol using a cultured neuronal network based workflow Sci Rep 2019 ORF Clones RC219081
CACNA2D2 Neomorphic effects of recurrent somatic mutations in Yin Yang 1 in insulin-producing adenomas Proc. Natl. Acad. Sci. U.S.A. Mar 2015 ORF Clones RC230662
CACNB2 CACNB2 is associated with aberrant RAS-MAPK signaling in hypertensive Dahl Salt-Sensitive rats Biochem. Biophys. Res. Commun. 2019 ORF Clones RC211669
CACNB4 Selective Loss of Smaller Spines in Schizophrenia Am J Psychiatry 2017 ORF Clones RR204310
Cactin Human Cactin interacts with DHX8 and SRRM2 to assure efficient pre-mRNA splicing and sister chromatid cohesion J. Cell. Sci 2017 ORF Clones RC221444
CALCR Copper transporter 1 in human colorectal cancer cell lines: Effects of endogenous and modified expression on oxaliplatin cytotoxicity Journal of Inorganic Biochemistry 2017 ORF Clones RC228419
CALCR Amylin Modulates the Mesolimbic Dopamine System toControl Energy Balance Neuropsychopharmacology Jul 2014 ORF Clones RN200228
CALHM1 Exosomes mediate the cell-to-cell transmission of IFN-a-induced antiviral activity Nature Immunology 14, 793-803 doi:10.1038/ni.2647 ORF Clones RC206902
CALR Calreticulin Ins5 and Del52 mutations impair unfolded protein and oxidative stress responses in K562 cells expressing CALR mutants Sci Rep 2019 ORF Clones RC203222
CALR Mechanistic Understanding of N-Glycosylation in Ebola Virus Glycoprotein Maturation and Function J. Biol. Chem 2017 ORF Clones RC203222
CALR Heterozygous NPR2 mutations cause disproportionate short stature, similar to Léri-Weill dyschondrosteosis J. Clin. Endocrinol. Metab. Jun 2015 ORF Clones RC203222
CALR Experimental validation of predicted subcellular localizations of human proteins BMC Res Notes Dec 2014 ORF Clones RC100108
CALR Rho GTPases RhoA and Rac1 Mediate Effects of Dietary Folate on Metastatic Potential of A549 Cancer Cells through the Control of Cofilin Phosphorylation J. Biol. Chem. Aug 2014 ORF Clones RC203222
CALR A Point Mutation in the Amino Terminus of TLR7 Abolishes Signaling without Affecting Ligand Binding J. Immunol., Apr 2011; 186: 4213 - 4222 ORF Clones RC203222
CALR (ETS) Mitochondrial protein import is regulated by p17/PERMIT to mediate lipid metabolism and cellular stress Sci Adv 2019 ORF Clones RC100108
CALU Calumenin contributes to ER-Ca(2+) homeostasis in bronchial epithelial cells expressing WT and F508del mutated CFTR and to F508del-CFTR retention Cell Calcium 2017 ORF Clones MR204503
CALU Quantitative proteomics reveals the roles of peroxisome-associated proteins in anti-viral innate immune responses Mol. Cell Proteomics Jun 2015 ORF Clones RC200589
CAMK2A Redox-sensitive calcium/calmodulin-dependent protein kinase IIα in angiotensin II intra-neuronal signaling and hypertension Redox Biology 2019 ORF Clones MR207662
Camk2a Phosphoproteomic Analysis Reveals a Novel Mechanism of CaMKIIa Regulation Inversely Induced by Cocaine Memory Extinction versus Reconsolidation J. Neurosci. 2016 ORF Clones RR201121
CAMK2A Methionine Mistranslation Bypasses the Restraint of the Genetic Code to Generate Mutant Proteins with Distinct Activities PLoS Genet. Dec 2015 ORF Clones RC218186
CAMK2A Mechanism of Hypoxia-Induced NF-{kappa}B Mol. Cell. Biol., Oct 2010; 30: 4901 - 4921 ORF Clones RC205202
CAMK2B Wip1 phosphatase modulates both long-term potentiation and long-term depression through the dephosphorylation of CaMKII Cell Adh Migr 2016 ORF Clones MR220945
CAMK2D Ischemic Injury-Induced CaMKIIδ and CaMKIIγ Confer Neuroprotection Through the NF-κB Signaling Pathway Mol. Neurobiol. 2018 ORF Clones MR207996
CAMK2D Induction of lumen formation in a 3D model of mammary morphogenesis by transcriptional regulator ID4: Role of CaMK2D in the epigenetic regulation of ID4 gene expression J. Biol. Chem. Jun 2016 ORF Clones RC207454
CAMKK2 Pharmacological stimulation of nuclear factor (erythroid-derived 2)-like 2 translation activates antioxidant responses J. Biol. Chem. 2017 ORF Clones MR208650
CAMKK2 Data for the co-expression and purification of human recombinant CaMKK2 in complex with calmodulin in Escherichia coli Data in Brief 2016 ORF Clones RG219809
CAMP Polyplexes system Vs Nucleofection for human skin cells transfection and effect of IRES sequence Tissue Eng Part C Methods 2018 ORF Clones RC208872
CAMSAP3 Determinants of Polar versus Nematic Organization in Networks of Dynamic Microtubules and Mitotic Motors Cell 2018 ORF Clones RC216127
CAPN1 Defective tubulin detyrosination causes structural brain abnormalities with cognitive deficiency in humans and mice Hum. Mol. Genet. 2019 ORF Clones MR222250
CAPN5 CAPN5 mutation in hereditary uveitis: the R243L mutation increases calpain catalytic activity and triggers intraocular inflammation in a mouse model Hum. Mol. Genet. May 2015 ORF Clones RG202045
CAPN5 CAPN5 gene silencing by short hairpin RNA interference BMC Res Notes Sep 2014 ORF Clones RC202045
CAPRIN1 Combining laser capture microdissection and proteomics reveals an active translation machinery controlling invadosome formation Nat Commun 2018 ORF Clones RC200300
CAPS1 CAPS1 Negatively Regulates Hepatocellular Carcinoma Development through Alteration of Exocytosis-Associated Tumor Microenvironment Int J Mol Sci 2016 ORF Clones RC210271
CAPSID HIV blocks Type I IFN signaling through disruption of STAT1 phosphorylation Innate Immun 2018 ORF Clones VC101725
CAPZA1 CAPZA1 determines the risk of gastric carcinogenesis by inhibiting Helicobacter pylori CagA-degraded autophagy Autophagy 2019 ORF Clones RC201642
CAR2 Restored immunosuppressive effect of mesenchymal stem cells on B cells after OAZ downregulation in patients with systemic lupus erythematosus Arthritis & rheumatology Sep 2014 ORF Clones RC201974
CARD14 Loss-of-function mutations in CARD14 are associated with a severe variant of atopic dermatitis J. Allergy Clin. Immunol. 2018 ORF Clones RC217455
CARD8 Loss-of-function CARD8 mutation causes NLRP3 inflammasome activation and Crohn's disease J. Clin. Invest. 2018 ORF Clones RC230245
CARD9 Impaired RASGRF1/ERK-mediated GM-CSF response characterizes CARD9 deficiency in French-Canadians J. Allergy Clin. Immunol. Oct 2015 ORF Clones RG215899
CASK The Kv1-associated molecules TAG-1 and Caspr2 are selectively targeted to axon initial segment in hippocampal neurons J. Cell. Sci. 2017 ORF Clones RC220531
CASP1 DPP8/9 inhibitors are universal activators of functional NLRP1 alleles Cell Death Dis 2019 ORF Clones RC218364
CASP1 DPP8/DPP9 inhibitor-induced pyroptosis for treatment of acute myeloid leukemia Nat. Med. 2018 ORF Clones RC218364
CASP1 Cutting Edge: Mitochondrial Assembly of the NLRP3 Inflammasome Complex Is Initiated at Priming J. Immunol. 2018 ORF Clones MR227666
CASP1 N-terminal degradation activates the Nlrp1b inflammasome bioRxiv 2018 ORF Clones MR227666
CASP1 Noncanonical Inflammasome Activation of Caspase-4/Caspase-11 Mediates Epithelial Defenses against Enteric Bacterial Pathogens Cell Host Microbe Aug 2014 ORF Clones RC218364
CASP1 A cellular genome-wide association study reveals human variation in microtubule stability and a role in inflammatory cell death Mol Biol Cell. 2013 Oct 30 ORF Clones RC218364
CASP10 Caspase-10 inhibits ATP-citrate lyase-mediated metabolic and epigenetic reprogramming to suppress tumorigenesis Nat Commun 2019 ORF Clones RC206379
CASP2 Structural and Enzymatic Insights into Caspase-2 Protein Substrate Recognition and Catalysis J. Biol. Chem., Sep 2011; 286: 34147 - 34154. ORF Clones RC200669
CASP3 Cutting Edge: Mitochondrial Assembly of the NLRP3 Inflammasome Complex Is Initiated at Priming J. Immunol. 2018 ORF Clones MR203736
CASP3 Gamma secretase Activating Protein is a Substrate for Caspase-3: Implications for Alzheimer's Disease Biological Psychiatry Jun 2014 ORF Clones RC204444
CASP6 Nitrite protects neurons against hypoxic damage through <i>S</i>-nitrosylation of caspase-6 Antioxid. Redox Signal. 2018 ORF Clones MR203708
CASP6 Palmitoylation of caspase-6 by HIP14 regulates its activation Cell Death Differ 2016 ORF Clones RC201349
CASP8 A proteasome-resistant fragment of NIK mediates oncogenic NF-κB signaling in schwannomas Hum. Mol. Genet. 2018 ORF Clones RC223744
CASP9 A Fragment-Derived Clinical Candidate for Antagonism of X-Linked and Cellular Inhibitor of Apoptosis Proteins: 1-(6-[(4-Fluorophenyl)methyl]-5-(hydroxymethyl)-3,3-dimethyl-1 H,2 H,3 H-pyrrolo[3,2- b]pyridin-1-yl)-2-[(2 R,5 R)-5-methyl-2-([(3R)-3-methylmorpholin-4-yl]methyl)piperazin-1-yl]ethan-1-one (ASTX660) J. Med. Chem. 2018 ORF Clones RC200635
CASP9 Genetic screening and functional analysis of CASP9 mutations in a Chinese cohort with neural tube defects CNS Neurosci Ther 2018 ORF Clones RC200635
CASPR2 The CASPR2 cell adhesion molecule functions as a tumor suppressor gene in glioma Oncogene (16 August 2010) doi:10.1038/onc.2010.342 Original Article ORF Clones RC210836
CASR Activation of the calcium sensing receptor attenuates TRPV6-dependent intestinal calcium absorption JCI Insight 2019 ORF Clones RC211229
CASR Activation of the Ca(2+)-sensing receptors increases currents through inward rectifier K(+) channels via activation of phosphatidylinositol 4-kinase Pflugers Arch. 2016 ORF Clones RG230646
CaSR Increase of Calcium Sensing Receptor Expression Is Related to Compensatory Insulin Secretion during Aging in Mice PLoS ONE 2016 ORF Clones MR223303
CASR The calcium-sensing receptor is silenced by genetic and epigenetic mechanisms in unfavorable neuroblastomas and its reactivation induces ERK1/2-dependent apoptosis Carcinogenesis, Feb 2013; 34: 268 - 276. ORF Clones RG211229
CASR Regulator of G Protein Signaling 5 Is Highly Expressed in Parathyroid Tumors and Inhibits Signaling by the Calcium-Sensing Receptor Mol. Endocrinol., May 2011; 25: 867 - 876 ORF Clones RC211229
Cass4 Overexpression of CASS4 promotes invasion in non-small cell lung cancer by activating the AKT signaling pathway and inhibiting E-cadherin expression Tumour Biol. 2016 ORF Clones RC228580
CAST Calpastatin phosphorylation regulates radiation-induced calpain activity in glioblastoma Oncotarget 2018 ORF Clones RC222278
CAST Calpains Are Downstream Effectors of bax-Dependent Excitotoxic Apoptosis J. Neurosci., Feb 2012; 32: 1847 - 1858. ORF Clones MR209946
CASZ1 Essential Role of the Zinc Finger Transcription Factor Casz1 for Mammalian Cardiac Morphogenesis and Development J. Biol. Chem. Sep 2014 ORF Clones RG208715
CAT Hexavalent chromium induces malignant transformation of human lung bronchial epithelial cells via ROS-dependent activation of miR-21-PDCD4 signaling Oncotarget 2016 ORF Clones RC210763
CAT L-Ascorbic acid can abrogate SVCT2-dependent cetuximab resistance mediated by mutant KRAS in human colon cancer cells Free Radic. Biol. Med. Mar 2016 ORF Clones RC210763
CAT Role of reactive oxygen species in arsenic-induced transformation of human lung bronchial epithelial (BEAS-2B) cells Biochem. Biophys. Res. Commun. Jan 2015 ORF Clones RC210763
CAT Luteolin inhibits Cr (VI)-induced malignant cell transformation of human lung epithelial cells by targeting ROS mediated multiple cell signaling pathways Toxicology and Applied Pharmacology Oct 2014 ORF Clones RC210763
CAT1 M2 polarization of macrophages facilitates arsenic-induced cell transformation of lung epithelial cells Oncotarget 2017 ORF Clones RC210763
CatD Chemoproteomic profiling reveals that cathepsin D off-target activity drives ocular toxicity of ß-secretase inhibitors Nat Commun 2016 ORF Clones RC200719
CAV1 SMPDL3b modulates insulin receptor signaling in diabetic kidney disease Nat Commun 2019 ORF Clones RC210274
CAV1 SMPDL3b modulates insulin receptor signaling in diabetic kidney disease Nat Commun 2019 ORF Clones RG210274
CAV1 Dipeptidyl peptidase-4 plays a pathogenic role in BSA-induced kidney injury in diabetic mice Sci Rep 2019 ORF Clones RC210274
CAV1 Caveolin-1-Autophagy Pathway Mediated Cardiomyocyte Hypertrophy Induced by Apelin-13 DNA Cell Biol. 2017 ORF Clones RR200414
CAV1 Cav-1 Upregulation Slows Migration Velocity in BLM Melanoma The FASEB Journal 2017 ORF Clones RC210274
CAV1 Real-time imaging of sodium glucose transporter (SGLT1) trafficking and activity in single cells Physiol Rep 2017 ORF Clones RC210274
CAV1 DNA methylation profiling identifies PTRF/Cavin-1 as a novel tumor suppressor in Ewing sarcoma when co-expressed with caveolin-1 Cancer Lett. 2016 ORF Clones RC210274
Cav1 Inflammatory cytokines induce caveolin-1/ß-catenin signalling in rat nucleus pulposus cell apoptosis through the p38 MAPK pathway Cell Prolif. Jun 2016 ORF Clones RR200414
CAV1 ROR1 sustains caveolae and survival signalling as a scaffold of cavin-1 and caveolin-1 Nat Commun 2016 ORF Clones RC210274
CAV1 Caveolin-1 is a negative regulator of NADPH oxidase-derived reactive oxygen species Free Radic. Biol. Med. May 2014 ORF Clones RC210274
CAV3 The STAT5-regulated miR-193b locus restrains mammary stem and progenitor cell activity and alveolar differentiation Dev. Biol. Sep 2014 ORF Clones MR226246
CAV3 Identification and functional analysis of a new putative caveolin-3 variant found in a patient with sudden unexplained death J. Biomed. Sci. Jun 2014 ORF Clones RC210118
CBFA2T2 Application of immobilized ATP to the study of NLRP inflammasomes Arch. Biochem. Biophys. 2019 ORF Clones RC202013
CBFB The RUNX transcriptional co-regulator, CBFβ, suppresses migration of ER+ breast cancer cells by repressing ERα-mediated expression of the migratory factor TFF1. Molecular Cancer Research 2019 ORF Clones RC211623
CBL IFT20 modulates ciliary PDGFRα signaling by regulating the stability of Cbl E3 ubiquitin ligases J. Cell Biol. 2017 ORF Clones RC214069
CBL CBL mutations in myeloproliferative neoplasms are also found in the gene’s proline-rich domain and in patients with the V617FJAK2 Haematologica, Aug 2012; 97: 1234 - 1241. ORF Clones RC214069
CBLB LncRNA DUXAP9-206 directly binds with Cbl-b to augment EGFR signaling and promotes non-small cell lung cancer progression J. Cell. Mol. Med. 2018 ORF Clones RC206047
CBLB CBL mutations in myeloproliferative neoplasms are also found in the gene’s proline-rich domain and in patients with the V617FJAK2 Haematologica, Aug 2012; 97: 1234 - 1241. ORF Clones RC206047
CBLN4 Cerebellin 4, a synaptic protein that enhances inhibitory activity and resistance of neurons to Amyloid beta toxicity Neurobiology of Aging Nov 2014 ORF Clones MR201963
CBR1 Carbonyl reductase 1 is a new target to improve the effect of radiotherapy on head and neck squamous cell carcinoma J. Exp. Clin. Cancer Res. 2018 ORF Clones RG204950
CBR1 Gene therapy for ovarian cancer using carbonyl reductase 1 DNA with a polyamidoamine dendrimer in mouse models Cancer Gene Ther. Nov 2015 ORF Clones RG204950
CBS A highly selective and sensitive near-infrared fluorescent probe for imaging of hydrogen sulphide in living cells and mice Sci Rep Jan 2016 ORF Clones RC201755
CBS Two-Photon Fluorescent Probe for Detection of Exogenous and Endogenous Hydrogen Persulfide and Polysulfide in Living Organisms Anal. Chem. Feb 2015 ORF Clones RC201755
CBWD3 Identification of the Human Zinc Transcriptional Regulatory Element (ZTRE): A PALINDROMIC PROTEIN-BINDING DNA SEQUENCE RESPONSIBLE FOR ZINC-INDUCED TRANSCRIPTIONAL REPRESSION J. Biol. Chem., Oct 2012; 287: 36567 - 36581. ORF Clones RC221698
CBX2 Assembling the jigsaw puzzle: CBX2 isoform 2 and its targets in disorders/differences of sex development Mol Genet Genomic Med 2018 ORF Clones RC216313
CBX2 CBX2 and the Ovary: Novel Insights into Regulatory Networks in Humans Journal of Gynecology & Reproductive Medicine 2018 ORF Clones RC216313
CBX6 CBX6 is negatively regulated by EZH2 and plays a potential tumor suppressor role in breast cancer Sci Rep 2019 ORF Clones RC204166
CBX6 Altered expression of polycomb group genes in glioblastoma multiforme PLoS ONE e80970 Nov 2013 ORF Clones RC204166
CBX7 Cbx7 is epigenetically silenced in glioblastoma and inhibits cell migration by targeting YAP/TAZ-dependent transcription Sci Rep Jun 2016 ORF Clones RC208424
CCBE1 A Multiplex Kindred with Hennekam Syndrome due to Homozygosity for a CCBE1 Mutation that does not Prevent Protein Expression J. Clin. Immunol. Dec 2015 ORF Clones RC224203
CCDC103 DYX1C1 is required for axonemal dynein assembly and ciliary motility Nature Genetics doi:10.1038/ng.2707 ORF Clones RC208345
CCDC106 CCDC106 promotes non-small cell lung cancer cell proliferation Oncotarget 2017 ORF Clones RC201207
CCDC167 Identification of new transmembrane proteins concentrated at the nuclear envelope using organellar proteomics of mesenchymal cells bioRxiv 2018 ORF Clones MR221746
CCDC22 Missense variant in CCDC22 causes X-linked recessive intellectual disability with features of Ritscher-Schinzel/3C syndrome Eur. J. Hum. Genet. Jun 2014 ORF Clones RC201585
CCDC22 RME-8 coordinates the WASH complex with the retromer SNX-BAR dimer to control endosomal tubulation J. Cell. Sci. Mar 2014 ORF Clones RC201585
CCDC8 Coiled-coil domain-containing protein 8 inhibits the invasiveness and migration of non-small cell lung cancer cells Hum. Pathol. Jun 2016 ORF Clones RC206818
CCDC88A Girdin, an actin-binding protein, is critical for migration, adhesion and invasion of human glioblastoma cells J. Neurochem. July 2014 ORF Clones RC226549
CCL11 SNPs in inflammatory genes CCL11, CCL4 and MEFV in a fibromyalgia family study PLoS ONE 2018 ORF Clones RC204726
CCL2 Overexpression of the monocyte chemokine CCL2 in dorsal root ganglion neurons causes a conditioning-like increase in neurite outgrowth and does so via a STAT3 dependent mechanism Exp. Neurol 2016 ORF Clones MR226804
CCL2 CCL2 Mediates Neuron-Macrophage Interactions to Drive Proregenerative Macrophage Activation Following Preconditioning Injury J. Neurosci. Dec 2015 ORF Clones RN213382
CCL22 Engineering human stellate cells for beta cell replacement therapy promotes in vivo recruitment of regulatory T cells Materials Today Bio 2019 ORF Clones SC321689
CCL3 Transcriptional down-regulation of ccr5 in a subset of HIV+ controllers and their family members Elife 2019 ORF Clones RC210026
Ccl9 Saikosaponins A, C and D enhance liver-targeting effects of anticancer drugs by modulating drug transporters Oncotarget 2017 ORF Clones MG223660
CCM2 Cerebral cavernous malformations arise from endothelial gain of MEKK3-KLF2/4 signalling Nature Apr 2016 ORF Clones RC201418
CCNA2 Cyclin A2 and CDK2 as Novel Targets of Aspirin and Salicylic acid: a Potential Role in Cancer Prevention Mol. Cancer Res. Dec 2015 ORF Clones RC211148
CCNB1 Minute Virus of Mice (MVM) inhibits transcription of the cyclin B1 gene during infection J. Virol. 2017 ORF Clones MR206857
CCND1 ETV4 Facilitates Cell-Cycle Progression in Pancreatic Cells through Transcriptional Regulation of Cyclin D1 Mol. Cancer Res.2017 ORF Clones RC204957
CCND1 PAC exhibits potent anti-colon cancer properties through targeting cyclin D1 and suppressing epithelial-to-mesenchymal transition Mol. Carcinog. Jan 2015 ORF Clones RG204957
CCND2 The genomic landscape of core-binding factor acute myeloid leukemias Nat. Genet. 2016 ORF Clones RC210316
CCND2 De novo CCND2 mutations leading to stabilization of cyclin D2 cause megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome Nat. Genet. 510-5 46 5. May 2014 ORF Clones RC210316
CCNE1 Ccne1 Overexpression Causes Chromosome Instability in Liver Cells and Liver Tumor Development in Mice Gastroenterology 2019 ORF Clones MR226185
CCNE1 Gastrointestinal tumors, non-colorectal Ann. Onc., Sep 2012; 23: ix224 - ix257. ORF Clones RC204289
CCNK The Cyclin K/Cdk12 complex maintains genomic stability via regulation of expression of DNA damage response genes Genes & Dev., Oct 2011; 25: 2158 - 2172. ORF Clones
CD133 CD133 and DNA-PK regulate MDR1 via the PI3K- or Akt-NF-?B pathway in multidrug-resistant glioblastoma cells in vitro Oncogene Mar 2015 ORF Clones RC221611
CD163 Macrophage-specific nanotechnology-driven CD163 overexpression in human macrophages results in an M2 phenotype under inflammatory conditions Immunobiology 2017 ORF Clones RC208557
CD163 The New Role of CD163 in the Differentiation of Bone Marrow Stromal Cells into Vascular Endothelial-Like Cells Stem Cells International Jan 2016 ORF Clones RN206586
CD163 Replacing Heme with Paclitaxel to Prepare Drug-Loaded Globin Nanoassembles for CD163 Targeting J Pharm Sci Jan 2015 ORF Clones RG208557
CD177 Primary squamous cell carcinoma of the extrahepatic bile duct: A case report Gastroenterol Hepatol 2019 ORF Clones MR210799
CD200 Forced expression of CD200 improves the differentiation capability and immunoregulatory functions of mesenchymal stromal cells Biotechnol. Lett. 2018 ORF Clones RC206356
CD200 Preparation, characterization, and transfection efficiency of low molecular weight polyethylenimine-based nanoparticles for delivery of the plasmid encoding CD200 gene Int J Nanomedicine 2017 ORF Clones SC108879
CD200 CD200+ and CD200- macrophages accumulated in ischemic lesions of rat brain: The two populations cannot be classified as either M1 or M2 macrophages Journal of neuroimmunology May 2015 ORF Clones RN206783
CD200R1 CD200 Induces Epithelial-to-Mesenchymal Transition in Head and Neck Squamous Cell Carcinoma via β-Catenin-Mediated Nuclear Translocation Cancers (Basel) 2019 ORF Clones MR204778
CD200R1 Alterations in CD200-CD200R1 System during EAE Already Manifest at Presymptomatic Stages Front Cell Neurosci 2017 ORF Clones MR204778
CD200R1 Single amino acid substitution in LC-CDR1 induces Russell body phenotype that attenuates cellular protein synthesis through eIF2α phosphorylation and thereby downregulates IgG secretion despite operational secretory pathway traffic MAbs 2017 ORF Clones RC210223
CD207 Langerhans Cells Sense Staphylococcus aureus Wall Teichoic Acid through Langerin To Induce Inflammatory Responses MBio 2019 ORF Clones RC204669
CD207 A Common Genetic Variation in Langerin (CD207) Compromises Cellular Uptake of Staphylococcus aureus J Innate Immun 2019 ORF Clones RC204669
CD22 CD22-targeted CAR T cells induce remission in B-ALL that is naive or resistant to CD19-targeted CAR immunotherapy Nat. Med.2017 ORF Clones RC216939
CD24 Heparanase promotes glioma progression via enhancing CD24 expression Int. J. Cancer 2019 ORF Clones RC209542
CD24 CD24 Expression and differential resistance to chemotherapy in triple-negative breast cancer Oncotarget 2017 ORF Clones RG209542
CD24 Prostaglandin E2 receptor 4 mediates renal cell carcinoma intravasation and metastasis Cancer Lett 2017 ORF Clones RC209542
CD247 Adoptive transfer of murine T cells expressing a chimeric-PD1-Dap10 receptor as an immunotherapy for lymphoma Immunology 2017 ORF Clones MR201306
CD274 Tumor-intrinsic PD-L1 signals regulate cell growth, pathogenesis and autophagy in ovarian cancer and melanoma Cancer Res. 2016 ORF Clones MG203953
CD274 Human CAR T cells with cell-intrinsic PD-1 checkpoint blockade resist tumor-mediated inhibition. J. Clin. Invest. 2016 ORF Clones RC213071
CD274 The tumor suppressor miR-138-5p targets PD-L1 in colorectal cancer Oncotarget 2016 ORF Clones RC213071
CD274 The splicing FK506-binding protein-51 isoform plays a role in glioblastoma resistance through programmed cell death ligand-1 expression regulation Cell Death Discovery 2019 ORF Clones RG213071
CD274 Bispecific antibody approach for improved melanoma-selective PD-L1 immune checkpoint blockade J. Invest. Dermatol. 2019 ORF Clones RC213071
CD274 Identification and characterization of an alternative cancer-derived PD-L1 splice variant Cancer Immunol. Immunother. 2018 ORF Clones RC213071
CD274 Development of a PD-L1-Expressing Orthotopic Liver Cancer Model: Implications for Immunotherapy for Hepatocellular Carcinoma Liver Cancer 2018 ORF Clones MR203953
CD274 Control of PD-L1 expression by miR-140/142/340/383 and oncogenic activation of the OCT4-miR-18a pathway in cervical cancer Oncogene 2018 ORF Clones RC213071
CD274 Selection and characterization of the novel anti-human PD-1 FV78 antibody from a targeted epitope mammalian cell-displayed antibody library Cell. Mol. Immunol. 2016 ORF Clones RC213071
CD274 Abstract B136: Development of PD-L1/L2 over-expressing mouse liver cancer models to test the efficacy of anti-PD1 therapy for hepatocellular carcinoma Cancer Immunology Research Jan 2016 ORF Clones MR203953
CD276 B7H3 regulates differentiation and serves as a potential biomarker and theranostic target for human glioblastoma Lab. Invest. 2019 ORF Clones RC215291
CD28 Adoptive transfer of murine T cells expressing a chimeric-PD1-Dap10 receptor as an immunotherapy for lymphoma Immunology 2017 ORF Clones MR202454
CD28 A Quantitative Assessment of Costimulation and Phosphatase Activity on Microclusters in Early T Cell Signaling PLOS One October 30, 2013 ORF clones RG211318
CD2AP Role for a Cindr–Arf6 axis in patterning emerging epithelia Mol. Biol. Cell, Dec 2011; 22: 4513 - 4526. ORF Clones RC210191
CD33 Evidence for C1q-mediated crosslinking of CD33/LAIR-1 inhibitory immunoreceptors and biological control of CD33/LAIR-1 expression Sci Rep 2017 ORF Clones RC207023
CD33 Evidence for C1q-mediated crosslinking of CD33/LAIR-1 inhibitory immunoreceptors and biological control of CD33/LAIR-1 expression Sci Rep 2017 ORF Clones RC217716
CD34 Tunneling nanotubes mediate the transfer of stem cell marker CD133 between hematopoietic progenitor cells Exp. Hematol. 2016 ORF Clones RG204446
CD36 Fluorescent labelling of membrane fatty acid transporter CD36 (SR-B2) in the extracellular loop PLoS ONE 2019 ORF Clones RC221976
CD36 Ligand-induced growth and compaction of CD36 nanoclusters enriched in Fyn induces Fyn signaling J. Cell. Sci. 2016 ORF Clones RC221976
CD36 Selenoprotein K is required for palmitoylation of CD36 in macrophages: implications in foam cell formation and atherogenesis J. Leukoc. Biol., May 2013; 93: 771 - 780. ORF Clones RC221976
CD38 Contribution of Nrf2 to Atherogenic Phenotype Switching of Coronary Arterial Smooth Muscle Cells Lacking CD38 Gene Cell. Physiol. Biochem. Sep 2015 ORF Clones MG204265
CD38 Characterization of Streptococcus pyogenes ß-NAD+ Glycohydrolase: RE-EVALUATION OF ENZYMATIC PROPERTIES ASSOCIATED WITH PATHOGENESIS J. Biol. Chem., Feb 2010; 285: 5683 - 5694 ORF Clones RC203179
CD3D A novel method to generate T-cell receptor-deficient chimeric antigen receptor T cells Blood Adv 2018 ORF Clones RC210010
CD3D A novel method to generate T-cell receptor-deficient chimeric antigen receptor T cells Blood Adv 2018 ORF Clones RC217875
CD3E A novel method to generate T-cell receptor-deficient chimeric antigen receptor T cells Blood Adv 2018 ORF Clones RC208276
CD3G A novel method to generate T-cell receptor-deficient chimeric antigen receptor T cells Blood Adv 2018 ORF Clones RC220512
CD40LG A novel CD40LG deletion causes the hyper-IgM syndrome with normal CD40L expression in a 6-month-old child Immunol. Res. Mar 2015 ORF Clones RC210004
CD44 CD44s Assembles Hyaluronan Coat on Filopodia and Extracellular Vesicles and Induces Tumorigenicity of MKN74 Gastric Carcinoma Cells Cells 2019 ORF Clones RC221771
CD44 Homophilic CD44 interactions mediate tumor cell aggregation and polyclonal metastasis in patient-derived breast cancer models Cancer Discov 2018 ORF Clones RC221771
CD44 Impact of Surfactants on the Target Recognition of Fab-Conjugated PLGA Nanoparticles Eur J Pharm Biopharm 2018 ORF Clones RC212616
CD44 CD82 suppresses CD44 alternative splicing-dependent melanoma metastasis by mediating U2AF2 ubiquitination and degradation Oncogene Apr 2016 ORF Clones RC221771
CD44 CD44 Regulates Pancreatic Cancer Invasion through MT1-MMP Mol. Cancer Res. Jan 2015 ORF Clones MR226618
CD47 An unbiased in vivo functional genomics screening approach in mice identifies novel tumor cell-based regulators of immune rejection Cancer Immunol. Immunother. 2017 ORF Clones MR204706
Cd47 Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer Nature 2017 ORF Clones MG204706
CD55 Epidermal Growth Factor Receptor Targeting IgG3 Triggers Complement-Mediated Lysis of Decay-Accelerating Factor Expressing Tumor Cells through the Alternative Pathway Amplification Loop J. Immunol. Jun 2014 ORF Clones RC201615
CD59 Increased internalization of complement inhibitor CD59 may contribute to endothelial inflammation in obstructive sleep apnea Sci Transl Med Jan 2016 ORF Clones RC218343
CD63 A Ca2+-stimulated exosome release pathway in cancer cells is regulated by Munc13-4 J. Cell Biol. 2018 ORF Clones RC201733
CD63 High-throughput screening identified selective inhibitors of exosome biogenesis and secretion: A drug repurposing strategy for advanced cancer Sci Rep 2018 ORF Clones RG201733
CD63 Expression of MicroRNA-34a in Alzheimer's Disease Brain Targets Genes Linked to Synaptic Plasticity, Energy Metabolism, and Resting State Network Activity Brain Res. May 2016 ORF Clones RG201733
CD63 Inhibition of Oncogenic Epidermal Growth Factor Receptor Kinase Triggers Release of Exosome-like Extracellular Vesicles and Impacts Their Phosphoprotein and DNA Content J. Biol. Chem. Aug 2015 ORF Clones RG201733
CD63 Glypican-1 identifies cancer exosomes and detects early pancreatic cancer Nature Jun 2015 ORF Clones RG217238
CD63 Detachment of Breast Tumor Cells Induces Rapid Secretion of Exosomes Which Subsequently Mediate Cellular Adhesion and Spreading. PLoS One. 2011;6(9):e24234. doi: 10.1371/journal.pone.0024234. Epub 2011 Sep 6. ORF Clones RG201733
CD70 Single amino acid substitution in LC-CDR1 induces Russell body phenotype that attenuates cellular protein synthesis through eIF2α phosphorylation and thereby downregulates IgG secretion despite operational secretory pathway traffic MAbs 2017 ORF Clones RC200410
CD70 Combined immunodeficiency and Epstein-Barr virus-induced B cell malignancy in humans with inherited CD70 deficiency. J. Exp. Med 2017 ORF Clones RC200410
CD70 Characterization of the human T cell response to in vitro CD27 costimulation with varlilumab Journal for ImmunoTherapy of Cancer Aug 2015 ORF Clones RC200410
Cd74 The E3 ubiquitin ligase RNF114 and TAB1 degradation are required for maternal-to-zygotic transition EMBO Rep 2017 ORF Clones MR225627
CD79a Anti-CD79 Antibody Induces B Cell Anergy That Protects against Autoimmunity J. Immunol., Jan 2014. ORF Clones MG202501
CD79B CD79B limits response of diffuse large B cell lymphoma to ibrutinib Leuk. Lymphoma Dec 2015 ORF Clones RG215340
CD81 Hepatitis C Virus (HCV) Mimics Effects of Glypican-3 (GPC3) on CD81 and Promotes Development of Hepatocellular Carcinomas via Activation of Hippo Pathway in Hepatocytes Am. J. Pathol. 2018 ORF Clones RC217508
CD82 CD82 suppresses CD44 alternative splicing-dependent melanoma metastasis by mediating U2AF2 ubiquitination and degradation Oncogene Apr 2016 ORF Clones RC200457
CD86 Live cell superresolution-structured illumination microscopy imaging analysis of the intercellular transport of microvesicles and costimulatory proteins via nanotubes between immune cells Methods Appl. Fluoresc. 2018 ORF Clones RG217341
CD86 Transient Acceleration of Epidermal Growth Factor Receptor Dynamics Produces Higher-Order Signaling Clusters J. Mol. Biol. 2018 ORF Clones RC217341
CD86 DOCK8 enforces immunological tolerance by promoting IL-2 signaling and immune synapse formation in Tregs JCI Insight 2017 ORF Clones RG217341
CD8A Analysis of herpes simplex type 1 gB, gD, and gH/gL on production of infectious HIV-1: HSV-1 gD restricts HIV-1 by exclusion of HIV-1 Env from maturing viral particles Retrovirology 2019 ORF Clones RC206608
CD8A Gene-modified NK-92MI cells expressing a chimeric CD16-BB-ζ or CD64-BB-ζ receptor exhibit enhanced cancer-killing ability in combination with therapeutic antibody Oncotarget 2017 ORF Clones RC206608
CD9 VAMP-associated protein-A and oxysterol-binding protein-related protein 3 promote the entry of late endosomes into the nucleoplasmic reticulum J. Biol. Chem. 2018 ORF Clones RG202000
CD9 The HDAC6 Inhibitor Tubacin Induces Release of CD133(+) Extracellular Vesicles from Cancer Cells J. Cell. Biochem. 2017 ORF Clones RG202000
CD9 Tetraspanin CD9 determines invasiveness and tumorigenicity of human breast cancer cells Oncotarget Feb 2015 ORF Clones RG202000
CD9 The Nuclear Pool of Tetraspanin CD9 Contributes to Mitotic Processes in Human Breast Carcinoma Mol. Cancer Res. Aug 2014 ORF Clones RG202000
CD9 PNAS Plus: MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response PNAS, Jul 2012; 109: E2110 - E2116. ORF Clones RC202000
CD99 CerS6-Derived Sphingolipids Interact with Mff and Promote Mitochondrial Fragmentation in Obesity Cell 2019 ORF Clones RC204056
CD99 Ectodomain shedding of CD99 within highly conserved regions is mediated by the metalloprotease meprin ß and promotes transendothelial cell migration FASEB J 2016 ORF Clones RC204056
CD99L2 Ectodomain shedding of CD99 within highly conserved regions is mediated by the metalloprotease meprin ß and promotes transendothelial cell migration FASEB J 2016 ORF Clones RC207079
CDC25A miR-21-mediated Radioresistance Occurs via Promoting Repair of DNA Double Strand Breaks J. Biol. Chem. 2017 ORF Clones MR208257
CDC25A Human TRIB2 Oscillates during the Cell Cycle and Promotes Ubiquitination and Degradation of CDC25C Int J Mol Sci 2016 ORF Clones RC200496
CDC25A miRNA-497 Negatively Regulates the Growth and Motility of Chondrosarcoma Cells by Targeting Cdc25A Oncology Research Mar 2016 ORF Clones RC200496
CDC25A Akt-p53-miR-365-cyclin D1/cdc25A axis contributes to gastric tumorigenesis induced by PTEN deficiency Nat Commun. 2013 Oct 23;4:2544 ORF clones RG200496
CDC25B A novel microRNA, hsa-miR-6852 differentially regulated by Interleukin-27 induces necrosis in cervical cancer cells by downregulating the FoxM1 expression Sci Rep 2018 ORF Clones RG202246
CDC25B Human TRIB2 Oscillates during the Cell Cycle and Promotes Ubiquitination and Degradation of CDC25C Int J Mol Sci 2016 ORF Clones RC207409
CDC25B Conserved Molecular Factors: Role of the Snail Family of Transcription Factors and the Fat Family of Atypical Cadherins in Cortical Development Thesis Dec 2014 ORF Clones MR208736
Cdc25b Snail coordinately regulates downstream pathways to control multiple aspects of Mammalian neural precursor development J. Neurosci. 5164-75 34 15. April 2014 ORF Clones MR208736
CDC42 Induction of entosis in prostate cancer cells by nintedanib and its therapeutic implications Oncol Lett 2019 ORF Clones RC214076
CDC42 Glucose insult elicits hyperactivation of cancer stem cells through miR-424-cdc42-prdm14 signalling axis Br. J. Cancer 2017 ORF Clones RC214076
CDC42 shRNA mediated inhibition of Cdc42 gene expression in Calu-6 lung cancer cells bioRxiv 2017 ORF Clones RG214076
CDC42 Activation of the Wnt/Planar Cell Polarity Pathway Is Required for Pericyte Recruitment during Pulmonary Angiogenesis Am. J. Pathol. Nov 2014 ORF Clones RG214076
CDC42 RhoJ is an endothelial cell-restricted Rho GTPase that mediates vascular morphogenesis and is regulated by the transcription factor ERG Blood, Jul 2011; 118: 1145 - 1153. ORF Clones RC214076
Cdc42ep1 Large-Scale Discovery of ERK2 Substrates Identifies ERK-Mediated Transcriptional Regulation by ETV3 Sci. Signal., Oct 2011; 4: rs11. ORF Clones MR206427
CDC42EP4 Phosphorylation of Cdc42 Effector Protein-4 (CEP4) by Protein Kinase C Promotes Motility of Human Breast Cells J. Biol. Chem. Aug 2014 ORF Clones RC201162
CDC7 p53 controls CDC7 levels to reinforce G1 cell cycle arrest upon genotoxic stress Cell Cycle 2016 ORF Clones RG210742
CDC7 Molecular architecture of the DNA replication origin activation checkpoint The EMBO Journal (20 August 2010) doi:10.1038/emboj.2010.201 Article ORF Clones RC205417
CDC73 Large intragenic deletion of CDC73 (exons 4-10) in a three-generation hyperparathyroidism-jaw tumor (HPT-JT) syndrome family BMC Med. Genet. 2017 ORF Clones RC209479
CDC73 Characterization of a New CDC73 Missense Mutation that Impairs Parafibromin Expression and Nucleolar Localization PLoS ONE May 2014 ORF Clones RG209479
CDCP1 FBXL14 abolishes breast cancer progression by targeting CDCP1 for proteasomal degradation Oncogene 2018 ORF Clones RC220633
CDH Overexpression of CASS4 promotes invasion in non-small cell lung cancer by activating the AKT signaling pathway and inhibiting E-cadherin expression Tumour Biol. 2016 ORF Clones RC220731
CDH1 Induced Tamoxifen Resistance is Mediated by Increased Methylation of E-Cadherin in Estrogen Receptor-Expressing Breast Cancer Cells Sci Rep 2019 ORF Clones RC220731
CDH1 miR-25 promotes invasion of human non-small cell lung cancer via CDH1 Bioengineered 2019 ORF Clones RC220731
CDH1 Synergistic antitumor activity of aspirin and erlotinib: Inhibition of p38 enhanced aspirin plus erlotinib-induced suppression of metastasis and promoted cancer cell apoptosis Oncol Lett 2018 ORF Clones RG220731
CDH1 Simultaneous NF-?B inhibition and E-cadherin upregulation mediate mutually synergistic anticancer activity of celastrol and SAHA in vitro and in vivo Int. J. Cancer Feb 2014 ORF Clones RG220731
CDH1 microRNA-92a Promotes Lymph Node Metastasis of Human Esophageal Squamous Cell Carcinoma via E-Cadherin J. Biol. Chem., Mar 2011; 286: 10725 - 10734 ORF Clones RC220731
CDH11 Cadherin 11 Involved in Basement Membrane Damage and Dermal Changes in Melasma Acta Derm Venereol Dec 2015 ORF Clones RC203810
CDH13 Severe fever with thrombocytopenia syndrome phlebovirus non-structural protein activates TPL2 signalling pathway for viral immunopathogenesis Nat Microbiol 2019 ORF Clones RC206068
CDH17 Data on the function of CDH17 in pancreatic cancer growth Data in Brief 2019 ORF Clones RC211298
CDH17 Graphene quantum dots-functionalized multi-walled carbon nanotubes as nanocarriers in electrochemical immunosensing. Determination of IL-13 receptor α2 in colorectal cells and tumor tissues with different metastatic potential Sensors and Actuators B: Chemical 2019 ORF Clones RC211298
CDH17 Disruption of oncogenic liver-intestine cadherin (CDH17) drives apoptotic pancreatic cancer death Cancer Lett. 2019 ORF Clones MR210847
CDH17 Disruption of oncogenic liver-intestine cadherin (CDH17) drives apoptotic pancreatic cancer death Cancer Lett. 2019 ORF Clones RC211298
CDH17 Determination of cadherin-17 in tumor tissues of different metastatic grade using a single incubation-step amperometric immunosensor Anal. Chem. 2018 ORF Clones RC211298
CDH17 Cadherin 17 is related to recurrence and poor prognosis of cytokeratin 19‑positive hepatocellular carcinoma Oncology Letter 2017 ORF Clones RC211298
CDH17 Nuclear factor I-C (NFIC) Regulates Dentin Sialophosphoprotein (DSPP) and E-cadherin via Control of Kruppel-like factor 4 (KLF4) during Dentinogenesis J. Biol. Chem. Aug 2014 ORF Clones RC211298
CDH3 HOXA9 promotes homotypic and heterotypic cell interactions that facilitate ovarian cancer dissemination via its induction of P-cadherin Mol. Cancer July 2014 ORF Clones RC207346
CDH5 Vascular Endothelial-cadherin plays a role in regulating the Norrin-FZD4 pathway and can cause Familial Exududative-vitroretinopathy (FEVR) Thesis Apr 2015 ORF Clones RC223907
CDH8 Ectopic expression of cadherin 8 is sufficient to cause cyst formation in a novel 3D collagen matrix renal tubule culture Am J Physiol Cell Physiol, Jul 2011; 301: C99 - C105. ORF Clones RC217249
CDK1 Potent Activity of Composite Cyclin Dependent Kinase Inhibition against Hepatocellular Carcinoma Cancers (Basel) 2019 ORF Clones RC200495
CDK1 Spatiotemporal control of mitotic exit during anaphase by an aurora B-Cdk1 crosstalk Elife 2019 ORF Clones RG200495
CDK1 The Role of p27Kip1 in Dasatinib-Enhanced Paclitaxel Cytotoxicity in Human Ovarian Cancer Cells J Natl Cancer Inst, Sep 2011; 103: 1403 - 1422. ORF Clones RC211402
CDK1 The Role of p27Kip1 in Dasatinib-Enhanced Paclitaxel Cytotoxicity in Human Ovarian Cancer Cells J Natl Cancer Inst, Aug 2011; 10.1093/jnci/djr280. ORF Clones RC200495
CDK11B Androgen receptor is a potential novel prognostic marker and oncogenic target in osteosarcoma with dependence on CDK11 Sci Rep 2017 ORF Clones RC216465
CDK14 Discovery of Covalent CDK14 Inhibitors with Pan-TAIRE Family Specificity Cell Chem Biol 2019 ORF Clones RC224426
CDK19 Conversion of antigen-specific effector/memory T cells into Foxp3-expressing Treg cells by inhibition of CDK8/19 Sci Immunol 2019 ORF Clones MR215712
CDK2 CDK2 kinase activity is a regulator of male germ cell fate bioRxiv 2019 ORF Clones RC200494
CDK20 Fibroblast growth factor receptor influences primary cilium length through an interaction with intestinal cell kinase Proc. Natl. Acad. Sci. U.S.A. 2019 ORF Clones RC214191
CDK4 LEM4 confers tamoxifen resistance to breast cancer cells by activating cyclin D-CDK4/6-Rb and ERα pathway Nat Commun 2018 ORF Clones RC201156
CDK4 miR-6883 family miRNAs target CDK4/6 to induce G1 phase cell cycle arrest in colon cancer cells Cancer Res. 2017 ORF Clones MG204246
CDK4 Combined CDK4/6 and mTOR inhibition is synergistic against glioblastoma via multiple mechanisms Clin. Cancer Res. 2017 ORF Clones RC401060
CDK5R2 Cell cycle-dependent ubiquitylation and destruction of NDE1 by CDK5-FBW7 regulates ciliary length EMBO J. Jul 2015 ORF Clones MG216908
CDK5RAP1 The CDK5 repressor CDK5RAP1 is a methylthiotransferase acting on nuclear and mitochondrial RNA Nucleic Acids Res., Jul 2012; 40: 6235 - 6240. ORF Clones RC216600
CDK8 Conversion of antigen-specific effector/memory T cells into Foxp3-expressing Treg cells by inhibition of CDK8/19 Sci Immunol 2019 ORF Clones MR218219
CDK9 Potent Activity of Composite Cyclin Dependent Kinase Inhibition against Hepatocellular Carcinoma Cancers (Basel) 2019 ORF Clones RC201603
CDKL2 Loss of cyclin-dependent kinase-like 2 predicts poor prognosis in gastric cancer, and its overexpression suppresses cells growth and invasion Cancer Med 2018 ORF Clones RC510780
CDKN1A A Novel Inhibitor of Topoisomerase I Is Selectively Toxic for a Subset of Non-Small Cell Lung Cancer Cell Lines Mol. Cancer Ther 2016 ORF Clones RC201765
CDKN1A Genome-scale CRISPR activation screening identifies a role of ELAVL2-CDKN1A axis in paclitaxel resistance in esophageal squamous cell carcinoma Am J Cancer Res 2019 ORF Clones RC201765
CDKN1A A cmap-enabled gene expression signature-matching approach identifies small-molecule inducers of accelerated cell senescence BMC Genomics 2019 ORF Clones RC201765
CDKN1A Synuclein gamma expression enhances radiation resistance of breast cancer cells Oncotarget 2018 ORF Clones SR300740
CDKN1A Loss of the Cyclin-Dependent Kinase Inhibitor 1 in the Context of Brachyury-Mediated Phenotypic Plasticity Drives Tumor Resistance to Immune Attack Front Oncol 2018 ORF Clones RC201765
CDKN1A Expression Signatures of the Lipid-Based Akt Inhibitors Phosphatidylinositol Ether Lipid Analogues in NSCLC Cells Mol. Cancer Ther., Jul 2011; 10: 1137 - 1148. ORF Clones RC201817
CDKN1B p27/Kip1 functions as a tumor suppressor and oncoprotein in osteosarcoma Sci Rep 2019 ORF Clones RC201661
CDKN2A Estrogen receptor α promotes Cav1.2 ubiquitination and degradation in neuronal cells and in APP/PS1 mice Aging Cell 2019 ORF Clones MR201412
CDKN2A Direct CDKN2 Modulation of CDK4 Alters Target Engagement of CDK4 Inhibitor Drugs Mol. Cancer Ther. 2019 ORF Clones RC220937
CDKN2A A polymorphic variant in p19Arf confers resistance to chemically-induced skin tumors by activating the p53 pathway J. Invest. Dermatol. 2019 ORF Clones RC220937
CDKN2A CDKN2A/p16 deletion in head and neck cancer cells is associated with Cdk2 activation, replication stress, and vulnerability to Chk1 inhibition Cancer Res. 2017 ORF Clones RC220937
CDKN2B MicroRNA-17-92 cluster promotes the proliferation and the chemokine production of keratinocytes: implication for the pathogenesis of psoriasis Cell Death Dis 2018 ORF Clones RC204895
CDKN2B CDKN2B is critical for verapamil-mediated reversal of doxorubicin resistance in hepatocellular carcinoma Oncotarget 2017 ORF Clones RG204895
CDKN3 The tumor suppressor CDKN3 controls mitosis J. Cell Biol., Jun 2013; 201: 997 - 1012. ORF Clones RC213080
CDR2 CDR2L Is the Major Yo Antibody Target in Paraneoplastic Cerebellar Degeneration Ann. Neurol. 2019 ORF Clones RG204900
CDR2 Paraneoplastic syndrome-associated neuronal antibodies in adult ADHD Journal of Neuroimmunology Nov 2015 ORF Clones RG204900
CDR2L CDR2L Is the Major Yo Antibody Target in Paraneoplastic Cerebellar Degeneration Ann. Neurol. 2019 ORF Clones RC206909
CDR2L Paraneoplastic syndrome-associated neuronal antibodies in adult ADHD Journal of Neuroimmunology Nov 2015 ORF Clones RC206909
CDX2 Glucose-dependent Insulinotropic Polypeptide Mediated Signaling Pathways Enhance Apical PepT1 Expression in Intestinal Epithelial Cells Am. J. Physiol. Gastrointest. Liver Physiol. Nov 2014 ORF Clones RN209439
CEACAM-1 INPP5E regulates phosphoinositide-dependent cilia transition zone function. J. Cell Biol 2017 ORF Clones MG225456
CEBPA Induction of Selenoprotein P mRNA during Hepatitis C Virus Infection Inhibits RIG-I-Mediated Antiviral Immunity Cell Host Microbe 2019 ORF Clones RC218955
CEBPA Discovering metabolic disease gene interactions by correlated effects on cellular morphology Mol Metab 2019 ORF Clones RG218955
CEBPA C/EBP-α, involvement of a novel transcription factor in leptin-induced VCAM-1 production in mouse chondrocytes FEBS Letters, Feb 2014. ORF Clones RC218955
CEBPB Targeting Degradation of the Transcription Factor C/EBPβ Reduces Lung Fibrosis by Restoring Activity of the Ubiquitin-Editing Enzyme A20 in Macrophages Immunity 2019 ORF Clones MR227563
CEBPB PRMT7 deficiency enhances adipogenesis through modulation of C/EBP-β Biochem. Biophys. Res. Commun. 2019 ORF Clones MR227563
CEBPB C/EBPβ Is a Transcriptional Regulator of Wee1 at the G2/M Phase of the Cell Cycle Cells. 2019 ORF Clones RC205882
Cebpb The transcription factor NR4A3 controls CD103+ dendritic cell migration J. Clin. Invest. 2016 ORF Clones MR227563
CELA1 Role for Cela1 in Postnatal Lung Remodeling and AAT-deficient Emphysema Am. J. Respir. Cell Mol. Biol. 2018 ORF Clones MR203526
CELA1 Role Of Chymotrypsin-Like Elastase 1 In Lung Physiology And in α1-Antitrypsin Deficiency bioRxiv 2017 ORF Clones MR203526
CELF1 Cooperative repression of IGF2R translation by miR-195 and RNA-binding protein CUGBP1 Mol. Cell. Biol. 2017 ORF Clones RC206275
CELF1 Olive Oil-Supplemented Lipid Emulsion Induces CELF1 Expression and Promotes Apoptosis in Caco-2 Cells Cell. Physiol. Biochem 2017 ORF Clones RC206275
CELSR1 Genetic analysis of rare coding mutations of CELSR1-3 in congenital heart and neural tube defects in Chinese people Clinical Science 2016 ORF Clones RC211652
CELSR1 Genetic analysis of rare coding mutations in CELSR1-3 in Chinese Congenital Heart and Neural Tube Defects Clin. Sci. 2016 ORF Clones RC211652
CELSR2 Planar cell polarity gene Fuz triggers apoptosis in neurodegenerative disease models EMBO Rep. 2018 ORF Clones RC211860
CEMIP A modified flavonoid accelerates oligodendrocyte maturation and functional remyelination Glia 2019 ORF Clones MR217955
CEP250 Novel Candidate Genes and a Wide Spectrum of Structural and Point Mutations Responsible for Inherited Retinal Dystrophies Revealed by Exome Sequencing PLoS ONE 2016 ORF Clones RC213542
CER1 A selective inhibitor of ceramide synthase 1 reveals a novel role in fat metabolism Nat Commun 2018 ORF Clones RC210111
CERS2 LASS2 regulates invasion and chemoresistance via ERK/Drp1 modulated mitochondrial dynamics in bladder cancer cells J Cancer 2018 ORF Clones RC215300
CERS2 The ceramide synthase 2b gene mediates genomic sensing and regulation of sphingosine levels during zebrafish embryogenesis Elife 2017 ORF Clones RG215300
CERS2 miR-9 promotes cell proliferation and inhibits apoptosis by targeting LASS2 in bladder cancer Tumour Biol. Jul 2015 ORF Clones RC215300
CERS6 Ceramide synthase 6 predicts the prognosis of human gastric cancer: It functions as an oncoprotein by dysregulating the SOCS2/JAK2/STAT3 pathway Mol. Carcinog. 2018 ORF Clones RC219555
CES1 Protein O-GlcNAcylation Is Essential for the Maintenance of Renal Energy Homeostasis and Function via Lipolysis during Fasting and Diabetes J. Am. Soc. Nephrol. 2019 ORF Clones RC220398
CES1 Reduced carboxylesterase 1 is associated with endothelial injury in methamphetamine-induced pulmonary arterial hypertension Am. J. Physiol. Lung Cell Mol. Physiol. 2017 ORF Clones RC220398
CES1 Interaction of the Serine Hydrolase KIAA1363 with Organophosphorus Agents: Evaluation of Potency and Kinetics Archives of Biochemistry and Biophysics Jan 2016 ORF Clones RC220398
CES2 Carboxylesterase-2-Selective Two-Photon Ratiometric Probe Reveals Decreased Carboxylesterase-2 Activity in Breast Cancer Cells Anal. Chem. 2018 ORF Clones RC203009
CES2G Lipopolysaccharide Suppresses Carboxylesterase 2g Activity and 2-Arachidonylglycerol Hydrolysis: A Possible Mechanism to Regulate Inflammation Prostaglandins Other Lipid Mediat. Sep 2015 ORF Clones MR208876
CETN2 Mosaic-variegated aneuploidy syndrome mutation or haploinsufficiency in Cep57 impairs tumor suppression J. Clin. Invest. 2018 ORF Clones MR201474
Cfl1 The WD40-domain containing protein CORO2B is specifically enriched in glomerular podocytes and regulates the ventral actin cytoskeleton Sci Rep 2017 ORF Clones MG201348
CFL1 S-nitrosylation of cofilin-1 mediates estradiol-17ß-stimulated endothelial cytoskeleton remodeling Mol. Endocrinol. Mar 2015 ORF Clones RC203585
CFL1 S-nitrosylation of Cofilin-1 Serves as a Novel Pathway for VEGF-stimulated Endothelial Cell Migration J. Cell. Physiol. July 2014 ORF Clones RC203585
CFL1 S-nitrosylation of Cofilin-1ServesQ1 as a Novel Pathway forVEGF-Stimulated Endothelial CellMigration J. Cell. Physiol Jun 2014 ORF Clones RC203585
CFL1 LRRK2 regulates synaptogenesis and dopamine receptor activation through modulation of PKA activity Nat. Neurosci., Feb 2014. ORF Clones RG203585
CFLAR Vitamin E δ-tocotrienol sensitizes human pancreatic cancer cells to TRAIL-induced apoptosis through proteasome-mediated down-regulation of c-FLIPs Cancer Cell Int. 2019 ORF Clones RG200608
CFLAR cFLIP critically modulates apoptotic resistance in epithelial-to-mesenchymal transition Oncotarget 2017 ORF Clones RC200608
CGAS STAG2 deficiency induces interferon responses via cGAS-STING pathway and restricts virus infection Nat Commun 2018 ORF Clones RC212386
CH25H 25-hydroxycholesterol Production by Interferon Stimulated Gene Cholesterol-25-hydroxylase Restricts Mammalian Reovirus Infection J. Virol. 2018 ORF Clones RC204716
CH25H 25-Hydroxycholesterol Inhibition of Lassa Virus Infection through Aberrant GP1 Glycosylation MBio 2016 ORF Clones RC204716
CHAC1 Redistribution of EC-SOD resolves bleomycin-induced inflammation via increased apoptosis of recruited alveolar macrophages FASEB J. 2019 ORF Clones RC200912
CHAC1 Helicobacter pylori induces somatic mutations in TP53 via overexpression of CHAC1 in infected gastric epithelial cells FEBS Open Bio 2018 ORF Clones RC200912
CHAD Tracing Tumor Evolution in Sarcoma Reveals Clonal Origin of Advanced Metastasis Cell Rep 2019 ORF Clones MR205471
CHAF1A Regulation of oxidized base damage repair by chromatin assembly factor 1 subunit A Nucleic Acids Res. 2016 ORF Clones RC209138
CHAF1B Regulation of oxidized base damage repair by chromatin assembly factor 1 subunit A Nucleic Acids Res. 2016 ORF Clones RC202858
CHCHD2 Varied pathological and therapeutic response effects associated with CHCHD2 mutant and risk variants Hum. Mutat. 2017 ORF Clones RC209806
CHD2 Mutations in CHD2 cause defective association with active chromatin in chronic lymphocytic leukemia Blood Jun 2015 ORF Clones RC224580
CHD4 Defeating EpCAM(+) liver cancer stem cells by targeting chromatin remodeling enzyme CHD4 in human hepatocellular carcinoma J. Hepatol. Jun 2015 ORF Clones RG224232
CHEK2 RA-Induced Transcriptional Silencing of Checkpoint Kinase-2 through Promoter Methylation by Dnmt3b Is Required for Neuronal Differentiation of P19 Cells J. Mol. Biol. 2017 ORF Clones RC201278
CHFR Association of CHFR Promoter Methylation with Treatment Outcomes of Irinotecan-Based Chemotherapy in Metastatic Colorectal Cancer Neoplasia 2019 ORF Clones RC228526
CHFR A Generic Platform for Cellular Screening Against Ubiquitin Ligases Sci Rep Jan 2016 ORF Clones RC228465
CHGA Chromogranin A regulates neuroblastoma proliferation and phenotype Biol Open 2019 ORF Clones RC200492
CHKA Human Choline Kinase-a Promotes Hepatitis C Virus RNA Replication through Modulating Membranous Viral Replication Complex Formation J. Virol. 2016 ORF Clones RC207209
CHMP4B ATG12-ATG3 interacts with Alix to promote basal autophagic flux and late endosome function Nat. Cell Biol. Mar 2015 ORF Clones RC207637
CHRDL1 BMP4 and BMP antagonists regulate human white and beige adipogenesis Diabetes Jan 2015 ORF Clones RC202635
Chrdl1 Stage-Specific Modulation of Cortical Neuronal Development by Mmu-miR-134 Cereb Cortex, Jan 2011; 10.1093/cercor/bhq262 ORF Clones MR204928
CHRFAM7A Global proteomic profiling of the uniquely human CHRFAM7A gene in transgenic mouse brain Gene 2019 ORF Clones RC215588
CHRFAM7A Uniquely human CHRFAM7A gene increases the hematopoietic stem cell reservoir in mice and amplifies their inflammatory response Proc. Natl. Acad. Sci. U.S.A. 2019 ORF Clones RC215588
CHRFAM7A CHRFAM7A: a human-specific a7-nicotinic acetylcholine receptor gene shows differential responsiveness of human intestinal epithelial cells to LPS FASEB J. Feb 2015 ORF Clones RC215588
CHRM2 Comparison and evaluation of antimuscarinic and anti-inflammatory effects of five Bulbus fritillariae species based on UPLC-Q/TOF integrated dual-luciferase reporter assay, PCA and ANN analysis J. Chromatogr. B Analyt. Technol. Biomed. Life Sci 2016 ORF Clones RC212791
CHRM3 Comparison and evaluation of antimuscarinic and anti-inflammatory effects of five Bulbus fritillariae species based on UPLC-Q/TOF integrated dual-luciferase reporter assay, PCA and ANN analysis J. Chromatogr. B Analyt. Technol. Biomed. Life Sci 2016 ORF Clones RC212436
CHRM3 Muscarinic Receptor Activation Increases hERG Channel Expression through Phosphorylation of Ubiquitin Ligase Nedd4-2 Mol. Pharmacol. 877-86 85 6. March 2014 ORF Clones RC212436
CHRNA2 Muscarinic M5receptors modulate ethanol seeking in rats Neuropsychopharmacology 2018 ORF Clones RR214926
CHRNA3 The regulatory effect of Alisma Rhizomes and their triterpenoids on a3ß4 nicotinic acetylcholine receptor activity Oriental Pharmacy and Experimental Medicine 2016 ORF Clones RC212582
CHRNA3 Nicotine Activates YAP1 through nAChRs Mediated Signaling in Esophageal Squamous Cell Cancer (ESCC) PLoS ONE Mar 2014 ORF Clones RG212582
CHRNA4 Flupyrimin: A Novel Insecticide Acting at the Nicotinic Acetylcholine Receptors J. Agric. Food Chem. 2017 ORF Clones RR211661
CHRNA6 High-Throughput Patch Clamp Screening in Human α6-Containing Nicotinic Acetylcholine Receptors SLAS Discov 2017 ORF Clones RC204868
CHRNB2 High-Throughput Patch Clamp Screening in Human α6-Containing Nicotinic Acetylcholine Receptors SLAS Discov 2017 ORF Clones RC210408
CHRNB3 High-Throughput Patch Clamp Screening in Human α6-Containing Nicotinic Acetylcholine Receptors SLAS Discov 2017 ORF Clones RC210221
CHRNB3 The regulatory effect of Alisma Rhizomes and their triterpenoids on a3ß4 nicotinic acetylcholine receptor activity Oriental Pharmacy and Experimental Medicine 2016 ORF Clones RC210221
CHRNE Structure-Activity Relationships of Pan-Gαq/11 Coupled Muscarinic Acetylcholine Receptor Positive Allosteric Modulators ACS Chem Neurosci 2018 ORF Clones RC221423
CHT Impaired Presynaptic High-Affinity Choline Transporter Causes a Congenital Myasthenic Syndrome with Episodic Apnea Am. J. Hum. Genet. 2016 ORF Clones RC224138
CIB1 The human CIB1–EVER1–EVER2 complex governs keratinocyte-intrinsic immunity to β-papillomaviruses J. Exp. Med. 2018 ORF Clones RC201591
CIP1 Asiatic Acid Promotes p21WAF1/CIP1 Protein Stability through Attenuation of NDR1/2 Dependent Phosphorylation of p21WAF1/ CIP1 in HepG2 Human Hepatoma Cells Asian Pac. J. Cancer Prev. Feb 2014 ORF Clones RC201765
Cip2a Cip2a promotes cell cycle progression in triple-negative breast cancer cells by regulating the expression and nuclear export of p27Kip1 Oncogene 2016 ORF Clones SC311317
CIP2a Temsirolimus enhances the efficacy of cetuximab in colon cancer through a CIP2A-dependent mechanism J. Cancer Res. Clin. Oncol., Feb 2014. ORF Clones RC219918
CIRBP Cold-inducible RNA-binding protein (CIRP) triggers inflammatory responses in hemorrhagic shock and sepsis Genes & Dev., Aug 2013; 27: 1809 - 1820. ORF Clones RG201639
CISD1 Quantitative Proteomics of Presynaptic Mitochondria Reveal an Overexpression and Biological Relevance of Neuronal MitoNEET in Postnatal Brain Development Dev Neurobiol 2019 ORF Clones RC203308
CISD1 Efavirenz induces neuronal autophagy and mitochondrial alterations J. Pharmacol. Exp. Ther. Nov 2014 ORF Clones RC203308
CISH CISH is a negative regulator of IL-13-induced CCL26 production in lung fibroblasts Allergol Int 2018 ORF Clones RC206496
Cish Interaction of suppressor of cytokine signalling 3 with cavin-1 links SOCS3 function and cavin-1 stability Nat Commun 2018 ORF Clones MR203328
CITED2 Functional Analyses of a Novel CITED2 Nonsynonymous Mutation in Chinese Tibetan Patients with Congenital Heart Disease Pediatr Cardiol 2017 ORF Clones RC202494
CITED2 CITED2 Mutations in Conserved Regions Contribute to Conotruncal Heart Defects in Chinese Children DNA Cell Biol. 2017 ORF Clones RC202494
CKB Morphine Binds Creatine Kinase B and Inhibits Its Activity Front Cell Neurosci 2018 ORF Clones MR205953
claudin-2 Claudin-2 Expression Levels in Ulcerative Colitis: Development and Validation of an In-Situ Hybridisation Assay for Therapeutic Studies PLoS ONE 2016 ORF Clones RG204199
CLCN3 Novel CLC3 transcript variants in blood eosinophils and increased CLC3 expression in nasal lavage and blood eosinophils of asthmatics Immunity, Inflammation and Disease Dec 2014 ORF Clones RG214128
CLCN5 A Novel CLCN5 Mutation Associated With Focal Segmental Glomerulosclerosis and Podocyte Injury Kidney Int Rep 2018 ORF Clones RC217750
CLCN5 ATP Induces Conformational Changes in the Carboxyl-terminal Region of ClC-5 J. Biol. Chem., Feb 2011; 286: 6733 - 6741 ORF Clones RC217750
CLCN7 Lysosomal Storage and Albinism Due to Effects of a De Novo CLCN7 Variant on Lysosomal Acidification The American Journal of Human Genetics 2019 ORF Clones RC203450
CLCN7 A model of lysosomal pH regulation J. Gen. Physiol., May 2013; 141: 705 - 720. ORF Clones RC203450
CLDN1 Effects of Claudin-1 on the Action of Clostridium perfringens Enterotoxin in Caco-2 Cells Toxins (Basel) 2019 ORF Clones RC204466
Cldn1 Inducible Expression of Claudin-1 in Glomerular Podocytes Generates Aberrant Tight Junctions and Proteinuria through Slit Diaphragm Destabilization. J. Am. Soc. Nephrol 2016 ORF Clones MR225404
CLDN14 A variant in a Cis-regulatory element enhances claudin-14 expression and is associated with pediatric-onset hypercalciuria and kidney stones Hum. Mutat 2017 ORF Clones RC219687
CLDN15 Multiple claudin–claudin cis interfaces are required for tight junction strand formation and inherent flexibility Commun Biol 2018 ORF Clones MG202708
CLDN19 Abnormal Junctions and Permeability of Myelin in PMP22 Deficient Nerves Ann. Neurol. Dec 2013. ORF Clones RC216887
CLDN2 Caveolin 1 is Associated with Upregulated Claudin 2 in Necrotizing Enterocolitis Sci Rep 2019 ORF Clones RG204199
Cldn4 Claudin-4 is required for AMPK-modulated paracellular permeability in submandibular gland cells J Mol Cell Biol Dec 2014 ORF Clones RR210685
CLDN5 Claudin-5 regulates blood-brain barrier permeability by modifying brain microvascular endothelial cell proliferation, migration, and adhesion to prevent lung cancer metastasis CNS Neurosci Ther 2017 ORF Clones RC207122
Cldn6 Directed structural modification of Clostridium perfringens enterotoxin to enhance binding to claudin-5 Cell. Mol. Life Sci. Oct 2014 ORF Clones RN204021
CLDN7 Long Noncoding RNA SPRY4-IT1 Regulates Intestinal Epithelial Barrier Function by Modulating the Expression Levels of Tight Junction Proteins Mol. Biol. Cell Dec 2015 ORF Clones RC200530
CLDN9 A spontaneous metastasis model reveals the significance of claudin-9 overexpression in lung cancer metastasis Clin. Exp. Metastasis Dec 2015 ORF Clones MG202414
Cldn9 Directed structural modification of Clostridium perfringens enterotoxin to enhance binding to claudin-5 Cell. Mol. Life Sci. Oct 2014 ORF Clones RN205145
CLEC14A Methylation of CLEC14A is associated with its expression and lung adenocarcinoma progression J. Cell. Physiol. 2018 ORF Clones RC206655
CLEC16A The Autoimmune Disorder Susceptibility Gene CLEC16A Restrains NK Cell Function in YTS NK Cell Line and Clec16a Knockout Mice Front Immunol 2019 ORF Clones RC214696
CLEC16A Functional evaluation of the role of CLEC16A at the chromosome 16p13 locus Clin. Exp. Immunol. Nov 2013 ORF Clones RG214696
CLEC4A Dendritic cell immunoreceptor: A novel receptor for intravenous immunoglobulin mediates induction of regulatory T cells J. Allergy Clin. Immunol. Nov 2013 ORF Clones RG224937
CLEC4A2 Skin delivery of Clec4a small hairpin RNA elicited an effective antitumor response by enhancing CD8+ immunity in vivo Molecular Therapy: Nucleic Acids 2017 ORF Clones MR203449
CLIC1 The cellular chloride channels CLIC1 and CLIC4 contribute to virus-mediated cell motility J. Biol. Chem. 2018 ORF Clones RG218042
CLINT1 Visualization of Protein Sorting at the Trans-Golgi Network and Endosomes Through Super-Resolution Imaging Front Cell Dev Biol 2019 ORF Clones RC202387
CLN3 Claudin-3 is required for modulation of paracellular permeability by TNF-a through ERK1/2/slug signaling axis in submandibular gland Cell. Signal. Jul 2015 ORF Clones RR210721
CLN6 Gene Therapy Corrects Brain and Behavioral Pathologies in CLN6-Batten Disease Mol. Ther. 2019 ORF Clones RC201904
CLPP The mammalian homologue of yeast AFG1 ATPase (Lactation elevated 1) mediates degradation of nuclear-encoded complex IV subunits Biochem. J. Jan 2016 ORF Clones RC200301
CMAS A homozygous mutation in CMAS causes autosomal recessive intellectual disability in a Kazakh family Ann. Hum. Genet. 2019 ORF Clones RC223608
CMPK1 Identification of Human UMP/CMP Kinase 1 as Doxorubicin Binding Target Using Protein Microarray SLAS Discov 2017 ORF Clones RC204856
CMTM4 CMTM4 regulates angiogenesis by promoting cell surface recycling of VE-cadherin to endothelial adherens junctions Angiogenesis 2018 ORF Clones RC217697
CN9A Anomalous enhancement of resurgent Na+ currents at high temperatures by SCN9A mutations underlies the episodic heat-enhanced pain in inherited erythromelalgia Sci Rep 2019 ORF Clones RC224884
CNDP2 Family-wide Annotation of Enzymatic Pathways by Parallel In Vivo Metabolomics Cell Chem Biol 2019 ORF Clones MR207616
CNIH4 The protein secretion modulator TMED9 drives CNIH4/TGFα/GLI signaling opposing TMED3-WNT-TCF to promote colon cancer metastases Oncogene 2019 ORF Clones RC200050
CNOT3 Functional characterization of CNOT3 variants identified in familial adenomatous polyposis adenomas Oncotarget 2019 ORF Clones RC203795
CNOT4 MISTERMINATE Mechanistically Links Mitochondrial Dysfunction with Proteostasis Failure bioRxiv 2019 ORF Clones RC217418
CNOT4 Ubiquitination of ABCE1 by NOT4 in Response to Mitochondrial Damage Links Co-translational Quality Control to PINK1-Directed Mitophagy Cell Metab. 2018 ORF Clones RC217418
Cnot6l Loss of Git2 induces epithelial–mesenchymal transition by miR146a-Cnot6L-controlled expression of Zeb1 J. Cell Sci., Jun 2013; 126: 2740 - 2746. ORF Clones RG219766
CNPY3 RNA-Binding Protein HuR Regulates Paneth Cell Function by Altering Membrane Localization of TLR2 via Posttranscriptional Control of CNPY3 Gastroenterology 2019 ORF Clones MR203709
CNR1 Structure-Based Identification of Potent Natural Product Chemotypes as Cannabinoid Receptor 1 Inverse Agonists Molecules 2018 ORF Clones RC210397
CNR1 Secondary metabolites isolated fromPinus roxburghiiand interpretation of their cannabinoid and opioid binding properties by virtual screening andin vitrostudies Saudi Pharm J 2018 ORF Clones RC210397
CNR1 Development of a Δ9-Tetrahydrocannabinol Amino Acid-Dicarboxylate Prodrug With Improved Ocular Bioavailability Invest. Ophthalmol. Vis. Sci. 2017 ORF Clones RC210397
CNR1 Topical cannabinoid receptor 1 agonist attenuates the cutaneous inflammatory responses in oxazolone-induced atopic dermatitis model Int. J. Dermatol. Jun 2015 ORF Clones RC210397
CNR1 Flavonoids from Perovskia atriplicifolia and Their in Vitro Displacement of the Respective Radioligands for Human Opioid and Cannabinoid Receptors J. Nat. Prod. Jun 2015 ORF Clones RC210397
CNR1 The CB1 Cannabinoid Receptor Drives Corticospinal Motor Neuron Differentiation through the Ctip2/Satb2 Transcriptional Regulation Axis J. Neurosci., Nov 2012; 32: 16651 - 16665. ORF Clones SC327858
CNR2 Structure-Based Identification of Potent Natural Product Chemotypes as Cannabinoid Receptor 1 Inverse Agonists Molecules 2018 ORF Clones RC210224
CNR2 Secondary metabolites isolated fromPinus roxburghiiand interpretation of their cannabinoid and opioid binding properties by virtual screening andin vitrostudies Saudi Pharm J 2018 ORF Clones RC210224
CNR2 Development of a Δ9-Tetrahydrocannabinol Amino Acid-Dicarboxylate Prodrug With Improved Ocular Bioavailability Invest. Ophthalmol. Vis. Sci. 2017 ORF Clones RC210224
CNR2 Topical cannabinoid receptor 1 agonist attenuates the cutaneous inflammatory responses in oxazolone-induced atopic dermatitis model Int. J. Dermatol. Jun 2015 ORF Clones RC210224
CNR2 Flavonoids from Perovskia atriplicifolia and Their in Vitro Displacement of the Respective Radioligands for Human Opioid and Cannabinoid Receptors J. Nat. Prod. Jun 2015 ORF Clones RC210224
CNTN1 Chronic Inflammatory Demyelinating Polyneuropathy With Concurrent Membranous Nephropathy: An Anti-paranode and Podocyte Protein Antibody Study and Literature Survey Front Neurol 2018 ORF Clones RG220493
CNTN3 Molecular dissection of germline chromothripsis in a developmental context using patient-derived iPS cells Genome Med 2017 ORF Clones RG221979
CNTNAP2 Daratumumab treatment for therapy-refractory anti-CASPR2 encephalitis J. Neurol. 2019 ORF Clones RC210836
COA6 COA6 is a mitochondrial complex IV assembly factor critical for biogenesis of mtDNA-encoded COX2 Hum. Mol. Genet. Jul 2015 ORF Clones RC211054
COCH Different Phenotypes of the Two Chinese Probands with the Same c.889G>A (p.C162Y) Mutation in COCH Gene Verify Different Mechanisms Underlying Autosomal Dominant Nonsyndromic Deafness 9 PLoS ONE 2017 ORF Clones RC225944
COL1A1 Mass Spectrometry-Based Proteomics to Define Intracellular Collagen Interactomes Methods Mol. Biol. 2019 ORF Clones RC206234
COL1A1 A cysteine-based molecular code informs collagen C-propeptide assembly Nat Commun 2018 ORF Clones RC206234
Col1A2 Mass Spectrometry-Based Proteomics to Define Intracellular Collagen Interactomes Methods Mol. Biol. 2019 ORF Clones RC208484
COL1A2 Noncanonical autophagy at ER exit sites regulates procollagen turnover Proc. Natl. Acad. Sci. U.S.A. 2018 ORF Clones MR225252
COL1A2 A cysteine-based molecular code informs collagen C-propeptide assembly Nat Commun 2018 ORF Clones RC208484
COL1A2 αKlotho Mitigates Progression of AKI to CKD through Activation of Autophagy J. Am. Soc. Nephrol. 2016 ORF Clones MG225252
COL6 Annexin A2 mediates collagen VI secretion, pulmonary elasticity, and bronchial epithelial cell apoptosis J. Cell. Sci. Dec 2013. ORF Clones MG223027
COL6A1 Glycemic variability promotes both local invasion and metastatic colonization by pancreatic ductal adenocarcinoma Cellular and Molecular Gastroenterology and Hepatology 2018 ORF Clones MG223027
COMP Elevated Levels of Cartilage Oligomeric Matrix Protein during In Vitro Cartilage Matrix Generation Decrease Collagen Fibril Diameter Cartilage, Jul 2010; 1: 200 - 210 ORF Clones RC211080
COMT Identification of Potential Off-target Toxicity Liabilities of Catechol-O-methyltransferase Inhibitors by Differential Competition Capture Compound Mass Spectrometry J. Med. Chem. Apr 2016 ORF Clones RC204127
COP1 Ubiquitin Ligase COP1 Controls Hepatic Fat Metabolism by Targeting ATGL for Degradation Diabetes 2016 ORF Clones RC210492
COPA COPA mutations impair ER-Golgi transport and cause hereditary autoimmune-mediated lung disease and arthritis Nat. Genet. Apr 2015 ORF Clones RC214199
COPE Dissecting the Role of COPI Complexes in Influenza Virus Infection J. Virol., Mar 2013; 87: 2673 - 2685. ORF Clones RG203531
Coro1a Combination of cytoplasmic and nuclear girdin expression is an independent prognosis factor of breast cancer FASEB J. 2017 ORF Clones MR207361
Coro2b The WD40-domain containing protein CORO2B is specifically enriched in glomerular podocytes and regulates the ventral actin cytoskeleton Sci Rep 2017 ORF Clones MG207602
Cox-2 In vitro functional characterization of prostaglandin-endoperoxide synthase 2 during chondrocyte hypertrophic differentiation Oncotarget 2016 ORF Clones MR227684
COX7A2L COX7A2L Is a Mitochondrial Complex III Binding Protein that Stabilizes the III 2+ IV Supercomplex without Affecting Respirasome Formation Cell Reports 2016 ORF Clones RC202697
COX7A2L COX7A2L Is a Mitochondrial Complex III Binding Protein that Stabilizes the III 2+ IV Supercomplex without Affecting Respirasome Formation Cell Reports 2016 ORF Clones RG202697
CPAMD8 Molekulargenetische Untersuchungen zu Augenerkrankungen beim Holstein Friesian Rind Award 2017 ORF Clones RC213448
CPEB1 Altered splicing leads to reduced activation of CPEB3 in high-grade gliomas Oncotarget May 2016 ORF Clones RC208662
CPEB1 The WEE1 regulators CPEB1 and miR-15b switch from inhibitor to activators at G2/M Cell Cycle Mar 2016 ORF Clones RC208662
CPEB4 Functional Integration of mRNA Translational Control Programs Biomolecules Jul 2015 ORF Clones RC221803
CPNE7 Dentin sialophosphoprotein expression in enamel is regulated by Copine-7, a preameloblast-derived factor Arch. Oral Biol. 2017 ORF Clones RC206428
CPNE7 CPNE7, a preameloblast-derived factor, regulates odontoblastic differentiation of mesenchymal stem cells Biomaterials Oct 2014 ORF Clones RG206428
CPNE7 CPNE7, a preameloblast-derived factor, regulates odontoblastic differentiation of mesenchymal stem cells Biomaterials Oct 2014 ORF Clones RC206428
CPS1 Precision medicine in rare disease: Mechanisms of disparate effects of N-carbamyl-l-glutamate on mutant CPS1 enzymes Mol. Genet. Metab 2016 ORF Clones MR222149
CPSF2 JTE-607, a multiple cytokine production inhibitor, targets CPSF3 and inhibits pre-mRNA processing Biochem. Biophys. Res. Commun. 2019 ORF Clones RC209857
CPSF3 JTE-607, a multiple cytokine production inhibitor, targets CPSF3 and inhibits pre-mRNA processing Biochem. Biophys. Res. Commun. 2019 ORF Clones RC205834
CPT-1a An indispensable role of CPT-1a to survive cancer cells during energy stress through rewiring cancer metabolism Tumour Biol. 2016 ORF Clones RG221740
CPT1C Mutation in CPT1C Associated With Pure Autosomal Dominant Spastic Paraplegia JAMA Neurol Mar 2015 ORF Clones RG226726
CR1 Inhibitory effect of carbonyl reductase 1 against peritoneal progression of ovarian cancer: evaluation by ex vivo 3D-human peritoneal model Mol. Biol. Rep. 2019 ORF Clones RG216533
Cr1l Complement modulation in the retinal pigment epithelium rescues photoreceptor degeneration in a mouse model of Stargardt disease Proc. Natl. Acad. Sci. U.S.A 2017 ORF Clones MR207025
CRBP2 Abnormal Cannabidiol Modulates Vitamin A Metabolism by Acting as a Competitive Inhibitor of CRBP1 ACS Chem. Biol. 2019 ORF Clones RC217970
CREB1 FOXQ1 controls the induced differentiation of melanocytic cells Cell Death Differ. 2018 ORF Clones RC210577
CREB1 Downregulation of microRNA-27b-3p enhances tamoxifen resistance in breast cancer by increasing NR5A2 and CREB1 expression Cell Death Dis 2016 ORF Clones RC210577
CREB1 CREB Negatively Regulates IGF2R Gene Expression and Downstream Pathways to Inhibit Hypoxia-Induced H9c2 Cardiomyoblast Cell Death Int J Mol Sci Nov 2015 ORF Clones RC210577
CREB1 Rit-mediated Stress Resistance Involves a p38-Mitogen- and Stress-activated Protein Kinase 1 (MSK1)-dependent cAMP Response Element-binding Protein (CREB) Activation Cascade J. Biol. Chem., Nov 2012; 287: 39859 - 39868. ORF Clones RC210577
CREBBP P-glycoprotein attenuates DNA repair activity in multidrug-resistant cells by acting through the Cbp-Csk-Src cascade Oncotarget 2017 ORF Clones MG227381
CRH The nutrient and energy sensor Sirt1 regulates the hypothalamic-pituitary-adrenal (HPA) axis by altering the production of the prohormone convertase 2 (PC2) essential in the maturation of corticotropin releasing hormone (CRH) from its prohormone in male r J. Biol. Chem. Jan 2016 ORF Clones RC203144
CRHBP Tumor Specific Epigenetic Silencing of Corticotropin Releasing Hormone -Binding Protein in Renal Cell Carcinoma: Association of Hypermethylation and Metastasis PLoS ONE 2016 ORF Clones RC205258
Crhbp A Cortical Circuit for Sexually Dimorphic Oxytocin-Dependent Anxiety Behaviors Cell 2016 ORF Clones MR204660
CRHR2 Mast Cell CRF2 Suppresses Mast Cell Degranulation and Limits the Severity of Anaphylaxis and Stress-Induced Intestinal Permeability J. Allergy Clin. Immunol. 2018 ORF Clones RG222881
CRISPLD2 Crispld2 is required for neural crest cell migration and cell viability during zebrafish craniofacial development Genesis Aug 2015 ORF Clones RC214912
CRK Src-like adaptor protein 2 (SLAP2) binds to and inhibits FLT3 signaling Oncotarget 2016 ORF Clones MR204260
CRKL MiR-378 and MiR-1827 Regulate Tumor Invasion, Migration and Angiogenesis in Human Lung Adenocarcinoma by Targeting RBX1 and CRKL, Respectively Journal of Cancer 2018 ORF Clones RG208129
CRKL MicroRNA-320 inhibits invasion and induces apoptosis by targeting CRKL and inhibiting ERK and AKT signaling in gastric cancer cells Onco Targets Ther 2017 ORF Clones RC208129
CRKL CRKL overexpression promotes cell proliferation and inhibits apoptosis in endometrial carcinoma ONCOLOGY LETTERS 2016 ORF Clones RC208129
CRKL Crk-like adapter protein is overexpressed in cervical carcinoma, facilitates proliferation, invasion and chemoresistance, and regulates Src and Akt signaling Oncology Letters 2016 ORF Clones RC208129
Crkl Src-like adaptor protein 2 (SLAP2) binds to and inhibits FLT3 signaling Oncotarget 2016 ORF Clones MR225132
CRP CRP Stimulates GDF15 Expression in Endothelial Cells through p53 Mediators of Inflammation 2018 ORF Clones RC217269
CRTAP Transcriptome meta-analysis reveals a dysregulation in extra cellular matrix and cell junction associated gene signatures during Dengue virus infection Sci Rep 2016 ORF Clones RC200555
CRY1 Magnetoreception of Photoactivated Cryptochrome 1 in Electrochemistry and Electron Transfer ACS Omega 2018 ORF Clones RC207152
CRYAB Peripherally expressed misfolded proteins remotely disrupt brain function and aggravate stroke-induced brain injury bioRxiv 2019 ORF Clones MR201515
CRYAB MicroRNA-29 enhances autophagy and cleanses exogenous mutant αB-crystallin in retinal pigment epithelial cells Exp. Cell Res. 2019 ORF Clones RC202718
CSF3R The significance of G-CSF expression and myeloid-derived suppressor cells in the chemoresistance of uterine cervical cancer Scientific reports Dec2015 ORF Clones RG208790
CSMD1 Analysis of head and neck carcinoma progression reveals novel and relevant stage-specific changes associated with immortalisation and malignancy Sci Rep 2019 ORF Clones RC223813
Csnk1a1 Influence of a GSK3β phosphorylation site within the proximal C-terminus of Neurofilament-H on neurofilament dynamics Biol Open 2017 ORF Clones MR204736
CSNK1A1 Identification of a Tumor Specific, Active-Site Mutation in Casein Kinase 1a by Chemical Proteomics PLoS ONE Apr 2016 ORF Clones RC217936
CSNK1E Fibroblast Growth Factor Type 1 (FGF1)-Overexpressed Adipose-Derived Mesenchaymal Stem Cells (AD-MSC(FGF1)) Induce Neuroprotection and Functional Recovery in a Rat Stroke Model Stem Cell Rev 2017 ORF Clones RR20743
CSNK2A1 Protein kinase CK2 subunits exert specific and coordinated functions in skeletal muscle differentiation and fusogenic activity FASEB J. 2019 ORF Clones MR206103
CSPG4 Functional defects in Clostridium difficile TcdB toxin uptake identify CSPG4 receptor binding determinants J. Biol. Chem. 2017 ORF Clones RC218462
CSRP1 Quantitative proteomics reveals the roles of peroxisome-associated proteins in anti-viral innate immune responses Mol. Cell Proteomics Jun 2015 ORF Clones RC207109
CST3 Cystatin C promotes tau protein phosphorylation and causes microtubule instability by inhibiting intracellular turnover of GSK3β in neurons Mol. Cell. Neurosci. 2018 ORF Clones RC210730
CST3 Identification of Cystatin SA as a Novel Inhibitor of Acid Ceramidase J. Biol. Chem., Oct 2011; 286: 35624 - 35633. ORF Clones RC210730
CstB Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficits Brain, Jan 2011; 134: 258 - 277 ORF Clones MR221046
CSTF2 Regulation of Constitutive Tip110 Expression in Human Cord Blood CD34+Cells Through Selective Usage of the Proximal and Distal Polyadenylation Sites Within the 3'Untranslated Region Stem Cells Dev. 2018 ORF Clones RC204450
CTAG1B The Tumor Antigen NY-ESO-1 Mediates Direct Recognition of Melanoma Cells by CD4+ T Cells after Intercellular Antigen Transfer J. Immunol. Jan 2016 ORF Clones RC213318
CTBP1 The miR-644a/CTBP1/p53 axis suppresses drug resistance by simultaneous inhibition of cell survival and epithelial-mesenchymal transition in breast cancer Oncotarget 2016 ORF Clones RG208594
CTCF Prohibitin 1 Regulates the H19-Igf2 Axis and Proliferation in Hepatocytes J. Biol. Chem. 2016 ORF Clones MR210366
CTCFL BORIS/CTCFL-mediated transcriptional regulation of the hTERT telomerase gene in testicular and ovarian tumor cells Nucleic Acids Res., Sep 2010; 10.1093/nar/gkq827 ORF Clones RC216042
CTDSPL Control of PD-L1 expression by miR-140/142/340/383 and oncogenic activation of the OCT4-miR-18a pathway in cervical cancer Oncogene 2018 ORF Clones RC223937
CTGF CTGF mediates tumor-stroma interactions between hepatoma cells and hepatic stellate cells to accelerate HCC progression Cancer Res. 2018 ORF Clones RC210336
CTGF Cbx7 is epigenetically silenced in glioblastoma and inhibits cell migration by targeting YAP/TAZ-dependent transcription Sci Rep Jun 2016 ORF Clones RC210336
CTGF Expression of connective tissue growth factor in the livers of non-viral hepatocellular carcinoma patients with metabolic risk factors J. Gastroenterol. Jan 2016 ORF Clones RG210336
CTH Histone deacetylase 6 inhibitor tubastatin A attenuates angiotensin II-induced hypertension by preventing cystathionine γ-lyase protein degradation Pharmacol. Res. 2019 ORF Clones RC231191
CTH Two-Photon Fluorescent Probe for Detection of Exogenous and Endogenous Hydrogen Persulfide and Polysulfide in Living Organisms Anal. Chem. Feb 2015 ORF Clones RC202195
CTH Primary hepatocytes from mice lacking cysteine dioxygenase show increased cysteine concentrations and higher rates of metabolism of cysteine to hydrogen sulfide and thiosulfate Amino Acids Mar 2014 ORF Clones MR206244
CTLA4 Interferon-γ Signaling in Melanocytes and Melanoma Cells Regulates Expression of CTLA-4 Cancer Res. 2018 ORF Clones RC213631
CTLA4 CTLA4 promotes Tyk2-STAT3 dependent B cell oncogenecity Cancer Res. 2017 ORF Clones RG210150
CTNNA2 Cell-cell adhesion genes CTNNA2 and CTNNA3 are tumour suppressors frequently mutated in laryngeal carcinomas Nat Commun. 2013;4:2531. ORF clones RC208731
CTNNA3 Cell-cell adhesion genes CTNNA2 and CTNNA3 are tumour suppressors frequently mutated in laryngeal carcinomas Nat Commun. 2013;4:2531. ORF clones RC226241
CTNNB1 Canagliflozin inhibits growth of hepatocellular carcinoma via blocking glucose-influx-induced β-catenin activation Cell Death Dis 2019 ORF Clones RC208947
CTNNB1 Integrin α9 depletion promotes β-catenin degradation to suppress triple-negative breast cancer tumor growth and metastasis Int. J. Cancer 2019 ORF Clones RC208947
CTNNB1 Secreted frizzled-related protein 5 suppresses aggressive phenotype and reverses docetaxel resistance in prostate cancer J. Investig. Med. 2019 ORF Clones RC208947
CTNNB1 Odd-skipped related 1 inhibits lung cancer proliferation and invasion by reducing Wnt signaling through the suppression of SOX9 and β-catenin Cancer Sci. 2018 ORF Clones RC208947
CTNNB1 Comprehensive Molecular Profiling Identifies FOXM1 as a Key Transcription Factor for Meningioma Proliferation Cell Rep 2018 ORF Clones RC208947
CTNNB1 MicroRNA-452 promotes stem-like cells of hepatocellular carcinoma by inhibiting Sox7 involving Wnt/ß-catenin signaling pathway Oncotarget 2016 ORF Clones RC208947
CTNNB1 The ß-catenin E3 ubiquitin ligase SIAH-1 is regulated by CSN5/JAB1 in CRC cells Cell. Signal. May 2014 ORF Clones RC208947
CTNND1 Chromatin remodeling protein MORC2 promotes breast cancer invasion and metastasis through a PRD domain-mediated interaction with CTNND1 Oncotarget 2017 ORF Clones RG222771
CTNND1 Divergent roles of p120-catenin isoforms linked to altered cell viability, proliferation, and invasiveness in carcinogen-induced rat skin tumors Mol. Carcinog 2017 ORF Clones RC222771
CTNND1 P120ctn may participate in epithelial-mesenchymal transition in OSCC Indian J Cancer May 2016 ORF Clones RC222771
CTNND1 Identification of Phosphorylation Consensus Sequences and Endogenous Neuronal Substrates of the Psychiatric Risk Kinase TNIK J. Pharmacol. Exp. Ther. Dec 2015 ORF Clones RC222771
CTR9 PAF1 complex interactions with SETDB1 mediate promoter H3K9 methylation and transcriptional repression of Hoxa9 and Meis1 in acute myeloid leukemia Oncotarget 2018 ORF Clones RC208933
CTR9 Drosophila CG2469 Encodes a Homolog of Human CTR9 and Is Essential for Development G3 (Bethesda) 2016 ORF Clones RC208933
CTSA Susceptibility of microtubule-associated protein 1 light chain 3β (MAP1LC3B/ LC3B) knockout mice to lung injury and fibrosis FASEB J. 2019 ORF Clones MR207589
CTSA Proteomic Profiling of Cardiomyocyte-Specific Cathepsin A Overexpression Links Cathepsin A to the Oxidative Stress Response J. Proteome Res. 2016 ORF Clones RC213409
CTSB S-nitrosoglutathione Reductase Dysfunction Contributes to Obesity-Associated Hepatic Insulin Resistance via Regulating Autophagy Diabetes 2017 ORF Clones MG227342
CTSH Crystal structures of human procathepsin H PLoS ONE 2018 ORF Clones RC200373
CTSK PACMANS: A Bioinformatically Informed Algorithm to Predict, Design, and Disrupt Protease-on-Protease Hydrolysis Protein Sci 2017 ORF Clones RC204892
CTSO SNPs near the cysteine proteinase cathepsin O gene (CTSO) determine tamoxifen sensitivity in ERα-positive breast cancer through regulation of BRCA1 PLoS Genet. 2017 ORF Clones RC208268
CTSO Breast cancer chemoprevention pharmacogenomics: Deep sequencing and functional genomics of the ZNF423 and CTSO genes NPJ Breast Cancer 2017 ORF Clones SC119312
CTSZ Deguelin attenuates non-small cell lung cancer cell metastasis through inhibiting the CtsZ/FAK signaling pathway Cell. Signal. 2018 ORF Clones RC208341
CTTN Inhibitory cortactin nanobodies delineate the role of NTA- and SH3-domain-specific functions during invadopodium formation and cancer cell invasion FASEB J 2017 ORF Clones RC223259
CTTN Pro-invasive effect of proto-oncogene PBF is modulated by an interaction with cortactin J. Clin. Endocrinol. Metab. 2016 ORF Clones RC223259
CTTN PDCD10 (CCM3) regulates brain endothelial barrier integrity in cerebral cavernous malformation type 3: role of CCM3-ERK1/2-cortactin cross-talk Acta Neuropathol. Sep 2015 ORF Clones RC223259
CTTN Fascin actin bundling controls podosome turnover and disassembly while cortactin is involved in podosome assembly by its SH3 domain in THP-1 macrophages and dendritic cells Biochim. Biophys. Acta Jan 2015 ORF Clones RC223259
CTTN Podocalyxin-like 1 Promotes Invadopodia Formation and Metastasis through Activation of Rac1/Cdc42/Cortactin Signaling in Breast Cancer Cells Carcinogenesis Jun 2014 ORF Clones RC201111
CTXN3 A genome-wide association meta-analysis of plasma Aβ peptides concentrations in the elderly Mol. Psychiatry, Feb 2014. ORF Clones RC215242
CUL4B Proteomic analysis of the Cullin4B interactome using proximity-dependent biotinylation in living cells Proteomics 2017 ORF Clones RC206935
custom APOA1 Caveolin-1 interacts with ATP binding cassette transporter G1 (ABCG1) and regulates ABCG1-mediated cholesterol efflux Biochim. Biophys. Acta, Feb 2014. ORF Clones
CUX1 Transcription Factors with Conserved Binding Sites Near ATOH1 on the POU4F3 Gene Enhance the Induction of Cochlear Hair Cells Mol. Neurobiol. July 2014 ORF Clones RG221942
CWC27 Proline isomerisation as a novel regulatory mechanism for p38MAPK activation and functions Cell Death Differ. May 2016 ORF Clones RC223566
Cx26 Mechanism of gating by calcium in connexin hemichannels Proc. Natl. Acad. Sci. U.S.A. 2016 ORF Clones RC202092
CXCL1 Monoclonal Antibody against CXCL1 (HL2401) as a Novel Agent in Suppressing IL6 Expression and Tumoral Growth Theranostics 2019 ORF Clones RC201992
CXCL10 Pathogen evasion of chemokine response through suppression of CXCL10 bioRxiv 2019 ORF Clones RC203141
CXCL10 Pathogen-encoded evasion of CXCL10 and T cell responses bioRxiv 2019 ORF Clones RC203141
CXCL10 Mixed Lineage Kinase 3 Mediates Release of C-X-C Motif Ligand 10-Bearing Chemotactic Extracellular Vesicles from Lipotoxic Hepatocytes Hepatology Sep 2015 ORF Clones RG203141
CXCL14 A Crucial Role of CXCL14 for Promoting Regulatory T Cells Activation in Stroke Theranostics 2017 ORF Clones RC202533
CXCL5 Endothelial CXCL5 negatively regulates myelination and repair after white matter stroke bioRxiv 2019 ORF Clones MR200761
CXCL8 Serine hydroxymethyl transferase 1 stimulates pro-oncogenic cytokine expression through sialic acid to promote ovarian cancer tumor growth and progression Oncogene 2017 ORF Clones RC202075
CXCR1 CXC Receptor-1 Silencing Inhibits Androgen-Independent Prostate Cancer Cancer Res., Nov 2009; 69: 8265 - 8274 ORF Clones RC218227
CXCR3 CXCR3 Signaling in BRAFWT Melanoma Increases IL-8 Expression and Tumorigenicity PLoS ONE Mar 2015 ORF Clones RC206596
CXCR4 CXCL12 loaded-dermal filler captures CXCR4 expressing melanoma circulating tumor cells Cell Death Dis 2019 ORF Clones RG214548
CXCR4 Epigenetic regulation of CXCL12 plays a critical role in mediating tumor progression and the immune response in osteosarcoma Cancer Res. 2018 ORF Clones RC202069
CXCR4 Myeloid conditioning with c-kit-targeted CAR-T cells enables donor stem cell engraftment Molecular Therapy 2018 ORF Clones MR205485
CXCR4 C-X-C motif chemokine receptor 4 promotes tumor angiogenesis in gastric cancer via activation of JAK2/STAT3 Cell Biol. Int. 2017 ORF Clones RC214548
CXCR4 Missing-in-metastasis protein downregulates CXCR4 by promoting ubiquitination and interaction with small Rab GTPases J. Cell. Sci 2017 ORF Clones RC202069
CXCR4 Exploring the N-Terminal Region of C-X-C Motif Chemokine 12 (CXCL12): Identification of Plasma-Stable Cyclic Peptides As Novel, Potent C-X-C Chemokine Receptor Type 4 (CXCR4) Antagonists. J. Med. Chem. 2016 ORF Clones RG214548
CXCR4 Tubeimoside-1 suppresses breast cancer metastasis through downregulation of CXCR4 chemokine receptor expression BMB Rep 2016 ORF Clones RC202069
CXCR4 CXC Chemokine Receptor 4 Is a Cell Surface Receptor for Extracellular Ubiquitin J. Biol. Chem., May 2010; 285: 15566 - 15576 ORF Clones RC202069
CXCR5 CXCL13-CXCR5 co-expression regulates epithelial to mesenchymal transition of breast cancer cells during lymph node metastasis Breast Cancer Res. Treat. Dec 2013. ORF Clones RC213050
CXCR6 The Chemokine Receptor CXCR6 Evokes Reverse Signaling via the Transmembrane Chemokine CXCL16 Int J Mol Sci 2017 ORF Clones RG206517
CXCR6 Inverse signaling of the transmembrane chemokine CXCL16 contributes to proliferative and anti-apoptotic effects in cultured human meningioma cells Cell Commun. Signal 2016 ORF Clones RC206517
CXCR7 Beta-Arrestin-2 Counters CXCR7-mediated EGFR Transactivation and Proliferation Mol. Cancer Res. Feb 2016 ORF Clones RC206092
CXorf40A EOLA1 protects lipopolysaccharide induced IL-6 production and apoptosis by regulation of MT2A in human umbilical vein endothelial cells Mol. Cell. Biochem. Jun 2014 ORF Clones RC221372
CYB5A Dissociation Constants of Cytochrome P450 2C9 / Cytochrome P450 Reductase Complexes in a Lipid Bilayer Membrane Depend on NADPH: A Single Protein Tracking Study J. Am. Chem. Soc.2017 ORF Clones RC202378
CYLD IKK regulates the deubiquitinase CYLD at the postsynaptic density Biochem. Biophys. Res. Commun. Jun 2014 ORF Clones RC204099
CYP11B1 A high rate of novel CYP11B1 mutations in Saudi Arabia J. Steroid Biochem. Mol. Biol. 2017 ORF Clones RC216551
CYP17A1 CYP17A1 Maintains the Survival of Glioblastomas by Regulating SAR1-Mediated Endoplasmic Reticulum Health and Redox Homeostasis Cancers (Basel) 2019 ORF Clones MR208156
CYP19A1 The Protective Effect of Aromatase on NSC-34 Cells with Stably Expressed hSOD1-G93A Neuroscience 2019 ORF Clones MR224509
CYP19A1 Brain-synthesized estrogens regulate cortical migration in a sexually divergent manner BioRxiv 2019 ORF Clones MR224509
CYP19A1 Increased adipose tissue aromatase activity improves insulin sensitivity and reduces adipose tissue inflammation in male mice Am. J. Physiol. Endocrinol. Metab. 2017 ORF Clones SC127848
CYP19A1 Acquired CYP19A1 amplification is an early specific mechanism of aromatase inhibitor resistance in ERα metastatic breast cancer Nat. Genet. 2017 ORF Clones RC205890
CYP1A1 Similarities in mRNA expression of peripheral blood drug metabolizing enzymes and cancer marker genes with biopsy samples of head and neck cancer patients Biomarkers 2019 ORF Clones RC205760
CYP1B1 Similarities in mRNA expression of peripheral blood drug metabolizing enzymes and cancer marker genes with biopsy samples of head and neck cancer patients Biomarkers 2019 ORF Clones RC204074
CYP1B1 Cytochrome P450 1B1 inhibition suppresses tumorigenicity of prostate cancer via caspase-1 activation Oncotarget 2017 ORF Clones RC204074
CYP1B1 Development of an In Vitro Model to Screen CYP1B1-Targeted Anticancer Prodrugs Journal of Biomolecular Screening 2016 ORF Clones RC204074
CYP1B1 Loss of miR-200c up-regulates CYP1B1 and confers docetaxel resistance in renal cell carcinoma Oncotarget Apr 2015 ORF Clones RC204074
CYP24A1 CYP24A1-induced vitamin D insufficiency promotes breast cancer growth Oncol. Rep. 2016 ORF Clones RC213246
CYP24A1 Impact of CYP24A1 overexpression on growth of colorectal tumour xenografts in mice fed with vitamin D and soy Int. J. Cancer Aug 2015 ORF Clones RG213246
CYP26A1 Retinoic acid‑metabolizing enzyme cytochrome P450 26A1 promotes skin carcinogenesis induced by 7,12‑dimethylbenz[a]anthracene Oncol Lett 2018 ORF Clones RG216278
Cyp26a1 Hedgehog and retinoid signaling alters multiple myeloma microenvironment and generates bortezomib resistance J. Clin. Invest. 2016 ORF Clones RC216278
CYP27A1 Genetic obesity increases pancreatic expression of mitochondrial proteins which regulate cholesterol efflux in BRIN-BD11 insulinoma cells Biosci. Rep. 2019 ORF Clones RC222953
CYP2A13 ?-H2AX is a sensitive marker of DNA damage induced by metabolically activated 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone Toxicol In Vitro Oct 2015 ORF Clones RC214289
CYP2A6 Similarities in mRNA expression of peripheral blood drug metabolizing enzymes and cancer marker genes with biopsy samples of head and neck cancer patients Biomarkers 2019 ORF Clones RC222995
CYP2C19 MicroRNA hsa-miR-29a-3p modulates CYP2C19 in human liver cells Biochem. Pharmacol. Aug 2015 ORF Clones RC211377
CYP2C8 CYP2C8-derived epoxyeicosatrienoic acids decrease oxidative stress-induced endothelial apoptosis in development of atherosclerosis: Role of Nrf2 activation J. Huazhong Univ. Sci. Technol. Med. Sci. Nov 2015 ORF Clones RC204605
CYP2C8 A potential therapeutic effect of CYP2C8 overexpression on anti-TNF-a activity Int. J. Mol. Med. Sep 2014 ORF Clones RG204605
CYP2C8 Targeting of Splice Variants of Human Cytochrome P450 2C8 (CYP2C8) to Mitochondria and Their Role in Arachidonic Acid Metabolism and Respiratory Dysfunction J. Biol. Chem. Aug 2014 ORF Clones RG204605
CYP2C9 Cytochrome P450 2C Epoxygenases Mediate Photochemical Stress-induced Death of Photoreceptors J. Biol. Chem., Feb 2014. ORF Clones RG220997
CYP2E Similarities in mRNA expression of peripheral blood drug metabolizing enzymes and cancer marker genes with biopsy samples of head and neck cancer patients Biomarkers 2019 ORF Clones RC213502
CYP2J2 Activation of the pro-migratory bone morphogenetic protein receptor 1B gene in human MDA-MB-468 triple-negative breast cancer cells that over-express CYP2J2 Int. J. Biochem. Cell Biol. 2016 ORF Clones RC207417
CYP2J2 Early Changes in Cytochrome P450s and Their Associated Arachidonic Acid Metabolites Play a Crucial Role in the Initiation of Cardiac Hypertrophy Induced by Isoproterenol. Drug Metab. Dispos. 2015 ORF Clones RC207417
CYP2J6 Targeting CYP2J to reduce paclitaxel-induced peripheral neuropathic pain Proc. Natl. Acad. Sci. U.S.A. 2016 ORF Clones MG208057
Cyp3a11 Targeting CYP2J to reduce paclitaxel-induced peripheral neuropathic pain Proc. Natl. Acad. Sci. U.S.A. 2016 ORF Clones MG208124
CYP3A5 CYP3A5 mediates bioactivation and cytotoxicity of tetrandrine Arch. Toxicol. Aug 2015 ORF Clones RC207432
CYP450OR NAD(P)H-dependent Quinone Oxidoreductase 1 (NQO1) and Cytochrome P450 Oxidoreductase (CYP450OR) differentially regulate menadione-mediated alterations in redox status, survival and metabolism in pancreatic ß-cells Toxicol. Lett. 2016 ORF Clones RC202172
Cyp4a10 Cytotoxic 1-Deoxysphingolipids Are Metabolized by a Cytochrome P450-Dependent Pathway J. Lipid Res. 2016 ORF Clones MR208179
CYP4B1 Suppression of cytochrome P450 4B1: An early event in adrenocortical tumorigenesis Surgery 2016 ORF Clones RC204606
CYP4F11 Functional characterization of a common CYP4F11 genetic variant and identification of functionally defective CYP4F11 variants in erythromycin metabolism and 20-HETE synthesis Arch. Biochem. Biophys 2017 ORF Clones RC203705
Cyp4f13 Cytotoxic 1-Deoxysphingolipids Are Metabolized by a Cytochrome P450-Dependent Pathway J. Lipid Res. 2016 ORF Clones MR208371
CYP8B1 Therapeutic modulation of the bile acid pool by Cyp8b1 knockdown protects against nonalcoholic fatty liver disease in mice FASEB J. 2018 ORF Clones MR208021
CypB Cyclophilin B enhances HIV-1 infection Virology 2016 ORF Clones RC203180
CYR61 Overexpression of CCN1 in Het1A cells attenuates bile-induced esophageal metaplasia through suppressing non-canonical NFκB activation Cytokine 2019 ORF Clones RC203492
CYR61 Extracellular Matrix Protein CCN1 (Cyr61) Negatively Regulates Endothelial Cell Adhesion Molecules Thesis Jun 2015 ORF Clones RC203492
CYSLTR1 Inflammatory Eicosanoids Increase Amyloid Precursor Protein Expression via Activation of Multiple Neuronal Receptors Sci Rep Dec 2015 ORF Clones RC207763
cystatin C Differential cathepsin responses to inhibitor-induced feedback: E-64 and cystatin C elevate active cathepsin S and suppress active cathepsin L in breast cancer cells Int. J. Biochem. Cell Biol. 2016 ORF Clones RC210730
DAAM1 A global transcriptional network connecting noncoding mutations to changes in tumor gene expression Nat. Genet. 2018 ORF Clones RC217675
DAAM1 LRP6 exerts non-canonical effects on Wnt signaling during neural tube closure Hum. Mol. Genet., Aug 2013; 10.1093/hmg/ddt277. ORF Clones RC217675
DAB1 A Pentanucleotide ATTTC Repeat Insertion in the Non-coding Region of DAB1, Mapping to SCA37, Causes Spinocerebellar Ataxia. Am. J. Hum. Genet. 2017 ORF Clones RC214664
DAB2 Low disabled-2 expression promotes tumor progression and determines poor survival and high recurrence of esophageal squamous cell carcinoma Oncotarget 2016 ORF Clones RG200481
DACH1 Effect of DACH1 on proliferation and invasion of laryngeal squamous cell carcinoma Head Face Med 2018 ORF Clones RC221505
DACH1 The transcription factor Dach1 is essential for podocyte function J. Cell. Mol. Med. 2018 ORF Clones MG216327
DACH1 DACH1 stimulates shear stress-guided endothelial cell migration and coronary artery growth through the CXCL12-CXCR4 signaling axis. Genes Dev. 2017 ORF Clones MG216327
DACT3 Dact3 inhibits the malignant phenotype of non-small cell lung cancer through downregulation of c-Myb Int J Clin Exp Pathol 2017 ORF Clones RC229315
DAG1 Conformational regulation of proteolysis in the extracellular matrix receptor dystroglycan bioRxiv 2018 ORF Clones RC201121
DAG1 Posttranslational removal of a-dystroglycan N terminus by PC5/6 cleavage is important for uterine preparation for embryo implantation in women FASEB J. Jun 2015 ORF Clones RC201121
DAGLB Oxyradical Stress Increases the Biosynthesis of 2-Arachidonoylglycerol: Involvement of NADPH Oxidase Am. J. Physiol., Cell Physiol. 2016 ORF Clones RC226682
DAOA Identification of the Mitochondrial MSRB2 as a Binding Partner of LG72 Cell. Mol. Neurobiol. July 2014 ORF Clones RC212162
DAPK3 Activation of AKT negatively regulates the pro-apoptotic function of death-associated protein kinase 3 (DAPK3) in prostate cancer Cancer Lett. Jul 2016 ORF Clones RC213427
DAXX DAXX Suppresses Tumor-Initiating Cells in Estrogen Receptor-positive Breast Cancer following endocrine therapy Cancer Res. 2019 ORF Clones RC226603
DAZAP1 Specific autoantigens identified by sera obtained from mice that are immunized with testicular germ cells alone Sci Rep 2016 ORF Clones MR215857
DAZL Phosphorylation of the RNA-binding protein Dazl by MAPKAP kinase 2 regulates spermatogenesis Mol. Biol. Cell 2016 ORF Clones RC231158
DBH Characterization of SNPs in the dopamine-β-hydroxylase gene providing new insights into its structure-function relationship Neurogenetics 2017 ORF Clones RC212355
DBP Vitamin D-Binding Protein Enhances Epithelial Ovarian Cancer Progression by Regulating the Insulin-like Growth Factor-1/Akt Pathway and Vitamin D Receptor Transcription Clin. Cancer Res. 2018 ORF Clones RG202051
DCBLD1 Dynamic multi-site phosphorylation by Fyn and Abl drives the interaction between CRKL and the novel scaffolding receptors DCBLD1 and DCBLD2 Biochem. J. 2017 ORF Clones MR206887
DCBLD2 Dynamic multi-site phosphorylation by Fyn and Abl drives the interaction between CRKL and the novel scaffolding receptors DCBLD1 and DCBLD2 Biochem. J. 2017 ORF Clones RC224483
DCLK1 Application of RNA-sequencing to identify transcriptome modification by DCLK1 in colorectal cancer cells Cancer Gene Ther. 2019 ORF Clones RG217050
DCLK1 Doublecotin-like kinase 1 increases chemoresistance of colorectal cancer cells through the anti-apoptosis pathway bioRxiv 2019 ORF Clones RG217050
DCLK1 Pancreatic Neuroendocrine Tumors and EMT Behavior are Driven by the CSC Marker DCLK1 Mol. Cancer Res 2017 ORF Clones RC217050
DCLK1 Small molecule kinase inhibitor LRRK2-IN-1 demonstrates potent activity against colorectal and pancreatic cancer through inhibition of doublecortin-like kinase 1 Mol. Cancer Jun 2014 ORF Clones RG217050
DCLRE1B Telomerase promotes formation of a telomere protective complex in cancer cells Sci Adv 2019 ORF Clones RC205744
DCNL1 DCNL1 Functions as a Substrate Sensor and Activator of Cullin 2-RING Ligase Mol. Cell. Biol., Apr 2013; 33: 1621 - 1631. ORF Clones RC203427
DCNL2 DCNL1 Functions as a Substrate Sensor and Activator of Cullin 2-RING Ligase Mol. Cell. Biol., Apr 2013; 33: 1621 - 1631. ORF Clones RC208865
DCNL3 DCNL1 Functions as a Substrate Sensor and Activator of Cullin 2-RING Ligase Mol. Cell. Biol., Apr 2013; 33: 1621 - 1631. ORF Clones RC208082
DCP1A Decapping protein 1 phosphorylation modulates IL-8 expression during respiratory syncytial virus infection Virology Mar 2015 ORF Clones RC201330
DCUN1D5 The E3 ubiquitin ligase RNF114 and TAB1 degradation are required for maternal-to-zygotic transition EMBO Rep 2017 ORF Clones MR202903
DCX Stage-Specific Modulation of Cortical Neuronal Development by Mmu-miR-134 Cereb Cortex, Aug 2011; 21: 1857 - 1869. ORF Clones MR205614
DDAH2 Determine exogenous human DDAH2 gene function in rabbit bone marrow-derived endothelial progenitor cells in vitro Cell Biochem. Funct 2017 ORF Clones RG200287
DDHD1 The phospholipase DDHD1 as a new target in colorectal cancer therapy J. Exp. Clin. Cancer Res. 2018 ORF Clones RC205548
DDIAS DDIAS promotes invasion and proliferation of non-small cell lung cancer and predicts poor survival of lung cancer patients Int J Clin Exp Pathol 2014 ORF Clones RC206347
DDIT3 Endoplasmic Reticulum Stress Increases DUSP5 Expression via PERK-CHOP Pathway, Leading to Hepatocyte Death Int J Mol Sci 2019 ORF Clones MR201400
DDIT3 miR-1271 inhibits ERα expression and confers letrozole resistance in breast cancer Oncotarget 2017 ORF Clones RC231040
DDIT3 Differential expression of endoplasmic reticulum stress-response proteins in different renal tubule subtypes of OVE26 diabetic mice Cell Stress Chaperones Oct 2015 ORF Clones RC231040
DDIT3 Is there a common upstream link for autophagic and apoptotic cell death in human high-grade gliomas? Neuro Oncology, Jul 2011; 13: 725 - 735. ORF Clones RC201301
DDIT4 APOBEC3G-regulated host factors interfere with measles virus replication: role of REDD1 and mTORC1 inhibition J. Virol. 2018 ORF Clones RC202847
DDR1 DDR1 regulates thyroid cancer cell differentiation via IGF-2/IR-A autocrine signaling loop Endocr. Relat. Cancer 2018 ORF Clones RG201224
DDR1 Discoidin domain receptor 1 modulates insulin receptor signaling and biological responses in breast cancer cells Oncotarget 2017 ORF Clones RC201224
DDR1 Novel cross talk between IGF-IR and DDR1 regulates IGF-IR trafficking, signaling and biological responses Oncotarget Mar 2015 ORF Clones RC201224
DDR2 Clustering, Spatial Distribution and Phosphorylation of Discoidin Domain Receptors 1 and 2 in Response to Soluble Collagen Type I J. Mol. Biol. 2018 ORF Clones RG208745
DDR2 Characterization of DDR2 inhibitors for the treatment of DDR2 mutated non-small cell lung cancer ACS chemical biology Sep 2015 ORF Clones RC208745
DDX17 Regulation of miRNA biogenesis and histone modification by K63-polyubiquitinated DDX17 controls cancer stem-like features Cancer Res. 2019 ORF Clones RC200599
DDX27 Expression of DDX27 contributes to colony-forming ability of gastric cancer cells and correlates with poor prognosis in gastric cancer Am J Cancer Res Dec 2015 ORF Clones RC219725
DDX39B Nuclear Export of Human Hepatitis B Virus Core Protein and Pregenomic RNA Depends on the Cellular NXF1-p15 Machinery PLoS ONE Nov 2014 ORF Clones RC201248
DDX3X Targetome analysis of chaperone-mediated autophagy in cancer cells Autophagy 2019 ORF Clones RC204171
DDX3X Rottlerin upregulates DDX3 expression in hepatocellular carcinoma Biochem. Biophys. Res. Commun. 2017 ORF Clones RC204171
DDX3X Ezrin binds to DEAD-box RNA helicase DDX3 and regulates its function and protein level Mol. Cell. Biol. Jul 2015 ORF Clones RC204171
DDX3X DDX3X Induces Primary EGFR-TKI Resistance Based on Intratumor Heterogeneity in Lung Cancer Cells Harboring EGFR-Activating Mutations PLoS ONE Oct 2014 ORF Clones RC204171
DDX41 The DEAD-Box RNA Helicase DDX41 is a Novel Repressor of p21(WAF1/CIP1) Translation J. Biol. Chem 2017 ORF Clones RC201898
DDX47 C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles Cell 2016 ORF Clones RG209448
DDX5 Endogenous interaction profiling identifies DDX5 as an oncogenic coactivator of transcription factor Fra-1 Oncogene 2019 ORF Clones RC200371
DDX5 RNA helicase DDX5 participates in oxLDL-induced macrophage scavenger receptor 1 expression by suppressing mRNA degradation Exp. Cell Res. 2018 ORF Clones RC200371
DDX5 Identifizierung neuer Coregulatoren von SOX9 und RUNX2 in chondrogenen Progenitorzellen in der Osteoarthrose Thesis Jun 2015 ORF Clones RC200371
DDX58 A GTPase-activating protein binding protein (G3BP1) / antiviral protein relay conveys arteriosclerotic Wnt signals in aortic smooth muscle cells J. Biol. Chem. 2018 ORF Clones RC217615
DDX58 RIG-I expression in perifascicular myofibers is a reliable biomarker of dermatomyositis Arthritis Res. Ther. 2017 ORF Clones RC217615
DDX6 Phosphorothioate Antisense Oligonucleotides Bind P-Body Proteins and Mediate P-Body Assembly Nucleic Acid Ther 2019 ORF Clones RG209431
DECR2 Experimental validation of predicted subcellular localizations of human proteins BMC Res Notes Dec 2014 ORF Clones RG203715
DEFB131 Expression of Beta-Defensin 131 Promotes an Innate Immune Response in Human Prostate Epithelial Cells PLoS ONE Dec 2015 ORF Clones RC218014
DEFB4A IL-1ß-Induced Protection of Keratinocytes against Staphylococcus aureus-Secreted Proteases Is Mediated by Human ß-Defensin 2 J. Invest. Dermatol 2017 ORF Clones RC219487
DEFB4A IL-1beInduced Protection of Keratinocytes JID Open 2016 ORF Clones RC219487
DEK DEK Depletion Negatively Regulates Rho/ROCK/MLC Pathway in Non–Small Cell Lung Cancer Journal of Histochemistry & Cytochemistry, May 2013; 10.1369/0022155413488120. ORF Clones RC205754
DENR Doxorubicin-induced cardiomyocyte death is mediated by unchecked mitochondrial fission and mitophagy FASEB J. 2019 ORF Clones RC203227
DENR The Fine Tuning of Drp1-Dependent Mitochondrial Remodeling and Autophagy Controls Neuronal Differentiation Front Cell Neurosci 2019 ORF Clones RC203227
DEXI DEXI, a candidate gene for type 1 diabetes, modulates rat and human pancreatic beta cell inflammation via regulation of the type I IFN/STAT signalling pathway Diabetologia 2018 ORF Clones RC207463
DGAT1 Discovery and optimization of adamantane carboxylic acid derivatives as potent diacylglycerol acyltransferase 1 inhibitors for the potential treatment of obesity and diabetes Eur J Med Chem Jun 2015 ORF Clones RC220595
DGAT1 Synthesis and Diacylglycerol Acyltransferase-1 Inhibition of Azabicyclo [3.1. 0] hexane Derivatives BULLETIN OF THEKOREAN CHEMICAL SOCIETY Jun 2015 ORF Clones RC220595
DGAT2 Mouse lipogenic proteins promote the co-accumulation of triacylglycerols and sesquiterpenes in plant cells Planta 2019 ORF Clones MR218673
Dgat2 Host triacylglycerols shape the lipidome of intracellular trypanosomes and modulate their growth PLoS Pathog. 2017 ORF Clones MR218673
DGAT2 Chlamydia trachomatis regulates growth and development in response to host cell fatty acid availability in the absence of lipid droplets Cell. Microbiol.2017 ORF Clones MG218673
DGLUCY C14orf159 suppresses gastric cancer cells' invasion and proliferation by inactivating ERK signaling Cancer Manag Res 2019 ORF Clones RC223847
DHFR DHFR/TYMS are positive regulators of glioma cell growth and modulate chemo-sensitivity to temozolomide Eur. J. Pharmacol. 2019 ORF Clones RC200089
DHFR NADPH production by the oxidative pentose-phosphate pathway supports folate metabolism Nat Metab 2019 ORF Clones RC200089
DHFRL1 Identification of a de novo thymidylate biosynthesis pathway in mammalian mitochondria PNAS, Sep 2011; 108: 15163 - 15168. ORF Clones RC208452
DHH Functional analysis of novel desert hedgehog gene variants improves the clinical interpretation of genomic data and provides a more accurate diagnosis for patients with 46,XY differences of sex development J. Med. Genet. 2019 ORF Clones RC206715
DHH Hypoxia Triggers Hedgehog-Mediated Tumor–Stromal Interactions in Pancreatic Cancer Cancer Res., Jun 2013; 73: 3235 - 3247. ORF Clones RC206715
DHPS Inhibition of Deoxyhypusine Synthase Enhances Islet ß Cell Function and Survival in the Setting of Endoplasmic Reticulum Stress and Type 2 Diabetes J. Biol. Chem., Dec 2010; 285: 39943 - 39952 ORF Clones RC204235
DHRS9 Inhibition of dihydrotestosterone synthesis in prostate cancer by combined frontdoor and backdoor pathway blockade Oncotarget 2018 ORF Clones RC220853
DHX15 DHX15 Is a Coreceptor for RLR Signaling That Promotes Antiviral Defense Against RNA Virus Infection J. Interferon Cytokine Res. 2019 ORF Clones RC205914
DHX15 The genomic landscape of core-binding factor acute myeloid leukemias Nat. Genet. 2016 ORF Clones RC205914
Dhx15 DHX15 Senses Double-Stranded RNA in Myeloid Dendritic Cells J. Immunol. Aug 2014 ORF Clones MR226475
DHX30 De Novo Missense Mutations in DHX30 Impair Global Translation and Cause a Neurodevelopmental Disorder. Am. J. Hum. Genet.2017 ORF Clones RC204467
DHX58 Quantitative Micro-Spectroscopic Imaging Reveals Viral and Cellular RNA Helicase Interactions in Live Cells J. Biol. Chem. 2017 ORF Clones RC204837
diap2 Remodeling of the Inner Hair Cell Microtubule Meshwork in a Mouse Model of Auditory Neuropathy AUNA1 eNeuro 2016 ORF Clones MG226708
DIAPH1 EGF hijacks miR-198/FSTL1 wound-healing switch and steers a two-pronged pathway toward metastasis J. Exp. Med. 2017 ORF Clones RC216318
DIP2C Loss of DIP2C in RKO cells stimulates changes in DNA methylation and epithelial-mesenchymal transition BMC Cancer 2017 ORF Clones RC209325
DIRAS3 The expression of aplysia ras homolog I (ARHI) and its inhibitory effect on cell biological behavior in esophageal squamous cell carcinoma Onco Targets Ther 2017 ORF Clones RG202787
DIRAS3 Distinct subgroup of the Ras family member 3 (DIRAS3) expression impairs metastasis and induces autophagy of gastric cancer cells in mice J. Cancer Res. Clin. Oncol. 2018 ORF Clones RG202787
DISC1 Neurexin-Neuroligin Synaptic Complex Regulates Schizophrenia-Related DISC1/Kal-7/Rac1 Signalosome Neural Plast. Jun 2015 ORF Clones MR226643
DISC1 Neurexin-Neuroligin Synaptic Complex Regulates Schizophrenia-Related DISC1/Kal-7/Rac1 “Signalosome” Neural Plasticity May 2015 ORF Clones MR226643
DKC1 The C-terminal extension of human telomerase reverse transcriptase is necessary for high affinity binding to telomeric DNA Biochimie 2016 ORF Clones RC201455
DKK1 Activation of the Wnt Pathway by Small Peptides: Rational Design, Synthesis and Biological Evaluation ChemMedChem 2017 ORF Clones RC200094
DKK1 Bone Morphogenetic Protein Signaling Suppresses Wound-Induced Skin Repair by Inhibiting Keratinocyte Proliferation and Migration J. Invest. Dermatol. Nov 2013 ORF Clones RC200094
DKK2 The posterior HOXD locus: Its contribution to phenotype and malignancy of Ewing sarcoma Oncotarget 2016 ORF Clones RC224432
DKK2 Epigenetic silencing of DKK2 and Wnt signal pathway components in human ovarian carcinoma Carcinogenesis, Oct 2012; 10.1093/carcin/bgs278. ORF Clones RC224432
DKK2 Salinomycin inhibits Wnt signaling and selectively induces apoptosis in chronic lymphocytic leukemia cells PNAS, Aug 2011; 108: 13253 - 13257. ORF Clones RC224432
DKK3 A novel FOXO1-mediated dedifferentiation blocking role for DKK3 in adrenocortical carcinogenesis BMC Cancer 2017 ORF Clones RC221022
DKK4 DKK4-knockdown enhances chemosensitivity of A549/DTX cells to docetaxel Acta Biochimica et Biophysica Sinica 2017 ORF Clones RC221217
DLD Rearrangement of Mitochondrial Pyruvate Dehydrogenase Subunit Dihydrolipoamide Dehydrogenase Protein-Protein Interactions by the MDM2 Ligand Nutlin-3 Proteomics Jun 2016 ORF Clones RG200639
DLD Stimulation of reactive oxygen species generation by disease-causing mutations of lipoamide dehydrogenase Hum. Mol. Genet., Aug 2011; 20: 2984 - 2995. ORF Clones RC200639
DLG2 Dlg1 activates beta-catenin signaling to regulate retinal angiogenesis and the blood-retina and blood-brain barriers Elife 2019 ORF Clones MR222602
DLK1 Imprinting defects at human 14q32 locus alters gene expression and is associated with the pathobiology of osteosarcoma Oncotarget 2016 ORF Clones RC202923
DLL3 DLL3 regulates the migration and invasion of small cell lung cancer by modulating Snail Cancer Sci. 2019 ORF Clones RC200005
DLX1 DLX1 acts as a crucial target of FOXM1 to promote ovarian cancer aggressiveness by enhancing TGF-ß/SMAD4 signaling Oncogene 2016 ORF Clones RC206895
DLX2 Wnt5a Is a Transcriptional Target of Dlx Homeogenes and Promotes Differentiation of Interneuron Progenitors In Vitro and In Vivo J. Neurosci., Feb 2011; 31: 2675 - 2687 ORF Clones RC207545
DLX3 Anthropoid primate-specific retroviral element THE1B controls expression of CRH in placenta and alters gestation length PLoS Biol. 2018 ORF Clones RC205795
DLX5 DLX5, FGF8 and the Pin1 isomerase control ?Np63a protein stability during limb development: a regulatory loop at the basis of the SHFM and EEC congenital malformations Hum. Mol. Genet. Mar 2014 ORF Clones RC202525
DLX5 Wnt5a Is a Transcriptional Target of Dlx Homeogenes and Promotes Differentiation of Interneuron Progenitors In Vitro and In Vivo J. Neurosci., Feb 2011; 31: 2675 - 2687 ORF Clones RC202525
DNA2 Genomic analysis of primordial dwarfism reveals novel disease genes Genome Res., Feb 2014. ORF Clones RC217395
DNAAF1 Mutations in the Motile Cilia Gene DNAAF1 Are Associated with Neural Tube Defects in Humans G3 (Bethesda) 2016 ORF Clones RG205452
Dnaaf5 ZMYND10 functions in a chaperone relay during axonemal dynein assembly bioRxiv 2017 ORF Clones MG221395
DNAJB1 Human Heat shock protein 40 (Hsp40/DnaJB1) promotes influenza A virus replication by assisting nuclear import of viral ribonucleoproteins Sci Rep Jan 2016 ORF Clones RG201762
DNAJB11 Erdj3 has an essential role for Z variant Alpha-1-Antitrypsin Degradation. J. Cell. Biochem. 2017 ORF Clones RG200216
DNAJB3 DNAJB3 attenuates metabolic stress and promotes glucose uptake by eliciting Glut4 translocation Sci Rep 2019 ORF Clones RC205526
DNAJC15 ETV7-Mediated DNAJC15 Repression Leads to Doxorubicin Resistance in Breast Cancer Cells Neoplasia 2018 ORF Clones RC210567
DNAJC5 DnaJ/Hsc70 chaperone complexes control the extracellular release of neurodegenerative-associated proteins EMBO J. 2016 ORF Clones RR202869
DNAJC5B Heat shock proteins HSPB8 and DNAJC5B have HCV antiviral activity PLoS ONE 2017 ORF Clones RC205251
DNASE1 ?-H2AX induced by linear alkylbenzene sulfonates is due to deoxyribonuclease-1 translocation to the nucleus via actin disruption Mutat. Res. Apr 2015 ORF Clones RG205927
DNASE2 Type I interferon-mediated autoinflammation due to DNase II deficiency Nat Commun 2017 ORF Clones RC209573
DNASE2 Toll-like Receptor 9 Can be Activated by Endogenous Mitochondrial DNA to Induce Podocyte Apoptosis Sci Rep Mar 2016 ORF Clones RC209573
DNASE2B Genome-wide Identification of Chemosensitive Single Nucleotide Polymorphism Markers in Gastric Cancer Anticancer Res, Dec 2011; 31: 4329 - 4338. ORF Clones RC212192
DNM1L Determination of oligomerization state of Drp1 protein in living cells at nanomolar concentrations Sci Rep 2019 ORF Clones RG221708
DNM1L The causal role of mitochondrial dynamics in regulating insulin resistance in diabetes: link through mitochondrial reactive oxygen species Oxid Med Cell Longev. 2018 ORF Clones RG202046
DNM1L Insight into the fission mechanism by quantitative characterization of Drp1 protein distribution in the living cell Sci Rep 2018 ORF Clones RG221708
DNM1L FUNDC1 regulates mitochondrial dynamics at the ER-mitochondrial contact site under hypoxic conditions EMBO J. May 2016 ORF Clones RC202046
DNMT1 The repression and reciprocal interaction of DNA methyltransferase 1 and specificity protein 1 contributes to the inhibition of MET expression by the combination of Chinese herbal medicine FZKA decoction and erlotinib J Ethnopharmacol 2019 ORF Clones RG226414
DNMT1 Structural and mechanistic insights into UHRF1-mediated DNMT1 activation in the maintenance DNA methylation Nucleic Acids Res. 2018 ORF Clones RC226414
DNMT1 Magnetic immunoassay using CdSe/ZnS quantum dots as fluorescent probes to detect the level of DNA methyltransferase 1 in human serum sample Int J Nanomedicine 2018 ORF Clones RC226414
DNMT1 The enhancement of combination of berberine and metformin in inhibition of DNMT1 gene expression through interplay of SP1 and PDPK1 J. Cell. Mol. Med. 2017 ORF Clones RG217851
DNMT1 Interplay of DNA methyltransferase 1 and EZH2 through inactivation of Stat3 contributes to β-elemene-inhibited growth of nasopharyngeal carcinoma cells Sci Rep 2017 ORF Clones RC226414
Dnmt1 Targeting EP4 downstream c-Jun through ERK1/2-mediated reduction of DNMT1 reveals novel mechanism of solamargine-inhibited growth of lung cancer cells J. Cell. Mol. Med. 2016 ORF Clones MG212056
DNMT1 Inhibition of EZH2 via activation of SAPK/JNK and reduction of p65 and DNMT1 as a novel mechanism in inhibition of human lung cancer cells by polyphyllin I J. Exp. Clin. Cancer Res. 2016 ORF Clones RC226414
DNMT1 Activation of SAPK/JNK mediated the inhibition and reciprocal interaction of DNA methyltransferase 1 and EZH2 by ursolic acid in human lung cancer cells J. Exp. Clin. Cancer Res. Sep 2015 ORF Clones RC226414
DNMT1 Tcl1 protein functions as an inhibitor of de novo DNA methylation in B-cell chronic lymphocytic leukemia (CLL) PNAS, Feb 2012; 109: 2555 - 2560. ORF Clones RC217851
DNMT3A Nerve injury-induced epigenetic silencing of opioid receptors controlled by DNMT3a in primary afferent neurons Pain 2017 ORF Clones RR200036
DNMT3A Absence of genomic hypomethylation or regulation of cytosine-modifying enzymes with aging in male and female mice Epigenetics Chromatin 2016 ORF Clones RC208192
DNMT3A The R882H DNMT3A Mutation Associated with AML Dominantly Inhibits Wild-Type DNMT3A by Blocking Its Ability to Form Active Tetramers Cancer Cell Mar 2014 ORF Clones RC208192
DNMT3A Tcl1 protein functions as an inhibitor of de novo DNA methylation in B-cell chronic lymphocytic leukemia (CLL) PNAS, Feb 2012; 109: 2555 - 2560. ORF Clones RC208192
DNMT3B Tcl1 protein functions as an inhibitor of de novo DNA methylation in B-cell chronic lymphocytic leukemia (CLL) PNAS, Feb 2012; 109: 2555 - 2560. ORF Clones RC223206
DNMT3L Tcl1 protein functions as an inhibitor of de novo DNA methylation in B-cell chronic lymphocytic leukemia (CLL) PNAS, Feb 2012; 109: 2555 - 2560. ORF Clones RC200187
DNPEP Specific autoantigens identified by sera obtained from mice that are immunized with testicular germ cells alone Sci Rep 2016 ORF Clones MR207553
DNTTIP2 Characterization of nucleolar localization and exclusion signals in terminal deoxynucleotidyltransferase interacting factor 2/estrogen receptor α-binding protein Biosci. Biotechnol. Biochem. 2019 ORF Clones RC216436
DOC2B Doc2b Protects β-Cells Against Inflammatory Damage and Enhances Function Diabetes 2018 ORF Clones RC218949
DOC2B DNA Promoter Methylation Dependent Transcription of Double C2 Like Domain Beta (DOC2B) Gene Regulates Tumor Growth in Human Cervical Cancer J. Biol. Chem. Feb 2014 ORF Clones RC218949
DOCK8 Dedicator of cytokinesis 8 regulates signal transducer and activator of transcription 3 activation and promotes TH17 cell differentiation J. Allergy Clin. Immunol. 2016 ORF Clones RC222789
DPAGT1 DPAGT1-CDG: Functional analysis of disease-causing pathogenic mutations and role of endoplasmic reticulum stress PLoS ONE 2017 ORF Clones RG201787
DPP4 Dipeptidyl peptidase-4 plays a pathogenic role in BSA-induced kidney injury in diabetic mice Sci Rep 2019 ORF Clones RG209466
DPP4 Identification of residues controlling restriction versus enhancing activities of IFITM proteins on the entry of human coronaviruses J. Virol. 2017 ORF Clones RC209466
DPP4 Lipidation increases antiviral activities of coronavirus fusion-inhibiting peptides Virology 2017 ORF Clones RC209466
DPP4 The tetraspanin CD9 facilitates MERS-coronavirus entry by scaffolding host cell receptors and proteases PLoS Pathog. 2017 ORF Clones RC209466
DPP4 Proteolytic processing of Middle East respiratory syndrome coronavirus spikes expands virus tropism Proc. Natl. Acad. Sci. U.S.A. 2016 ORF Clones RC209466
DPP4 Interactions of DPP-4 and integrin ß1 influences endothelial-to-mesenchymal transition Kidney Int. Apr 2015 ORF Clones RG209466
DPP4 Corona and Influenza Virus Proteolytic Priming takes place in Tetraspanin-Enriched Membrane Microdomains J. Virol. Apr 2015 ORF Clones RC209466
DPP4 Receptor variation and susceptibility to MERS coronavirus infection J. Virol., Feb 2014. ORF Clones RC209466
DPP6 A nanobody-based tracer targeting DPP6 for non-invasive imaging of human pancreatic endocrine cells Sci Rep 2017 ORF Clones RC216919
DPP6 A nanobody-based tracer targeting DPP6 for non-invasive imaging of human pancreatic endocrine cells Sci Rep 2017 ORF Clones MR210746
DPP6 Use of whole exome sequencing for the identification of ito-based arrhythmia mechanism and therapy J Am Heart Assoc May 2015 ORF Clones RC214014
DPPA5 DPPA5 Supports Pluripotency and Reprogramming by Regulating NANOG Turnover Stem Cells Dec 2015 ORF Clones RC222509
DPYSL2 Inhibition of Ubc9-Induced CRMP2 SUMOylation Disrupts Glioblastoma Cell Proliferation J. Mol. Neurosci. 2019 ORF Clones RC231368
DPYSL2 PlexinA2 and CRMP2 Signaling Complex is Activated by Nogo-A-Liganded NgR1 to Restrict Corticospinal Axon Sprouting after Trauma J. Neurosci. 2019 ORF Clones RC209080
DPYSL2 Peroxiredoxin interaction with the cytoskeletal-regulatory protein CRMP2: Investigation of a putative redox relay Free Radic. Biol. Med. 2018 ORF Clones RC231368
DPYSL2 Tuning microtubule dynamics to enhance cancer therapy by modulating FER-mediated CRMP2 phosphorylation Nat Commun 2018 ORF Clones RC231368
DPYSL5 Pitfalls in the detection of CV2 (CRMP5) antibodies J. Neuroimmunol. Jan 2016 ORF Clones RG202631
DRAM1 mTORC1 Activation Requires DRAM-1 by Facilitating Lysosomal Amino Acid Efflux Mol. Cell 2019 ORF Clones MR220640
DRAM2 DRAM2 acts as an oncogene in non-small cell lung cancer and suppresses the expression of p53 J. Exp. Clin. Cancer Res. 2019 ORF Clones RC213085
DRD1 G-protein coupled receptor 37L1 regulates renal sodium transport and blood pressure Am. J. Physiol. Renal Physiol. 2018 ORF Clones RC210389
Drd1 Dopamine D1-like Receptors Regulate Constitutive, µ-Opioid Receptor-Mediated Repression of Use-Dependent Synaptic Plasticity in Dorsal Horn Neurons: More Harm than Good? J. Neurosci. May 2016 ORF Clones RR202421
DRD2 Renal rescue of dopamine D2 receptor function reverses renal injury and high blood pressure JCI Insight Jun 2016 ORF Clones RC202476
DRD4 Functional characterization of rare variants in human dopamine receptor D4 gene by genotype-phenotype correlations Neuroscience, Jan 2014. ORF Clones RC219722
Drd5 Dopamine D1-like Receptors Regulate Constitutive, µ-Opioid Receptor-Mediated Repression of Use-Dependent Synaptic Plasticity in Dorsal Horn Neurons: More Harm than Good? J. Neurosci. May 2016 ORF Clones RR203152
DTNBP1 Schizophrenia-related dysbindin-1 gene is required for innate immune response and homeostasis in the developing subventricular zone NPJ Schizophr 2018 ORF Clones MR205351
DTX1 Integrative computational analysis of transcriptional and epigenetic alterations implicates DTX1 as a putative tumor suppressor gene in HNSCC Oncotarget 2017 ORF Clones RC208338
DTX4 DYRK2 Negatively Regulates Type I Interferon Induction by Promoting TBK1 Degradation via Ser527 Phosphorylation PLoS Pathog. Sep 2015 ORF Clones RC217321
DUPD1 Inhibition of MAPK by Prolactin Signaling through the Short Form of Its Receptor in the Ovary and Decidua: INVOLVEMENT OF A NOVEL PHOSPHATASE J. Biol. Chem., Mar 2011; 286: 7609 - 7618 ORF Clones RC214361
DUS2 A road map to evaluate the proteome-wide selectivity of covalent kinase inhibitors Nat. Chem. Biol. July 2014 ORF Clones RC200175
DUSP1 Activation of AMPKa2 in adipocytes is essential for nicotine-induced insulin resistance in vivo Nat. Med. Apr 2015 ORF Clones RG205220
DUSP1 Activation of AMPKa2 in adipocytes is essential for nicotine-induced insulin resistance in vivo Nat. Med. Apr 2015 ORF Clones RC205220
DUSP10 mTORC2 modulates feedback regulation of p38 MAPK activity via DUSP10/MKP5 to confer differential responses to PP242 in glioblastoma Genes Cancer Nov 2014 ORF Clones RC206760
DUSP4 Vasoactive intestinal peptide controls the suprachiasmatic circadian clock network via ERK1/2 and DUSP4 signalling Nat Commun 2019 ORF Clones MR222119
DUSP4 Dual-Specificity Phosphatase 4 Overexpression in Cells Prevents Hypoxia/Reoxygenation-Induced Apoptosis via the Upregulation of eNOS Front. Cardiovasc. Med 2017 ORF Clones MR222119
DUSP4 DUSP4 deficiency caused by promoter hypermethylation drives JNK signaling and tumor cell survival in diffuse large B cell lymphoma J. Exp. Med. May 2015 ORF Clones RC200640
DUSP5 Endoplasmic Reticulum Stress Increases DUSP5 Expression via PERK-CHOP Pathway, Leading to Hepatocyte Death Int J Mol Sci 2019 ORF Clones MR221293
DUSP6 Dusp6 is a genetic modifier of growth through enhanced ERK activity Human Molecular Genetics 2018 ORF Clones MR222688
DUSP6 p53-mediated Upregulation of MKP-3 Contributes to the Establishment of Cellular Senescent Phenotype through Dephosphorylation of ERK1/2 J. Biol. Chem. Nov 2014 ORF Clones RG216245
DYNAP Interactions between monomeric CCTδ and p150Glued: a novel function for CCTδ at the cell periphery distinct from the protein folding activity of the molecular chaperone CCT Exp. Cell Res. 2018 ORF Clones RC220689
Dync1li2 Rassf5 and Ndr kinases act in a novel pathway regulating neuronal polarity through Par3 phosphorylation J. Cell. Sci. Jun 2014 ORF Clones MG207876
DYRK1A Dual-specificity tyrosine-phosphorylation regulated kinase 1A Gene Transcription is regulated by Myocyte Enhancer Factor 2D Sci Rep 2017 ORF Clones RC213183
DYRK1B The kinase Mirk is a potential therapeutic target in osteosarcoma Carcinogenesis, Apr 2010; 31: 552 - 558 ORF Clones RC205861
DYRK2 DYRK2 Negatively Regulates Type I Interferon Induction by Promoting TBK1 Degradation via Ser527 Phosphorylation PLoS Pathog. Sep 2015 ORF Clones RC202413
Dyrk2 Stability of the human pregnane X receptor is regulated by E3 ligase UBR5 and serine/threonine kinase DYRK2 Biochem. J., Jan 2014. ORF Clones MR209298
DZIP1 Primary cilia defects causing mitral valve prolapse Sci Transl Med 2019 ORF Clones RC207188
E2F1 MiR-205 enhances cisplatin sensitivity of glioma cells by targeting E2F1 Eur Rev Med Pharmacol Sci 2018 ORF Clones RC208247
E2F1 CDC20B is required for deuterosome-mediated centriole production in multiciliated cells bioRxiv 2017 ORF Clones RC208247
E2F1 Coordination of myeloid differentiation with reduced cell cycle progression by PU.1 induction of microRNAs targeting cell cycle regulators and lipid anabolism Mol. Cell. Biol 2017 ORF Clones MR206856
E2F1 Cip2a promotes cell cycle progression in triple-negative breast cancer cells by regulating the expression and nuclear export of p27Kip1 Oncogene 2016 ORF Clones SC118049
E2F1 Transcription Factors with Conserved Binding Sites Near ATOH1 on the POU4F3 Gene Enhance the Induction of Cochlear Hair Cells Mol. Neurobiol. July 2014 ORF Clones RG208247
E2F4 CDC20B is required for deuterosome-mediated centriole production in multiciliated cells bioRxiv 2017 ORF Clones RC207699
E2F8 Metformin induces cell cycle arrest at the G1 phase through E2F8 suppression in lung cancer cells Oncotarget 2017 ORF Clones RG213597
E7 Comparative Proteomics Reveals Strain-Specific ß-TrCP Degradation via Rotavirus NSP1 Hijacking a Host Cullin-3-Rbx1 Complex PLoS Pathog. 2016 ORF Clones VC101903
EBF2 Comparative Transcriptomic and Epigenomic Analyses Reveal New Regulators of Murine Brown Adipogenesis PLoS Genet 2016 ORF Clones MR224591
EBI3 An Interspecies Analysis Reveals Molecular Construction Principles of Interleukin 27 J. Mol. Biol. 2019 ORF Clones RC208498
EBNA2 Epstein-Barr virus (EBV) activates NKL homeobox gene HLX in DLBCL PLoS ONE 2019 ORF Clones VC101019
EDEM1 ERManI is required for HIV-1 envelope glycoprotein degradation via endoplasmic reticulum-associated protein degradation pathway J. Biol. Chem. Jul 2015 ORF Clones RC205655
EDEM1 MicroRNA-581 Promotes Hepatitis B Virus Surface Antigen Expression by Targeting Dicer and EDEM1 Carcinogenesis Jun 2014 ORF Clones RC205655
EDEM2 ERManI is required for HIV-1 envelope glycoprotein degradation via endoplasmic reticulum-associated protein degradation pathway J. Biol. Chem. Jul 2015 ORF Clones RC200124
EDEM3 EDEM1's mannosidase-like domain binds ERAD client proteins in a redox-sensitive manner and possesses catalytic activity J. Biol. Chem. 2018 ORF Clones RC222885
EDEM3 ERManI is required for HIV-1 envelope glycoprotein degradation via endoplasmic reticulum-associated protein degradation pathway J. Biol. Chem. Jul 2015 ORF Clones RC222885
EDIL3 Elevated autocrine EDIL3 protects hepatocellular carcinoma from anoikis through RGD-mediated integrin activation Mol. Cancer Oct 2014 ORF Clones RC205282
EDNRA Upregulation of the endothelin A (ETA) receptor and its association with neurodegeneration in a rodent model of glaucoma BMC Neurosci 2017 ORF Clones RR214158
EDNRA ETAR and protein kinase A pathway mediate ET-1 sensitization of TRPA1 channel: a molecular mechanism of ET-1-induced mechanical hyperalgesia Mol Pain 2019 ORF Clones RC205385
EDNRB Intracellular Endothelin Type B Receptor-driven Ca2+ Signal Elicits Nitric Oxide Production in Endothelial Cells J. Biol. Chem., Nov 2012; 287: 41023 - 41031. ORF Clones RG204899
EEA1 LSm14A is a processing body-associated sensor of viral nucleic acids that initiates cellular antiviral response in the early phase of viral infection PNAS, Jul 2012; 109: 11770 - 11775. ORF Clones RC215396
EEF1A1 FMRP-dependent Mdm2 dephosphorylation is required for MEF2-induced synapse elimination Hum. Mol. Genet 2016 ORF Clones MR207381
EEF1A1 Combining laser capture microdissection and proteomics reveals an active translation machinery controlling invadosome formation Nat Commun 2018 ORF Clones RC209697
eEF1A1 Expanded Polyalanine Tracts Function as Nuclear Export Signals and Promote Protein Mislocalization via Eukaryotic Translation Elongation Factor 1 Alpha 1 J. Biol. Chem 2017 ORF Clones RC209697
EEF1A1 Novel N-terminal and Lysine Methyltransferases That Target Translation Elongation Factor 1A in Yeast and Human Mol. Cell Proteomics 2016 ORF Clones RC209697
EEF1A2 Translation Elongation Factor eEF1A2 is a Novel Anticancer Target for the Marine Natural Product Plitidepsin Sci Rep 2016 ORF Clones RG210716
EEF1AKMT1 Novel N-terminal and Lysine Methyltransferases That Target Translation Elongation Factor 1A in Yeast and Human Mol. Cell Proteomics 2016 ORF Clones RC205604
EEF2 Combining laser capture microdissection and proteomics reveals an active translation machinery controlling invadosome formation Nat Commun 2018 ORF Clones RC212420
EFEMP1 Epigenetic regulation of EFEMP1 in prostate cancer: biological relevance and clinical potential J. Cell. Mol. Med. Sep 2014 ORF Clones RC214953
EFHA1 EMRE Is a Matrix Ca(2+) Sensor that Governs Gatekeeping of the Mitochondrial Ca(2+) Uniporter Cell Rep Jan 2016 ORF Clones RC205455
EGF Transient Cell-to-Cell Signaling before Mitosis in Cultures of human Bone Marrow-Derived Mesenchymal Stem/Stromal Cells Stem Cells Dev. 2018 ORF Clones RG230667
EGF claMP Tag: A Versatile Inline Metal-Binding Platform Based on the Metal Abstraction Peptide Bioconjug. Chem. May 2014 ORF Clones RC210817
EGFL6 EGFL6 promotes breast cancer by simultaneously enhancing cancer cell metastasis and stimulating tumor angiogenesis Oncogene 2018 ORF Clones RC207729
EGFR LncRNA DUXAP9-206 directly binds with Cbl-b to augment EGFR signaling and promotes non-small cell lung cancer progression J. Cell. Mol. Med. 2018 ORF Clones RC217223
EGFR BRET-based assay to monitor EGFR transactivation by the AT1R reveals Gq/11 protein-independent activation and AT1R-EGFR complexes Biochem. Pharmacol. 2018 ORF Clones RC217223
EGFR BRET-based assay to monitor EGFR transactivation by the AT1R reveals Gq/11 protein-independent activation and AT1R-EGFR complexes Biochem. Pharmacol. 2018 ORF Clones RC209954
EGFR Mabfilin and Fabfilin - New antibody-scaffold fusion formats for multispecific targeting concepts Protein Expr. Purif. 2018 ORF Clones RC217384
EGFR Cellular uptake mediated by epidermal growth factor receptor facilitates the intracellular activity of phosphorothioate-modified antisense oligonucleotides Nucleic Acids Res. 2018 ORF Clones RC217223
EGFR Fatty acid synthase mediates EGFR palmitoylation in EGFR mutated non-small cell lung cancer EMBO Mol Med 2018 ORF Clones RG217384
EGFR MiR-181b modulates EGFR-dependent VCAM-1 expression and monocyte adhesion in glioblastoma Oncogene 2017 ORF Clones RC217223
EGFR A single-nucleotide polymorphism of miR-146a and psoriasis: an association and functional study J. Cell. Mol. Med. Sep 2014 ORF Clones RC217384
EGFR V843I, a Lung Cancer Predisposing EGFR Mutation, Is Responsible for Resistance to EGFR Tyrosine Kinase Inhibitors J Thorac Oncol July 2014 ORF Clones RC217384
EGFR Inhibition of EGFR-induced glucose metabolism sensitizes chondrosarcoma cells to cisplatin Tumour Biol. April 2014 ORF Clones RC214877
EGLN1 Regulation of HIF-1α during Hypoxia by DAP5-Induced Translation of PHD2 Mol. Cell. Biol. 2018 ORF Clones RC215158
EGLN1 Germ-line PHD1 and PHD2 mutations detected in patients with pheochromocytoma/paraganglioma-polycythemia J. Mol. Med. Sep 2014 ORF Clones RC215158
EGLN2 Germ-line PHD1 and PHD2 mutations detected in patients with pheochromocytoma/paraganglioma-polycythemia J. Mol. Med. Sep 2014 ORF Clones RC206152
EGLN3 ROS- and HIF1α-dependent IGFBP3 upregulation blocks IGF1 survival signaling and thereby mediates high-glucose-induced cardiomyocyte apoptosis J. Cell. Physiol. 2019 ORF Clones RC210319
EGR1 Role of Egr1 on Pancreatic Endoderm Differentiation Cell Med 2018 ORF Clones RG209956
EGR1 A Novel Egr-1-Agrin Pathway and Potential Implications for Regulation of Synaptic Physiology and Homeostasis at the Neuromuscular Junction Front Aging Neurosci 2017 ORF Clones RC209956
EGR1 Early growth response-1-mediated down-regulation of drebrin correlates with loss of dendritic spines J. Neurochem. 2017 ORF Clones RC209956
EGR1 Identification of proximal biomarkers of PKC agonism and evaluation of their role in HIV reactivation Antiviral Res. 2016 ORF Clones RG209956
Egr1 Age-Associated Up-Regulation of EGR1 Promotes Granulosa Cell Apoptosis during Follicle Atresia in Mice through the NF-?B Pathway Cell Cycle 2016 ORF Clones MR227136
EGR1 Molecular pathways reflecting poor intrauterine growth are found in Wharton's jelly-derived mesenchymal stem cells Hum. Reprod. Aug 2014 ORF Clones RG209956
EGR1 Clusterin Mediates TGF-ß–Induced Epithelial–Mesenchymal Transition and Metastasis via Twist1 in Prostate Cancer Cells Cancer Res., Oct 2012; 72: 5261 - 5272. ORF Clones RC209956
Egr3 Identification of proximal biomarkers of PKC agonism and evaluation of their role in HIV reactivation Antiviral Res. 2016 ORF Clones RG211140
EGR4 Novel STIM1-dependent control of Ca2+ clearance regulates NFAT activity during T-cell activation FASEB J. 2016 ORF Clones RG221199
EGVEGF Primary Cilium-Regulated EG-VEGF Signaling Facilitates Trophoblast Invasion J. Cell. Physiol. 2016 ORF Clones RC205595
EHHADH Quantitative proteomics reveals the roles of peroxisome-associated proteins in anti-viral innate immune responses Mol. Cell Proteomics Jun 2015 ORF Clones RC207928
EIF2AK2 KSHV inhibits stress granule formation by viral ORF57 blocking PKR activation PLoS Pathog.2017 ORF Clones RC210792
EIF2AK3 eIF2α kinases PERK and GCN2 act on FOXO to potentiate FOXO activity Genes Cells 2018 ORF Clones RC214993
EIF2AK3 The ER Stress Sensor PERK Coordinates ER-Plasma Membrane Contact Site Formation through Interaction with Filamin-A and F-Actin Remodeling Mol. Cell 2017 ORF Clones RC214993
EIF2B5 Cellular eIF2B subunit localization: implications for the integrated stress response and its control by small molecule drugs Mol. Biol. Cell 2019 ORF Clones RG202322
EIF2S1 Cellular eIF2B subunit localization: implications for the integrated stress response and its control by small molecule drugs Mol. Biol. Cell 2019 ORF Clones RG200368
EIF2S2 Regulation of HIF-1α during Hypoxia by DAP5-Induced Translation of PHD2 Mol. Cell. Biol. 2018 ORF Clones RC201563
EIF3B A threonyl-tRNA synthetase-mediated translation initiation machinery Nat Commun 2019 ORF Clones RC200612
EIF3C Eukaryotic translation initiation factor 3 subunit C is associated with acquired resistance to erlotinib in non-small cell lung cancer Oncotarget 2018 ORF Clones RC201705
EIF3C Eukaryotic translation initiation factor 3 subunit C is associated with acquired resistance to erlotinib in non-small cell lung cancer Oncotarget 2018 ORF Clones RG201705
EIF3L Combining laser capture microdissection and proteomics reveals an active translation machinery controlling invadosome formation Nat Commun 2018 ORF Clones RC206690
EIF4A1 Targetome analysis of chaperone-mediated autophagy in cancer cells Autophagy 2019 ORF Clones RC203298
EIF4B MMP13 inhibition rescues cognitive decline in Alzheimer transgenic mice via BACE1 regulation Brain 2019 ORF Clones RC209955
EIF4B ITCH nuclear translocation and H1.2 polyubiquitination negatively regulate the DNA damage response Nucleic Acids Res. 2018 ORF Clones RC209955
EIF4E Cap-dependent Translation Initiation Factor, eIF4E, is the Target for Ouabain-Mediated Inhibition of HIF-1a Biochem. Pharmacol. Dec 2013. ORF Clones RC207333
EIF4E3 A threonyl-tRNA synthetase-mediated translation initiation machinery Nat Commun 2019 ORF Clones RC209694
EIF4EBP1 Translational control of breast cancer plasticity bioRxiv 2019 ORF Clones RC201348
EIF4EBP1 The Translational Repressor 4E-BP1 Contributes to Diabetes-Induced Visual DysfunctionHyperglycemia Attenuates 4E-BP1 Degradation Investigative Ophthalmology & Visual Science Mar 2016 ORF Clones RC201348
Eif4ebp1 Hydrogen Peroxide Regulates Osteopontin Expression through Activation of Transcriptional and Translational Pathways J. Biol. Chem. Nov 2013 ORF Clones RR213165
EIF4H Targetome analysis of chaperone-mediated autophagy in cancer cells Autophagy 2019 ORF Clones RC204028
EIF5A2 Laminin signals initiate the reciprocal loop that informs breast-specific gene expression and homeostasis by activating NO, p53 and microRNAs Elife 2018 ORF Clones RC206249
ELAVL1 Human antigen R protein modulates vascular endothelial growth factor expression in human corneal epithelial cells under hypoxia J. Formos. Med. Assoc. 2019 ORF Clones RC201562
ELAVL1 Dysregulation of tristetraprolin and human antigen R promotes gastric cancer progressions partly by upregulation of the high-mobility group box 1 Sci Rep 2018 ORF Clones RC201562
ELAVL1 Studying the mechanism of PLAGL2 overexpression and its carcinogenic characteristics based on 3'-untranslated region in colorectal cancer Int. J. Oncol. 2018 ORF Clones MR204748
ELAVL1 Discovering the 3' UTR-mediated regulation of alpha-synuclein Nucleic Acids Res. 2017 ORF Clones RG201562
ELAVL2 Genome-scale CRISPR activation screening identifies a role of ELAVL2-CDKN1A axis in paclitaxel resistance in esophageal squamous cell carcinoma Am J Cancer Res 2019 ORF Clones RC229918
ELAVL3 The neural ELAVL protein HuB enhances endogenous proto-oncogene activation Biochem. Biophys. Res. Commun. 2019 ORF Clones RC204323
ELAVL4 The neural ELAVL protein HuB enhances endogenous proto-oncogene activation Biochem. Biophys. Res. Commun. 2019 ORF Clones RC218612
ELK1 Pro-inflammatory cytokines IL-6 and CCL2 suppress expression of circadian gene Period2 in mammary epithelial cells Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 2018 ORF Clones RC208921
ELK1 The Amino-terminal Domain of the Androgen Receptor Co-opts ERK Docking Sites in ELK1 to Induce Sustained Gene Activation that Supports Prostate Cancer Cell Growth J. Biol. Chem. 2016 ORF Clones RC208921
ELK1 Erlotinib derivative inhibits hepatocellular carcinoma by targeting CIP2A to reactivate protein phosphatase 2A Cell Death Dis Aug 2014 ORF Clones RG208921
ELL2 The transcription elongation factor ELL2 is specifically upregulated in HTLV-1-infected T-cells and is dependent on the viral oncoprotein tax Virology July 2014 ORF Clones RC206204
ELMOD2 ELMOD2 regulates mitochondrial fusion in a mitofusin-dependent manner, downstream of ARL2 Mol. Biol. Cell 2019 ORF Clones MR204034
ELOVL2 E2F1 Orchestrates Transcriptomics and Oxidative Metabolism in Wharton's Jelly-Derived Mesenchymal Stem Cells from Growth-Restricted Infants PLoS ONE 2016 ORF Clones RC209232
ELP3 Elongator subunit 3 (ELP3) modifies ALS through tRNA modification Hum. Mol. Genet. 2018 ORF Clones RC201491
Emc3 EMC3 coordinates surfactant protein and lipid homeostasis required for respiration J. Clin. Invest.2017 ORF Clones MR203415
EMD Isolated nuclei adapt to force and reveal a mechanotransduction pathway in the nucleus Nat. Cell Biol. Mar 2014 ORF Clones MR222146
EMILIN3 Genetic compensation induced by deleterious mutations but not gene knockdowns Nature Jul 2015 ORF Clones MR210504
EMP1 p53, miR-34a and EMP1-Newly Identified Targets of TFF3 Signaling in Y79 Retinoblastoma Cells Int J Mol Sci 2019 ORF Clones RC208410
EMX1 Pancreatic Neuroendocrine Tumors and EMT Behavior are Driven by the CSC Marker DCLK1 Mol. Cancer Res 2017 ORF Clones RC208006
EMX2 Parkinson-associated risk variant in distal enhancer of a-synuclein modulates target gene expression Nature Apr 2016 ORF Clones RC222758
EN2 Membrane insertion and secretion of the Engrailed-2 (EN2) transcription factor by prostate cancer cells may induce antiviral activity in the stroma Sci Rep 2019 ORF Clones RC211220
ENPP1 Neutrophils as sources of dinucleotide polyphosphates and metabolism by epithelial ENPP1 to influence barrier function via adenosine signaling Mol. Biol. Cell 2018 ORF Clones RC209222
ENPP1 Synthesis and biological evaluation of novel quinazoline-4-piperidinesulfamide derivatives as inhibitors of NPP1 Eur J Med Chem 2018 ORF Clones RG209222
ENPP1 Loss of microRNA-27b contributes to breast cancer stem cell generation by activating ENPP1 Nat Commun Jun 2015 ORF Clones RC209222
ENSA Fcp1 phosphatase controls Greatwall kinase to promote PP2A-B55 activation and mitotic progression Elife Dec 2015 ORF Clones RC220441
EOMES Reciprocal regulation of BMF and BIRC5 (Survivin) linked to Eomes overexpression in colorectal cancer Cancer Lett. 2016 ORF Clones RG221014
EOMES The evolution of basal progenitors in the developing non-mammalian brain Development Jan 2016 ORF Clones MR210179
EP300 Chronic sun exposure is associated with distinct histone acetylation changes in human skin Br. J. Dermatol.2017 ORF Clones RG223265
EP300 Genomic Profiling of Adult and Pediatric B-cell Acute Lymphoblastic Leukemia EBioMedicine 2016 ORF Clones RC223265
EP300 The membrane protein melanoma cell adhesion molecule (MCAM) is a novel tumor marker that stimulates tumorigenesis in hepatocellular carcinoma Oncogene Mar 2015 ORF Clones RC223265
EP4 Targeting EP4 downstream c-Jun through ERK1/2-mediated reduction of DNMT1 reveals novel mechanism of solamargine-inhibited growth of lung cancer cells J. Cell. Mol. Med. 2016 ORF Clones MG226255
EPAS1 A novel hypoxia response element regulates oxygen-related repression of tissue factor pathway inhibitor in the breast cancer cell line MCF-7 Thromb. Res. 2017 ORF Clones RC208604
EPAS1 Reciprocal regulation by hypoxia-inducible factor-2a and the NAMPT-NAD(+)-SIRT axis in articular chondrocytes is involved in osteoarthritis Osteoarthr. Cartil. Jul 2015 ORF Clones MR211029
EPB41L4B The splice variant Ehm2/1 in breast cancer MCF-7 cells interacted with ß-catenin and increased its localization to plasma membrane RSC Advances 2016 ORF Clones RC223085
EPCAM The IgM CH2 domain as covalently linked homodimerization module for the generation of fusion proteins with dual specificity Protein Eng. Des. Sel., Oct 2012; 25: 603 - 612. ORF Clones RG201989
EPHA1 Decreased Eph receptor‑A1 expression is related to grade in ovarian serous carcinoma Mol Med Rep 2018 ORF Clones RG213689
Epha1 The E3 ubiquitin ligase RNF114 and TAB1 degradation are required for maternal-to-zygotic transition EMBO Rep 2017 ORF Clones MR211365
EPHA2 EPHA2 mutations with oncogenic characteristics in squamous cell lung cancer and malignant pleural mesothelioma Oncogenesis 2019 ORF Clones RG205725
EPHA2 Manipulation of cell-type selective antibody internalization by a guide-effector bispecific design Mol. Cancer Ther. 2019 ORF Clones RC205725
EPHA2 EphA2 receptor is a key player in the metastatic onset of Ewing sarcoma Int. J. Cancer 2018 ORF Clones RC205725
EPHA2 Cell-type specific potent Wnt signaling blockade by bispecific antibody Sci Rep 2018 ORF Clones RC205725
EPHA2 High Affinity Binders to EphA2 Isolated from Abdurin Scaffold Libraries; Characterization, Binding and Tumor Targeting PLoS ONE Aug 2015 ORF Clones RC205725
EPHA4 Identification and Characterisation of Nanobodies targeting the EphA4 receptor J. Biol. Chem. 2017 ORF Clones RC211230
EPHA5 Receptor Tyrosine Kinase EphA5 is a Functional Molecular Target in Human Lung Cancer J. Biol. Chem. Jan 2015 ORF Clones RG213206
EPHA7 Generation and characterization of a single-chain anti-EphA2 antibody Growth Factors Nov 2014 ORF Clones RC226293
EPHB1 EphrinB2 drives perivascular invasion and proliferation of glioblastoma stem-like cells Elife 2016 ORF Clones RC214301
EPHB3 Upregulation of EphB3 in gastric cancer with acquired resistance to a FGFR inhibitor Int. J. Biochem. Cell Biol. 2018 ORF Clones RG208364
EPHB3 Mule Regulates the Intestinal Stem Cell Niche via the Wnt Pathway and Targets EphB3 for Proteasomal and Lysosomal Degradation Cell Stem Cell 2016 ORF Clones RC208364
EPHB4 EPHB4 kinase-inactivating mutations cause autosomal dominant lymphatic-related hydrops fetalis J. Clin. Invest. 2016 ORF Clones RC208559
EPHB4 Ligand stimulation induces clathrin- and Rab5-dependent downregulation of the kinase-dead EphB6 receptor preceded by the disruption of EphB6-Hsp90 interaction Cell. Signal. Aug 2014 ORF Clones RG208559
EPHX2 Soluble epoxide hydrolase modulates immune responses in activated astrocytes involving regulation of STAT3 activity J Neuroinflammation 2019 ORF Clones MR208783
EPN1 Spatiotemporal control of endocytosis by phosphatidylinositol-3,4-bisphosphate Nature 499, 233-237 doi:10.1038/nature12360 ORF Clones RC207099
EPO Digital PCR detection of plasmid DNA administered to the skeletal muscle of a microminipig: a model case study for gene doping detection BMC Res Notes 2018 ORF Clones RC210775
EPO Erythropoietin Slows Photoreceptor Cell Death in a Mouse Model of Autosomal Dominant Retinitis Pigmentosa PLoS ONE Jun 2016 ORF Clones RC210775
EPO Probing protease sensitivity of recombinant human erythropoietin reveals a3-a4 inter-helical loop as a stability determinant Proteins Jul 2015 ORF Clones RC210775
EPRS Structural control of caspase-generated glutamyl-tRNA synthetase by appended noncatalytic WHEP domains J. Biol. Chem. 2018 ORF Clones MR218237
ER a Synthesis and structure-activity relationships of 1-benzylindane derivatives as selective agonists for estrogen receptor beta Bioorg. Med. Chem. 2016 ORF Clones RC213277
ERAS Discovery of novel oestrogen receptor α agonists and antagonists by screening a revisited privileged structure moiety for nuclear receptors Sci Rep 2019 ORF Clones RC210965
ERAS The function of embryonic stem cell-expressed Ras (E-Ras), a unique Ras family member, correlates with its additional motifs and its structural properties J. Biol. Chem. May 2015 ORF Clones RG210965
ERAS BRAF inhibitor resistance mediated by the AKT pathway in an oncogenic BRAF mouse melanoma model Proc. Natl. Acad. Sci. U.S.A. Jan 2015 ORF Clones RC210965
ERBB2 High cell-surface density of HER2 deforms cell membranes Nat Commun 2016 ORF Clones RG212583
ERBB2 Star-related lipid transfer protein 10 (STARD10): a novel key player in alcohol-induced breast cancer progression J. Exp. Clin. Cancer Res. 2019 ORF Clones RG212583
ERBB2 BRET-based assay to monitor EGFR transactivation by the AT1R reveals Gq/11 protein-independent activation and AT1R-EGFR complexes Biochem. Pharmacol. 2018 ORF Clones RC212583
ERBB2 Mabfilin and Fabfilin - New antibody-scaffold fusion formats for multispecific targeting concepts Protein Expr. Purif. 2018 ORF Clones RG212583
ERBB2 Epitope Mapping of Human HER2 Specific Mouse Monoclonal Antibodies Using Recombinant Extracellular Subdomains Asian Pac. J. Cancer Prev. 2017 ORF Clones RC600005
ERBB2 miR-125b acts as a tumor suppressor in chondrosarcoma cells by the sensitization to doxorubicin through direct targeting the ErbB2-regulated glucose metabolism Drug Des Devel Ther Mar 2016 ORF Clones RC212583
ERBB2 Overexpression of ErbB2 renders breast cancer cells susceptible to 3-BrPA through the increased dissociation of hexokinase II from mitochondrial outer membrane Oncology letters Feb 2016 ORF Clones RC212583
ErbB2 Screening and discovery of nitro-benzoxadiazole compounds activating epidermal growth factor receptor (EGFR) in cancer cells Sci Rep, Feb 2014. ORF Clones RC212583
ERBB3 A ROR1-HER3-lncRNA signalling axis modulates the Hippo-YAP pathway to regulate bone metastasis Nat. Cell Biol 2017 ORF Clones RC209954
ERBB3 Deficient HER3 expression in poorly-differentiated colorectal cancer cells enhances gefitinib sensitivity Int. J. Oncol. July 2014 ORF Clones RC209954
ERBB4 ErbB4 cleavage by gonadotropin-releasing hormone receptor stimulation in cultured gonadotroph cells Eur. J. Pharmacol 2017 ORF Clones MR225933
ERBB4 Effect of ErbB4 on Triple Negative Breast Cancer Cell Growth and Migration Thesis . 2014 ORF Clones RG220500
ERBIN ERBIN deficiency links STAT3 and TGF-ß pathway defects with atopy in humans J. Exp. Med 2017 ORF Clones RG235298
eRF3a Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes Cell 2016 ORF Clones RC229318
ERG Multiplexed Electrochemical Cancer Diagnostics With Automated Microfluidics Electroanalysis 2018 ORF Clones RC227285
ERGIC3 Endoplasmic reticulum-Golgi intermediate compartment protein 3 knockdown suppresses lung cancer through endoplasmic reticulum stress-induced autophagy Oncotarget 2016 ORF Clones RG204084
ERß Synthesis and structure-activity relationships of 1-benzylindane derivatives as selective agonists for estrogen receptor beta Bioorg. Med. Chem. 2016 ORF Clones RC218519
ESD An activity-dependent proximity ligation platform for spatially resolved quantification of active enzymes in single cells Nat Commun 2017 ORF Clones RC200533
ESPN Overexpression of microRNA-612 Restrains the Growth, Invasion, and Tumorigenesis of Melanoma Cells by Targeting Espin Mol. Cells 2018 ORF Clones RC212577
ESR1 Receptor-binding affinities of bisphenol A and its next-generation analogs for human nuclear receptors Toxicol. Appl. Pharmacol. 2019 ORF Clones RC213277
ESR1 Receptor-binding affinities of bisphenol A and its next-generation analogs for human nuclear receptors Toxicol. Appl. Pharmacol. 2019 ORF Clones RC226003
ESR1 ERα upregulates the expression of long non-coding RNA LINC00472 which suppresses the phosphorylation of NF-κB in breast cancer Breast Cancer Res. Treat. 2019 ORF Clones RC213277
ESR1 Polyfluorinated iodine alkanes regulated distinct breast cancer cell progression through binding with estrogen receptor alpha or beta isoforms Environ. Pollut. 2018 ORF Clones RC213277
ESR1 Estrogen receptor regulates hormone-induced growth arrest in a luminal A like breast cancer model bioRxiv 2018 ORF Clones RC213277
ESR1 ER alpha binding by transcription factors NFIB and YBX1 enables FGFR2 signalling to modulate estrogen responsiveness in breast cancer Cancer Res.2017 ORF Clones RC213277
ESR1 RIZ1 is regulated by estrogen and suppresses tumor progression in endometrial cancer Biochem. Biophys. Res. Commun. 2017 ORF Clones RC213277
ESR1 Targeting Estrogen Receptor Signaling with Fulvestrant Enhances Immune and Chemotherapy-Mediated Cytotoxicity of Human Lung Cancer Clin. Cancer Res 2016 ORF Clones RC213277
ESR1 EFEMP1 is repressed by estrogen and inhibits the epithelial-mesenchymal transition via Wnt/ß-catenin signaling in endometrial carcinoma Oncotarget 2016 ORF Clones RG213277
ESR1 Let-7c blocks estrogen-activated Wnt signaling in induction of self-renewal of breast cancer stem cells Cancer Gene Ther. Mar 2016 ORF Clones RC213277
ESR1 Estrogen receptor alpha inhibits RLR-mediated immune response via ubiquitinating TRAF3 Cell. Signal. Jul 2015 ORF Clones RC213277
ESR1 Estrogen receptor a enhances the transcriptional activity of ETS-1 and promotes the proliferation, migration and invasion of neuroblastoma cell in a ligand dependent manner BMC Cancer Jun 2015 ORF Clones RC213277
ESR2 17β-estradiol upregulates IL6 expression through the ERβ pathway to promote lung adenocarcinoma progression J. Exp. Clin. Cancer Res. 2018 ORF Clones RC218519
ESR2 Polyfluorinated iodine alkanes regulated distinct breast cancer cell progression through binding with estrogen receptor alpha or beta isoforms Environ. Pollut. 2018 ORF Clones RC218519
ESR2 The nuclear receptor ERβ engages AGO2 in regulation of gene transcription, RNA splicing and RISC loading Genome Biol. 2017 ORF Clones RC218519
ESR2 The Phytoestrogen Genistein Affects Breast Cancer Cells Treatment Depending on the ERa/ERß Ratio J. Cell. Biochem. Jun 2015 ORF Clones RC218519
ETF1 Structural basis for stop codon recognition in eukaryotes Nature Aug 2015 ORF Clones RC220387
ETFDH Neurite growth could be impaired by ETFDH mutation but restored by mitochondrial cofactors Muscle Nerve 2016 ORF Clones RC204149
ETS1 Batf Pioneers the Reorganization of Chromatin in Developing Effector T Cells via Ets1-Dependent Recruitment of Ctcf Cell Rep 2019 ORF Clones MR207015
ETS1 ETS1 regulates Twist1 transcription in a Kras G12D /Lkb1-/- metastatic lung tumor model of non-small cell lung cancer Clin. Exp. Metastasis 2018 ORF Clones RC227466
ETS1 Estrogen receptor a enhances the transcriptional activity of ETS-1 and promotes the proliferation, migration and invasion of neuroblastoma cell in a ligand dependent manner BMC Cancer Jun 2015 ORF Clones RC227466
ETS1 SLFN11 is a transcriptional target of EWS-FLI1 and a determinant of drug response in Ewing's sarcoma Clin. Cancer Res. Mar 2015 ORF Clones RC227466
ETS2 Transcription Factors with Conserved Binding Sites Near ATOH1 on the POU4F3 Gene Enhance the Induction of Cochlear Hair Cells Mol. Neurobiol. July 2014 ORF Clones RC207377
ETV1 Genome-wide analysis of ETV1 targets: Insights into the role of ETV1 in tumor progression J. Cell. Biochem. 2019 ORF Clones RC210533
ETV3L Comparison of